H4IIE rat hepatoma cell bioassay-derived 2,3,7,8-tetrachlorodibenzo-p-dioxin equivalents in colonial fish-eating waterbird eggs from the Great Lakes

[1]  L. Birnbaum,et al.  Toxic interaction of specific polychlorinated biphenyls and 2,3,7,8-tetrachlorodibenzo-p-dioxin: increased incidence of cleft palate in mice. , 1985, Toxicology and applied pharmacology.

[2]  D. Peakall,et al.  Dove reproduction and retinoid (vitamin A) dynamics in adult females and their eggs following exposure to 3,3′,4,4′-tetrachlorobiphenyl , 1989 .

[3]  B. Bush,et al.  PCB levels in egg yolks associated with embryonic mortality and deformity of hatched chicks , 1973, Archives of environmental contamination and toxicology.

[4]  J. Bradlaw,et al.  Induction of aryl hydrocarbon hydroxylase activity in cell cultures by aroclors, residues from yusho oil samples, and polychlorinated biphenyl residues from fish samples. , 1982, Journal - Association of Official Analytical Chemists.

[5]  S. Safe,et al.  Immunosuppressive activities of polychlorinated dibenzofuran congeners: quantitative structure-activity relationships and interactive effects. , 1988, Toxicology and applied pharmacology.

[6]  G. Elder Porphyria Caused by Hexachlorobenzene and Other Polyhalogenated Aromatic Hydrocarbons , 1978 .

[7]  B. J. Puma,et al.  Screening of fresh water fish extracts for enzyme-inducing substances by an aryl hydrocarbon hydroxylase induction bioassay technique. , 1983, Journal - Association of Official Analytical Chemists.

[8]  Lawrence M. Smith,et al.  Microcontaminants and reproductive impairment of the Forster's tern on Green Bay, Lake Michigan-1983 , 1989, Archives of environmental contamination and toxicology.

[9]  R. Norstrom,et al.  Yolk retinoids (vitamin a) in eggs of the herring gull and correlations with polychlorinated dibenzo‐p‐dioxins and dibenzofurans , 1990 .

[10]  T. Kubiak,et al.  Reproductive Outcomes in Colonial Fish-Eating Birds: A Biomarker for Developmental Toxicants in Great Lakes Food Chains: II. Spatial Variation in the Occurrence and Prevalence of Bill Defects in Young Double-Crested Cormorants in the Great Lakes, 1979–1987 , 1991 .

[11]  A. D. Campbell,et al.  Chemical and Toxicological Evaluations of Isolated and Synthetic Chloro Derivatives of Dibenzo-p-dioxin , 1968, Nature.

[12]  D. Nebert,et al.  Induction of Aryl Hydrocarbon Hydroxylase Activity in Various Cell Cultures by 2,3,7,8-Tetrachlorodibenzo-p-dioxin , 1975 .

[13]  L. Hansen,et al.  Effects of purified polychlorinated biphenyl analogs on chicken reproduction. , 1975, Poultry science.

[14]  B. G. Oliver,et al.  Assessment of relative toxicity of chlorinated dibenzo-dioxins, dibenzofurans, and biphenyls in Lake Ontario salmonids to mammalian systems using toxic equivalent factors (TEP) , 1989 .

[15]  D. J. Finney Statistical Method in Biological Assay , 1966 .

[16]  B. Brunström Toxicity of coplanar polychlorinated biphenyls in avian embryos , 1989 .

[17]  S. Safe,et al.  Polychlorinated biphenyls: correlation between in vivo and in vitro quantitative structure-activity relationships (QSARs). , 1985, Journal of toxicology and environmental health.

[18]  J. Whitlock The regulation of gene expression by 2,3,7,8-tetrachlorodibenzo-p-dioxin. , 1987, Pharmacological reviews.

[19]  T. Kubiak,et al.  Embryotoxicity, teratogenicity, and aryl hydrocarbon hydroxylase activity in Forster's terns on Green Bay, Lake Michigan. , 1987, Environmental research.

[20]  J. Giesy,et al.  Planar chlorinated hydrocarbons (PCHs) in colonial fish-eating waterbird eggs from the Great Lakes , 1989 .

[21]  S. Safe,et al.  Aroclor 1254 as a 2,3,7,8-tetrachlorodibenzo-p-dioxin antagonist: effects on enzyme induction and immunotoxicity. , 1987, Toxicology.

[22]  M. Gilbertson Etiology of chick edema disease in Herring Gulls in the lower Great Lakes , 1983 .

[23]  R. A. Neal,et al.  The Ah Receptor: A Biochemical and Biologic Perspective , 1985 .

