A novel acetylcholinesterase inhibitor and calcium channel blocker SCR-1693 improves Aβ25–35-impaired mouse cognitive function
暂无分享,去创建一个
L. Luo | Z. Yin | Xiaoliang Dong | Chunmei Wang | Aijing Bi | Wenji An | Rong Chen | Zhengping Zhang | Gaoyong Liao
[1] Desmond O'Neill,et al. Drug treatments in Alzheimer's disease. , 2016, Clinical medicine.
[2] Ling Chen,et al. Simvastatin prevents β-amyloid25–35-impaired neurogenesis in hippocampal dentate gyrus through α7nAChR-dependent cascading PI3K-Akt and increasing BDNF via reduction of farnesyl pyrophosphate , 2015, Neuropharmacology.
[3] A. Palmeri,et al. Behavioral assays with mouse models of Alzheimer's disease: practical considerations and guidelines. , 2014, Biochemical pharmacology.
[4] A. Sandoval,et al. Whole-cell patch-clamp recordings of Ca2+ currents from isolated neonatal mouse dorsal root ganglion (DRG) neurons. , 2014, Cold Spring Harbor protocols.
[5] Ling Chen,et al. Simvastatin Exerts Antiamnesic Effect in Aβ25‐35‐Injected Mice , 2014, CNS neuroscience & therapeutics.
[6] B. Harvey,et al. The interactions of azure B, a metabolite of methylene blue, with acetylcholinesterase and butyrylcholinesterase. , 2014, Toxicology and applied pharmacology.
[7] Abbas Ali Mahdi,et al. Therapeutics of Alzheimer's disease: Past, present and future , 2014, Neuropharmacology.
[8] J. Cummings,et al. Biomarker‐Driven Therapeutic Management of Alzheimer's Disease: Establishing the Foundations , 2013, Clinical pharmacology and therapeutics.
[9] M. D’Amelio,et al. Neuroprotective effects of donepezil against cholinergic depletion , 2013, Alzheimer's Research & Therapy.
[10] L. Zou,et al. Protective effect of xanthoceraside against β-amyloid-induced neurotoxicity in neuroblastoma SH-SY5Y cells , 2013, Journal of Asian natural products research.
[11] W. Klein,et al. Memantine Rescues Transient Cognitive Impairment Caused by High-Molecular-Weight Aβ Oligomers But Not the Persistent Impairment Induced by Low-Molecular-Weight Oligomers , 2013, The Journal of Neuroscience.
[12] V. Vasić,et al. Send Orders of Reprints at Reprints@benthamscience.net Acetylcholinesterase Inhibitors: Pharmacology and Toxicology , 2022 .
[13] I. Vetter,et al. Expression and Pharmacology of Endogenous Cav Channels in SH-SY5Y Human Neuroblastoma Cells , 2013, PloS one.
[14] S. H. Kim,et al. Blockade of Tau Hyperphosphorylation and Aβ1–42 Generation by the Aminotetrahydrofuran Derivative ANAVEX2-73, a Mixed Muscarinic and σ1 Receptor Agonist, in a Nontransgenic Mouse Model of Alzheimer’s Disease , 2013, Neuropsychopharmacology.
[15] J. Flores-Hernández,et al. Potassium Current Is Not Affected by Long-Term Exposure to Ghrelin or GHRP-6 in Somatotropes GC Cells , 2013, Journal of biophysics.
[16] Ling Chen,et al. Anti-amnesic effect of neurosteroid PREGS in Aβ25–35-injected mice through σ1 receptor- and α7nAChR-mediated neuroprotection , 2012, Neuropharmacology.
[17] N. Pivovarova,et al. Comparative Impact of Voltage-Gated Calcium Channels and NMDA Receptors on Mitochondria-Mediated Neuronal Injury , 2012, The Journal of Neuroscience.
[18] M. Sabbagh,et al. New Acetylcholinesterase Inhibitors for Alzheimer's Disease , 2011, International journal of Alzheimer's disease.
[19] J. Quinn,et al. Calcium channel blocking as a therapeutic strategy for Alzheimer's disease: the case for isradipine. , 2011, Biochimica et biophysica acta.
[20] G. Taglialatela,et al. Dysregulated phosphorylation of Ca2+/calmodulin‐dependent protein kinase II‐α in the hippocampus of subjects with mild cognitive impairment and Alzheimer’s disease , 2011, Journal of neurochemistry.
[21] T. Nabeshima,et al. Xanthoceraside attenuates amyloid β peptide25–35-induced learning and memory impairments in mice , 2011, Psychopharmacology.
