The DNA methylation drift of the atherosclerotic aorta increases with lesion progression

[1]  S. Stepaniants,et al.  A Gene Expression Signature That Classifies Human Atherosclerotic Plaque by Relative Inflammation Status , 2011, Circulation. Cardiovascular genetics.

[2]  D. Peng,et al.  The effects of myocyte enhancer factor 2A gene on the proliferation, migration and phenotype of vascular smooth muscle cells , 2012, Cell biochemistry and function.

[3]  K. Abromeit Music Received , 2023, Notes.

[4]  F. Villarroya,et al.  Peroxisome Proliferator-activated Receptor α (PPARα) Induces PPARγ Coactivator 1α (PGC-1α) Gene Expression and Contributes to Thermogenic Activation of Brown Fat , 2011, The Journal of Biological Chemistry.

[5]  S. George,et al.  An essential role for platelet-derived growth factor in neointima formation in human saphenous vein in vitro. , 1996, Atherosclerosis.

[6]  K. Airenne,et al.  Local hypomethylation in atherosclerosis found in rabbit ec-sod gene. , 1999, Arteriosclerosis, thrombosis, and vascular biology.

[7]  Alfonso Valencia,et al.  Distinct DNA methylomes of newborns and centenarians , 2012, Proceedings of the National Academy of Sciences.

[8]  P. E. Newman Can reduced folic acid and vitamin B12 levels cause deficient DNA methylation producing mutations which initiate atherosclerosis? , 1999, Medical hypotheses.

[9]  S. Zaina Unraveling the DNA methylome of atherosclerosis , 2014, Current opinion in lipidology.

[10]  K. Mitomo,et al.  Involvement of a NF-kappa B-like transcription factor in the activation of the interleukin-6 gene by inflammatory lymphokines , 1990, Molecular and cellular biology.

[11]  Christopher K. Glass,et al.  The peroxisome proliferator-activated receptor-γ is a negative regulator of macrophage activation , 1998, Nature.

[12]  Björn Rotter,et al.  SuperTAG Methylation-specific Digital Karyotyping Reveals Uremia-induced Epigenetic Dysregulation of Atherosclerosis-Related Genes , 2012, Circulation. Cardiovascular genetics.

[13]  M. Esteller,et al.  DNA Methylation Map of Human Atherosclerosis , 2014, Circulation. Cardiovascular genetics.

[14]  K. Hochedlinger,et al.  Chromatin dynamics during cellular reprogramming , 2013, Nature.

[15]  C. Gieger,et al.  DNA methylation and body-mass index: a genome-wide analysis , 2014, The Lancet.

[16]  A. Conesa,et al.  Differential expression in RNA-seq: a matter of depth. , 2011, Genome research.

[17]  J. Ordovás,et al.  Epigenetics and cardiovascular disease , 2010, Nature Reviews Cardiology.

[18]  Mark T Bedford,et al.  Arginine methyltransferase CARM1 is a promoter‐specific regulator of NF‐κB‐dependent gene expression , 2005, The EMBO journal.

[19]  J. Flanagan,et al.  An epigenetic role for noncoding RNAs and intragenic DNA methylation , 2007, Genome Biology.

[20]  Shu-ren Wang,et al.  Hypermethylation of estrogen receptor-alpha gene in atheromatosis patients and its correlation with homocysteine. , 2009, Pathophysiology : the official journal of the International Society for Pathophysiology.

[21]  Gary D Bader,et al.  Integrative pathway dissection of molecular mechanisms of moxLDL-induced vascular smooth muscle phenotype transformation , 2013, BMC Cardiovascular Disorders.

[22]  N. Maeda,et al.  Spontaneous hypercholesterolemia and arterial lesions in mice lacking apolipoprotein E. , 1992, Science.

[23]  W. Reik Stability and flexibility of epigenetic gene regulation in mammalian development , 2007, Nature.

[24]  E. Topol,et al.  Mutation of MEF2A in an Inherited Disorder with Features of Coronary Artery Disease , 2003, Science.

[25]  J. Kumar,et al.  Detection of altered global DNA methylation in coronary artery disease patients. , 2008, DNA and cell biology.

[26]  L. Liang,et al.  Epigenome-Wide Association Study of Fasting Blood Lipids in the Genetics of Lipid-Lowering Drugs and Diet Network Study , 2014, Circulation.

[27]  K. Williams,et al.  Atherosclerosis--an inflammatory disease. , 1999, The New England journal of medicine.

[28]  J. Dunn,et al.  Flow-dependent epigenetic DNA methylation regulates endothelial gene expression and atherosclerosis. , 2014, The Journal of clinical investigation.

[29]  M. Esteller,et al.  Validation of a DNA methylation microarray for 450,000 CpG sites in the human genome , 2011, Epigenetics.

[30]  Hemant K. Tiwari,et al.  Epigenome-Wide Association Study of Fasting Measures of Glucose, Insulin, and HOMA-IR in the Genetics of Lipid Lowering Drugs and Diet Network Study , 2014, Diabetes.

[31]  M. Reilly,et al.  Genetic Basis of Atherosclerosis: Insights From Mice and Humans , 2012, Circulation research.

[32]  Richard Durbin,et al.  Sequence analysis Fast and accurate short read alignment with Burrows – Wheeler transform , 2009 .

[33]  P. Jin,et al.  Integrating DNA methylation dynamics into a framework for understanding epigenetic codes , 2014, BioEssays : news and reviews in molecular, cellular and developmental biology.

[34]  W. Kong,et al.  Homocysteine activates vascular smooth muscle cells by DNA demethylation of platelet-derived growth factor in endothelial cells. , 2012, Journal of molecular and cellular cardiology.

[35]  Robert A. Waterland,et al.  Transposable Elements: Targets for Early Nutritional Effects on Epigenetic Gene Regulation , 2003, Molecular and Cellular Biology.

[36]  Huidong Shi,et al.  Inhibiting DNA Methylation by 5-Aza-2'-deoxycytidine ameliorates atherosclerosis through suppressing macrophage inflammation. , 2014, Endocrinology.

[37]  D. Reinberg,et al.  Prdm3 and Prdm16 are H3K9me1 Methyltransferases Required for Mammalian Heterochromatin Integrity , 2012, Cell.

[38]  P. Goldschmidt-Clermont,et al.  Inactivation of Monocarboxylate Transporter MCT3 by DNA Methylation in Atherosclerosis , 2005, Circulation.

[39]  Xiao Zhang,et al.  Comparison of Beta-value and M-value methods for quantifying methylation levels by microarray analysis , 2010, BMC Bioinformatics.

[40]  Mark Groudine,et al.  Intragenic DNA methylation alters chromatin structure and elongation efficiency in mammalian cells , 2004, Nature Structural &Molecular Biology.

[41]  Luigi Ferrucci,et al.  Abundant Quantitative Trait Loci Exist for DNA Methylation and Gene Expression in Human Brain , 2010, PLoS genetics.