Spectrum of findings and usefulness of integrated PET/CT in patients with known or suspected neuroendocrine tumors of the lung

Abstract Positron emission tomography (PET) with fluorine-18 fluorodeoxyglucose (FDG) has been known to increase diagnostic accuracy in differentiating benign and malignant lung lesions and to improve identification of lymph node and extrathoracic metastasis in pulmonary neoplasms. In this review, the authors describe the spectrum of integrated PET/CT findings on neuroendocrine (NE) tumors of the lung. We also demonstrate the usefulness of this imaging modality in patients with known or suspected NE tumors of the lung.

[1]  J. Choi,et al.  Integrated PET/CT of pulmonary neuroendocrine tumors: diagnostic and prognostic implications. , 2007, AJR. American journal of roentgenology.

[2]  F. Mottaghy,et al.  Use of integrated FDG PET/CT imaging in pulmonary carcinoid tumours , 2006, Journal of internal medicine.

[3]  M. Chung,et al.  Neuroendocrine tumors of the lung: clinical, pathologic, and imaging findings. , 2006, Radiographics : a review publication of the Radiological Society of North America, Inc.

[4]  A. Pecking,et al.  Typical and atypical bronchopulmonary carcinoid tumors on FDG PET/CT imaging. , 2004, Clinical nuclear medicine.

[5]  D. Ball,et al.  Impact of Positron Emission Tomography on the Management of Patients With Small-Cell Lung Cancer: Preliminary Experience , 2004, American journal of clinical oncology.

[6]  Y. Shimosato [Histological Typing of Lung and Pleural Tumors (3rd edition, 1999): Malignant epithelial tumors]. , 2002, Nihon rinsho. Japanese journal of clinical medicine.

[7]  S. Larson,et al.  Prognostic value of [18F]FDG-PET imaging in small cell lung cancer , 2002, European Journal of Nuclear Medicine and Molecular Imaging.

[8]  C. Compton,et al.  AJCC Cancer Staging Manual , 2002, Springer New York.

[9]  J R Galvin,et al.  Thoracic carcinoids: radiologic-pathologic correlation. , 1999, Radiographics : a review publication of the Radiological Society of North America, Inc.

[10]  Y. Shimosato,et al.  Histological Typing of Lung and Pleural Tumours , 1999, World Health Organization.

[11]  W. Travis,et al.  Survival analysis of 200 pulmonary neuroendocrine tumors with clarification of criteria for atypical carcinoid and its separation from typical carcinoid. , 1998, The American journal of surgical pathology.

[12]  P C Goodman,et al.  Evaluation of primary pulmonary carcinoid tumors using FDG PET. , 1998, AJR. American journal of roentgenology.

[13]  C. Mountain,et al.  Regional lymph node classification for lung cancer staging. , 1997, Chest.

[14]  W. Travis,et al.  Neuroendocrine Tumors of the Lung With Proposed Criteria for Large‐Cell Neuroendocrine Carcinoma: An Ultrastructural, Immunohistochemical, and Flow Cytometric Study of 35 Cases , 1991, The American journal of surgical pathology.

[15]  M. Zelen Keynote address on biostatistics and data retrieval. , 1973, Cancer chemotherapy reports. Part 3.