[22] S. Marchal,et al. Time-course and regional analyses of the physiopathological changes induced after cerebral injection of an amyloid β fragment in rats. , 2011, The American journal of pathology.
[23] F. Lung,et al. Neuroprotection of paliperidone on SH-SY5Y cells against β-amyloid peptide25-35, N-methyl-4-phenylpyridinium ion, and hydrogen peroxide-induced cell death , 2011, Psychopharmacology.
[24] C. Volmar,et al. Selective Antihypertensive Dihydropyridines Lower Aβ Accumulation by Targeting both the Production and the Clearance of Aβ across the Blood-Brain Barrier , 2011, Molecular medicine.
[25] Christopher P. Chen,et al. Pharmacokinetic and Pharmacodynamic Properties of Cholinesterase Inhibitors Donepezil, Tacrine, and Galantamine in Aged and Young Lister Hooded Rats , 2011, Drug Metabolism and Disposition.
[26] J. Quinn,et al. L-type voltage-gated calcium channel blockade with isradipine as a therapeutic strategy for Alzheimer's disease , 2011, Neurobiology of Disease.
[27] G. Ginani,et al. Acute effects of donepezil in healthy young adults underline the fractionation of executive functioning , 2011, Journal of psychopharmacology.
[28] C. Jang,et al. Neuroprotective effects of Eucommia ulmoides Oliv. Bark on amyloid beta25–35-induced learning and memory impairments in mice , 2011, Neuroscience Letters.
[29] Huadong Zhou,et al. Nicotine exacerbates tau phosphorylation and cognitive impairment induced by amyloid-beta 25-35 in rats. , 2010, European journal of pharmacology.
[30] M. Sokabe,et al. DMXB (GTS‐21) ameliorates the cognitive deficits in beta amyloid 25–35 − injected mice through preventing the dysfunction of alpha7 nicotinic receptor , 2010, Journal of neuroscience research.
[31] Jincai Wang,et al. Daidzein induces MCF-7 breast cancer cell apoptosis via the mitochondrial pathway. , 2010, Annals of oncology : official journal of the European Society for Medical Oncology.
[32] V. Tancredi,et al. Phosphorylation Changes of CaMKII, ERK1/2, PKB/Akt Kinases and CREB Activation During Early Long-Term Potentiation at Schaffer Collateral-CA1 Mouse Hippocampal Synapses , 2010, Neurochemical Research.
[33] G. Du,et al. Protective effect of stilbenes containing extract-fraction from Cajanus cajan L. on Aβ25–35-induced cognitive deficits in mice , 2009, Neuroscience Letters.
[34] Jin-Tai Yu,et al. Calcium dysregulation in Alzheimer's disease: From mechanisms to therapeutic opportunities , 2009, Progress in Neurobiology.
[35] Xavier Barril,et al. Tacripyrines, the first tacrine-dihydropyridine hybrids, as multitarget-directed ligands for the treatment of Alzheimer's disease. , 2009, Journal of medicinal chemistry.
[36] M. Giovannini,et al. Cholinesterase inhibitors and beyond. , 2009, Current Alzheimer research.
[37] Ilya Bezprozvanny,et al. Neuronal calcium mishandling and the pathogenesis of Alzheimer's disease , 2008, Trends in Neurosciences.
[38] Kim N. Green,et al. Linking Calcium to Aβ and Alzheimer's Disease , 2008, Neuron.
[39] Maurizio Recanatini,et al. Multi-target-directed ligands to combat neurodegenerative diseases. , 2008, Journal of medicinal chemistry.
[40] B. Seltzer,et al. Donepezil: an update , 2007, Expert opinion on pharmacotherapy.
[41] B. Pakkenberg,et al. A neural cell adhesion molecule–derived peptide reduces neuropathological signs and cognitive impairment induced by Aβ25-35 , 2007, Neuroscience.
[42] J. Ieni,et al. The anti‐amnesic and neuroprotective effects of donepezil against amyloid β25‐35 peptide‐induced toxicity in mice involve an interaction with the σ1 receptor , 2006, British journal of pharmacology.
[43] J. Lucas,et al. Full Reversal of Alzheimer's Disease-Like Phenotype in a Mouse Model with Conditional Overexpression of Glycogen Synthase Kinase-3 , 2006, The Journal of Neuroscience.
[44] A. Akaike,et al. Up-regulation of nicotinic acetylcholine receptors by central-type acetylcholinesterase inhibitors in rat cortical neurons. , 2005, European journal of pharmacology.
[45] H. Ogura,et al. Protective effect of donepezil against Aβ(1-40) neurotoxicity in rat septal neurons , 2005, Brain Research.
