Noninvasive Assessment of Human Gastric Motor Function

A noninvasive technique to monitor gastric electrical activity (GEA) and mechanical activity as an aid in assessing gastric motor function is presented. The GEA is measured with ordinary ECG electrodes located on the torso in the region above the stomach. The mechanical activity is recorded through an electrical impedance monitoring device. A study of a mathematical model of the electrically active antral part of the stomach in the body revealed that the waveform of the extracorporeally measured signals can be related to the direction of propagation of the GEA. This feature was confirmed experimentally.

[1]  R. M. Arthur,et al.  Effect of inhomogeneities on the apparent location and magnitude of a cardiac current dipole source. , 1970, IEEE transactions on bio-medical engineering.

[2]  G. S. Herman-Giddens,et al.  Selection of the number and positions of measuring locations for electrocardiography. , 1971, IEEE transactions on bio-medical engineering.

[3]  D. Geselowitz,et al.  Simulation Studies of the Electrocardiogram: I. The Normal Heart , 1978, Circulation research.

[4]  T. Y. El-Sharkawy,et al.  Intracellular electrical activity of canine and human gastric smooth muscle. , 1978, The Journal of physiology.

[5]  R. Smallwood,et al.  Electrical arrhythmias in the human stomach. , 1981, Gut.

[6]  D B Geselowitz,et al.  Simulation Studies of the Electrocardiogram: II. Ischemia and Infarction , 1978, Circulation research.

[7]  F. Roberge,et al.  Representation of Cardiac Electrical Activity by a Moving Dipole for Normal and Ectopic Beats in the Intact Dog , 1980, Circulation research.

[8]  Dietrich Lehmann,et al.  Evaluation of Methods for Three-Dimensional Localization of Electrical Sources in the Human Brain , 1978, IEEE Transactions on Biomedical Engineering.

[9]  M. Lynn,et al.  The application of electromagnetic theory to electrocardiology. II. Numerical solution of the integral equations. , 1967, Biophysical journal.

[10]  W. Chey,et al.  Electrogastrographic study of patients with unexplained nausea, bloating, and vomiting. , 1980, Gastroenterology.

[11]  M. Lynn,et al.  The application of electromagnetic theory to electrocardiology. I. Derivation of the integral equations. , 1967, Biophysical journal.

[12]  John G. Webster,et al.  An Improved Method for Recording and Analyzing the Electrical Activity of the Human Stomach , 1985, IEEE Transactions on Biomedical Engineering.

[13]  J. Dennis,et al.  Derivative free analogues of the Levenberg-Marquardt and Gauss algorithms for nonlinear least squares approximation , 1971 .

[14]  S. Rush,et al.  Resistivity of Body Tissues at Low Frequencies , 1963, Circulation research.

[15]  T. Abell,et al.  Glucagon-evoked gastric dysrhythmias in humans shown by an improved electrogastrographic technique. , 1985, Gastroenterology.

[16]  W. Chey,et al.  Study of electromechanical activity of the stomach in humans and in dogs with particular attention to tachygastria. , 1984, Gastroenterology.

[17]  Potentials Produced by Arbitrary Current Sources in an Infinite-and Finite-Length Circular Conducting Cylinder , 1985, IEEE Transactions on Biomedical Engineering.

[18]  D B Geselowitz,et al.  Quadrupole components of the human surface electrocardiogram. , 1972, American heart journal.

[19]  R. Okada.  Potentials Produced by an Eccentric Current Dipole in a Finite-Length Circular Conducting Cylinder , 1956 .