[24]  E. Glover,et al.  Studies on the mechanism of toxicity of the chlorinated dibenzo-p-dioxins. , 1973, Environmental health perspectives.

[25]  O. H. Lowry,et al.  Protein measurement with the Folin phenol reagent. , 1951, The Journal of biological chemistry.

[26]  D. Whittle,et al.  The status of selected organics in the Laurentian Great Lakes: an overview of DDT, PCBs, dioxins, furans, and aromatic hydrocarbons , 1988 .

[27]  G. Fries,et al.  Embryotoxic and teratogenic effects in unhatched fertile eggs from hens fed polychlorinated biphenyls (PCBs) , 1974, Bulletin of environmental contamination and toxicology.

[28]  S. Safe,et al.  In vitro AHH induction by polychlorinated biphenyl and dibenzofuran mixtures: Additive effects , 1985 .

[29]  J. Bradlaw,et al.  Induction of enzyme activity in cell culture: a rapid screen for detection of planar polychlorinated organic compounds. , 1979, Journal - Association of Official Analytical Chemists.

[30]  Stephenie P. Joyner SAS/STAT guide for personal computers, version 6 edition , 1985 .

[31]  L. Birnbaum,et al.  Cellular alterations and enhanced induction of cleft palate after coadministration of retinoic acid and TCDD. , 1989, Toxicology and applied pharmacology.

[32]  A Poland,et al.  2,3,7,8-tetrachlorodibenzo-p-dioxin and related halogenated aromatic hydrocarbons: examination of the mechanism of toxicity. , 1982, Annual review of pharmacology and toxicology.

[33]  Brian B. Looney,et al.  Airborne organic contaminants in the Great Lakes ecosystem , 1981 .

[34]  J. Giesy,et al.  Characterization of the H4IIE rat hepatoma cell bioassay as a tool for assessing toxic potency of planar halogenated hydrocarbons in environmental samples , 1991 .

[35]  S. Safe Determination of 2,3,7,8-TCDD toxic equivalent factors (TEFs): support for the use of the in vitro AHH induction assay , 1987 .

[36]  J. Haseman,et al.  Teratogenic potency of TCDD, TCDF and TCDD-TCDF combinations in C57BL/6N mice. , 1985, Toxicology letters.

[37]  M. Gilbertson,et al.  POLLUTANT-ASSOCIATED EMBRYONIC MORTALITY OF GREAT LAKES HERRING GULLS. , 1977 .

[38]  B. Brunström Activities in chick embryos of 7-ethoxycoumarin O-deethylase and aryl hydrocarbon (benzo[a]pyrene) hydroxylase and their induction by 3,3',4,4'-tetrachlorobiphenyl in early embryos. , 1986, Xenobiotica; the fate of foreign compounds in biological systems.

[39]  M. Romkes,et al.  Polychlorinated dibenzofurans (PCDFs): correlation between in vivo and in vitro structure-activity relationships. , 1985, Toxicology.

[40]  S. Safe,et al.  Polychlorinated biphenyls (PCBs), dibenzo-p-dioxins (PCDDs), dibenzofurans (PCDFs), and related compounds: environmental and mechanistic considerations which support the development of toxic equivalency factors (TEFs). , 1990, Critical reviews in toxicology.

[41]  S. Kennedy,et al.  Porphyria in herring gulls: A biochemical response to chemical contamination of great lakes food chains , 1988 .

[42]  Stephen Safe,et al.  Comparative aryl hydrocarbon hydroxylase induction activities of commercial PCBs in Wistar rats and rat hepatoma H-4-II E cells in culture , 1984 .

[43]  S. Safe,et al.  Comparative toxicology and mechanism of action of polychlorinated dibenzo-p-dioxins and dibenzofurans. , 1986, Annual review of pharmacology and toxicology.

[44]  S. Safe,et al.  PCB isomers and congeners: induction of aryl hydrocarbon hydroxylase and ethoxyresorufin O-deethylase enzyme activities in rat hepatoma cells. , 1982, Toxicology letters.

[45]  S. Tanabe,et al.  Highly toxic coplanar PCBs: occurrence, source, persistency and toxic implications to wildlife and humans. , 1987, Environmental pollution.

[46]  M. Romkes,et al.  Polychlorinated dibenzofurans (PCDFs): effects of structure on binding to the 2,3,7,8-TCDD cytosolic receptor protein, AHH induction and toxicity. , 1984, Toxicology.

[47]  J. Fouts,et al.  A rapid method for assaying the metabolism of 7-ethoxyresorufin by microsomal subcellular fractions. , 1980, Analytical biochemistry.