[46] P. Ghisdal,et al. Intraneuronal amyloid‐β1‐42 production triggered by sustained increase of cytosolic calcium concentration induces neuronal death , 2004, Journal of neurochemistry.
[47] M. Onufriev,et al. Amyloid-β(25–35)-induced memory impairments correlate with cell loss in rat hippocampus , 2004, Physiology & Behavior.
[48] M. Onufriev,et al. Single intracerebroventricular administration of amyloid-beta (25–35) peptide induces impairment in short-term rather than long-term memory in rats , 2003, Brain Research Bulletin.
[49] C. Herron,et al. A beta 25-35-induced depression of long-term potentiation in area CA1 in vivo and in vitro is attenuated by verapamil. , 2003, Journal of neurophysiology.
[50] F. LaFerla. Calcium dyshomeostasis and intracellular signalling in alzheimer's disease , 2002, Nature Reviews Neuroscience.
[51] M. Yamakage,et al. Calcium channels — basic aspects of their structure, function and gene encoding; anesthetic action on the channels — a review , 2002, Canadian journal of anaesthesia = Journal canadien d'anesthesie.
[52] D. K. Berg,et al. Voltage-Gated Channels Block Nicotinic Regulation of CREB Phosphorylation and Gene Expression in Neurons , 2001, Neuron.
[53] T. Aosaki,et al. Deficiency of presenilin‐1 increases calcium‐dependent vulnerability of neurons to oxidative stress in vitro , 2001, Journal of neurochemistry.
[54] D. Small,et al. Alzheimer's disease and Aβ toxicity: from top to bottom , 2001, Nature Reviews Neuroscience.
[55] R. Doody,et al. Chronic Donepezil Treatment Is Associated with Slowed Cognitive Decline in Alzheimer’s Disease , 2001, Dementia and Geriatric Cognitive Disorders.
[56] H. Shibasaki,et al. α7 Nicotinic Receptor Transduces Signals to Phosphatidylinositol 3-Kinase to Block A β-Amyloid-induced Neurotoxicity* , 2001, The Journal of Biological Chemistry.
[57] H. Sugimoto,et al. Donepezil hydrochloride (E2020) and other acetylcholinesterase inhibitors. , 2000, Current medicinal chemistry.
[58] A. Privat,et al. In vitro aggregation facilitates β-amyloid peptide-(25–35)-induced amnesia in the rat , 1997 .
[59] A. Privat,et al. Amnesia induced in mice by centrally administered β-amyloid peptides involves cholinergic dysfunction , 1996, Brain Research.
[60] Alcino J. Silva,et al. Deficient long-term memory in mice with a targeted mutation of the cAMP-responsive element-binding protein , 1994, Cell.
[61] B. K. Park,et al. An investigation into the formation of stable, protein-reactive and cytotoxic metabolites from tacrine in vitro. Studies with human and rat liver microsomes. , 1993, Biochemical pharmacology.
[62] T. Narahashi,et al. Two types of high voltage-activated calcium channels in SH-SY5Y human neuroblastoma cells , 1993, Brain Research.
[63] P. Kostyuk,et al. Calcium currents in aged rat dorsal root ganglion neurones. , 1993, The Journal of physiology.
[64] R. Nicoll,et al. An essential role for postsynaptic calmodulin and protein kinase activity in long-term potentiation , 1989, Nature.
[65] K. Courtney,et al. A new and rapid colorimetric determination of acetylcholinesterase activity. , 1961, Biochemical pharmacology.
[66] M. Dixon. The determination of enzyme inhibitor constants. , 1953, The Biochemical journal.
[67] Q. Tian,et al. Novel multipotent AChEI-CCB attenuates hyperhomocysteinemia-induced memory deficits and Neuropathologies in rats. , 2014, Journal of Alzheimer's disease : JAD.
[68] Patrick G Kehoe,et al. Calcium channel blockers and Alzheimer's disease: potential relevance in treatment strategies of metabolic syndrome. , 2012, Journal of Alzheimer's disease : JAD.
[69] D. Selkoe. Alzheimer's disease. , 2011, Cold Spring Harbor perspectives in biology.
[70] M. Sabbagh,et al. Donepezil: potential neuroprotective and disease-modifying effects. , 2008, Expert opinion on drug metabolism & toxicology.
[71] B. Pakkenberg,et al. A neural cell adhesion molecule-derived peptide reduces neuropathological signs and cognitive impairment induced by Abeta25-35. , 2007, Neuroscience.
[72] A. Privat,et al. In vitro aggregation facilities beta-amyloid peptide-(25-35)-induced amnesia in the rat. , 1997, European journal of pharmacology.
[73] B. Pitt. Psychopharmacology , 1968, Mental Health.