Computer Aided Lung Nodule Detection on CT Data

A new computer-aided detection (CAD) scheme for detecting lung nodules is proposed in this paper. Firstly, the lung region is segmented from the CT data using adaptive threshold algorithm etc; Secondly, building active contour model to segment and remove lung vessel accurately in the lung region; Next, suspicious nodules are detected and omitted renal vessel is filtered using a selective shape filter; Finally, nodule features are extracted and rule-based classifier is used to distinguish true or false positive nodules. Experiment results indicate that this scheme can help radiologist improve the diagnosis efficiency.

[1]  K. Doi,et al.  Current status and future potential of computer-aided diagnosis in medical imaging. , 2005, The British journal of radiology.

[2]  Qiang Li,et al.  Analysis and minimization of overtraining effect in rule-based classifiers for computer-aided diagnosis. , 2006, Medical physics.

[3]  Berkman Sahiner,et al.  Computer-aided characterization of mammographic masses: accuracy of mass segmentation and its effects on characterization , 2001, IEEE Transactions on Medical Imaging.

[4]  Qiang Li,et al.  Recent progress in computer-aided diagnosis of lung nodules on thin-section CT , 2007, Comput. Medical Imaging Graph..

[5]  Jamshid Dehmeshki,et al.  Shape-Based Computer-Aided Detection of Lung Nodules in Thoracic CT Images , 2009, IEEE Transactions on Biomedical Engineering.

[6]  Lubomir M. Hadjiiski,et al.  Computer-aided detection of lung nodules: false positive reduction using a 3D gradient field method and 3D ellipsoid fitting. , 2005, Medical physics.

[7]  J. Sethian,et al.  Fronts propagating with curvature-dependent speed: algorithms based on Hamilton-Jacobi formulations , 1988 .

[8]  Hiroshi Fujita,et al.  Automated detection of pulmonary nodules in helical CT images based on an improved template-matching technique , 2001, IEEE Transactions on Medical Imaging.

[9]  G. G. Stokes "J." , 1890, The New Yale Book of Quotations.

[10]  M. McNitt-Gray,et al.  Patient-specific models for lung nodule detection and surveillance in CT images , 2001, IEEE Transactions on Medical Imaging.

[11]  T. Freer,et al.  Screening mammography with computer-aided detection: prospective study of 12,860 patients in a community breast center. , 2001, Radiology.

[12]  S. Armato,et al.  Massive training artificial neural network (MTANN) for reduction of false positives in computerized detection of lung nodules in low-dose computed tomography. , 2003, Medical physics.

[13]  K. Awai,et al.  Pulmonary nodules at chest CT: effect of computer-aided diagnosis on radiologists' detection performance. , 2004, Radiology.

[14]  S. Armato,et al.  Automated detection of lung nodules in CT scans: preliminary results. , 2001, Medical physics.