Arthroscopic autologous condrocyte transplantation: technical note

Abstract.We describe an arthroscopic surgical technique for tissue engineered cartilage grafting. A three-dimensional hyaluronic acid support is used for autologous chondrocyte culturing. The technique reduces morbidity of classic autologous implant and avoids open surgery and the use of a periosteal flap. The procedure includes the advantages of arthroscopic osteochondral grafting without donor site morbidity. With this technique is possible to reduce the patient morbidity, time and cost of surgery.

[1]  V. Goldberg,et al.  Hyaluronan‐based polymers in the treatment of osteochondral defects , 2000, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.

[2]  D Guidolin,et al.  Chondrocyte aggregation and reorganization into three-dimensional scaffolds. , 1999, Journal of biomedical materials research.

[3]  R Scapinelli,et al.  Hyaluronan-based biopolymers as delivery vehicles for bone-marrow-derived mesenchymal progenitors. , 2000, Journal of biomedical materials research.

[4]  V. Goldberg,et al.  Hyaluronic acid‐based polymers as cell carriers for tissue‐engineered repair of bone and cartilage , 1999, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.

[5]  D. Ogilvie-Harris,et al.  Arthroscopic management of the degenerative knee. , 1991, Arthroscopy : the journal of arthroscopic & related surgery : official publication of the Arthroscopy Association of North America and the International Arthroscopy Association.

[6]  E. Kastenbauer,et al.  Cartilage tissue engineering with novel nonwoven structured biomaterial based on hyaluronic acid benzyl ester. , 1998, Journal of biomedical materials research.