Five-Year Cost-effectiveness of the Multidisciplinary Risk Assessment and Management Programme–Diabetes Mellitus (RAMP-DM)

OBJECTIVE To estimate the cost-effectiveness of the multidisciplinary Risk Assessment and Management Programme–Diabetes Mellitus (RAMP-DM) in primary care patients with type 2 diabetes in comparison with usual primary care in a cohort with 5 years’ follow-up. RESEARCH DESIGN AND METHODS We conducted a prospective cohort study among 17,140 propensity score–matched participants in RAMP-DM and those under usual primary care. The effectiveness measures were cumulative incidences of complications and all-cause mortality over 5 years. In a bottom-up approach, we estimated the program costs of RAMP-DM and health service utilization from the public health service provider’s perspective. The RAMP-DM program costs included the setup costs, ongoing intervention costs, and central administrative costs. We calculated the incremental cost-effectiveness ratio by dividing the incremental costs by the incremental effectiveness of the RAMP-DM group compared with those of the usual-care group. RESULTS There were significantly lower cumulative incidences of individual on any complications (15.34% vs. 28.65%, P < 0.001) and all-cause mortality (7.96% vs. 21.35%, P < 0.001) in the RAMP-DM group compared with the usual-care group. The mean program cost of RAMP-DM was 157 U.S. dollars (range 66–209) per participant over 5 years. The costs of health service utilization among participants in RAMP-DM group was 7,451 USD less than that of the usual-care group, resulting in a net savings of 7,294 USD per individual. CONCLUSIONS RAMP-DM added to usual primary care was a cost-saving intervention in managing diabetes in patients over 5 years. These findings support the integration of RAMP-DM as part of routine primary care for all patients with diabetes.

[1]  Jiang He,et al.  Prevalence and control of diabetes in Chinese adults. , 2013, JAMA.

[2]  Sharon A. Brown Interventions to Promote Diabetes Self-Management: State of the Science , 1999, The Diabetes educator.

[3]  Within-trial cost-effectiveness of lifestyle intervention or metformin for the primary prevention of type 2 diabetes. , 2003, Diabetes care.

[4]  S. McGhee,et al.  Long-term effects of the multidisciplinary risk assessment and management program for patients with diabetes mellitus (RAMP-DM): a population-based cohort study , 2015, Cardiovascular Diabetology.

[5]  J. Cade,et al.  Group based training for self-management strategies in people with type 2 diabetes mellitus. , 2005, The Cochrane database of systematic reviews.

[6]  H. Beck-Nielsen,et al.  Structured personal care of type 2 diabetes: a 19 year follow-up of the study Diabetes Care in General Practice (DCGP) , 2013, Diabetologia.

[7]  E. Fisher,et al.  National Standards for Diabetes Self-Management Education and Support , 2012, The Diabetes educator.

[8]  Morton B. Brown,et al.  The 10-year cost-effectiveness of lifestyle intervention or metformin for diabetes prevention: An intent-to-treat analysis of the DPP/DPPOS , 2013 .

[9]  E. Luman,et al.  A National Effort to Prevent Type 2 Diabetes: Participant-Level Evaluation of CDC’s National Diabetes Prevention Program , 2017, Diabetes Care.

[10]  Mei-Yen Chen,et al.  Effectiveness of a health promotion programme for farmers and fishermen with type-2 diabetes in Taiwan. , 2011, Journal of advanced nursing.

[11]  D L Sackett,et al.  An assessment of clinically useful measures of the consequences of treatment. , 1988, The New England journal of medicine.

[12]  R. Glasgow,et al.  Intervention costs and cost-effectiveness for a multiple-risk-factor diabetes self-management trial for Latinas: economic analysis of ¡Viva Bien! , 2011, Translational behavioral medicine.

[13]  Ping Zhang,et al.  The 10-Year Cost-Effectiveness of Lifestyle Intervention or Metformin for Diabetes Prevention , 2012, Diabetes Care.

[14]  J. Jukema,et al.  Stratified Patient-Centered Care in Type 2 Diabetes , 2013, Diabetes Care.

[15]  K Khunti,et al.  Delivering the diabetes education and self management for ongoing and newly diagnosed (DESMOND) programme for people with newly diagnosed type 2 diabetes: cost effectiveness analysis , 2010, BMJ : British Medical Journal.

[16]  K. Khunti,et al.  Cost-effectiveness of intensive multifactorial treatment compared with routine care for individuals with screen-detected Type 2 diabetes: analysis of the ADDITION-UK cluster-randomized controlled trial , 2015, Diabetic medicine : a journal of the British Diabetic Association.

[17]  G. Hitman,et al.  Cost-effectiveness of primary prevention of cardiovascular disease with atorvastatin in type 2 diabetes: results from the Collaborative Atorvastatin Diabetes Study (CARDS) , 2007, Diabetologia.

[18]  W. Katon,et al.  Cost-effectiveness of a multicondition collaborative care intervention: a randomized controlled trial. , 2012, Archives of general psychiatry.

[19]  E. Guallar,et al.  Meta-Analysis of Randomized Educational and Behavioral Interventions in Type 2 Diabetes , 2003, The Diabetes educator.

[20]  E. Wan,et al.  Five-Year Effectiveness of the Multidisciplinary Risk Assessment and Management Programme–Diabetes Mellitus (RAMP-DM) on Diabetes-Related Complications and Health Service Uses—A Population-Based and Propensity-Matched Cohort Study , 2017, Diabetes Care.

[21]  C. Lawton Highlights of the 2003 Clinical Practice Guidelines for the prevention and management of diabetes in Canada. , 2004, CANNT journal = Journal ACITN.

[22]  Jing Wang,et al.  2017 National Standards for Diabetes Self-Management Education and Support , 2017, Diabetes Care.

[23]  M. Maislos,et al.  Multidisciplinary approach to patients with poorly controlled type 2 diabetes mellitus: a prospective, randomized study , 2004, Acta Diabetologica.

[24]  Engin Yilmaz,et al.  Effect of a French experiment of team work between general practitioners and nurses on efficacy and cost of type 2 diabetes patients care. , 2010, Health policy.

[25]  Paul Fenn,et al.  Cost effectiveness of an intensive blood glucose control policy in patients with type 2 diabetes: economic analysis alongside randomised controlled trial (UKPDS 41) , 2000, BMJ : British Medical Journal.

[26]  J. Chan,et al.  Comprehensive risk assessments of diabetic patients from seven Asian countries: The Joint Asia Diabetes Evaluation (JADE) program * , 2011, Journal of diabetes.

[27]  Kamlesh Khunti,et al.  Effect of early intensive multifactorial therapy on 5-year cardiovascular outcomes in individuals with type 2 diabetes detected by screening (ADDITION-Europe): a cluster-randomised trial , 2011, The Lancet.

[28]  M. Johannesson,et al.  Cost-effectiveness of intense insulin treatment after acute myocardial infarction in patients with diabetes mellitus; results from the DIGAMI study. , 2000, European heart journal.

[29]  Eva L. H. Tsui,et al.  Evaluation of the quality of care of a multi-disciplinary risk factor assessment and management programme (RAMP) for diabetic patients , 2012, BMC Family Practice.

[30]  S. McGhee,et al.  Effectiveness of the multidisciplinary Risk Assessment and Management Program for Patients with Diabetes Mellitus (RAMP-DM) for diabetic microvascular complications: A population-based cohort study. , 2016, Diabetes & metabolism.

[31]  C. Schmid,et al.  Self-management education for adults with type 2 diabetes: a meta-analysis of the effect on glycemic control. , 2002, Diabetes care.

[32]  V. Lee,et al.  Cost of Type 2 Diabetes mellitus in Hong Kong Chinese. , 2007, International journal of clinical pharmacology and therapeutics.

[33]  Eva L. H. Tsui,et al.  Effects of Patient Empowerment Programme (PEP) on Clinical Outcomes and Health Service Utilization in Type 2 Diabetes Mellitus in Primary Care: An Observational Matched Cohort Study , 2014, PloS one.

[34]  W. Assendelft,et al.  Interventions to improve the management of diabetes in primary care, outpatient, and community settings: a systematic review. , 2001, Diabetes care.

[35]  L. Mion,et al.  Physician–nurse practitioner teams in chronic disease management: the impact on costs, clinical effectiveness, and patients' perception of care , 2003, Journal of interprofessional care.

[36]  C. Fung,et al.  Effects of the Multidisciplinary Risk Assessment and Management Program for Patients with Diabetes Mellitus (RAMP-DM) on biomedical outcomes, observed cardiovascular events and cardiovascular risks in primary care: a longitudinal comparative study , 2014, Cardiovascular Diabetology.