The Transgenic Rabbit as Model for Human Diseases and as a Source of Biologically Active Recombinant Proteins
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Z. Bősze | J. Carnwath | H. Niemann | L. Hiripi | Z. Bösze
[1] G. Brem,et al. Expression and characterization of functional recombinant bovine follicle‐stimulating hormone (boFSHα/β) produced in the milk of transgenic rabbits , 2002, Molecular reproduction and development.
[2] G. Pfeifer,et al. Reduced expression and increased CpG dinucleotide methylation of the rat APOBEC-1 promoter in transgenic rabbits. , 2002, Biochimica et biophysica acta.
[3] L. Houdebine. The methods to generate transgenic animals and to control transgene expression. , 2002, Journal of biotechnology.
[4] J. Robbins,et al. Transgenic rabbits expressing mutant essential light chain do not develop hypertrophic cardiomyopathy. , 2002, Journal of molecular and cellular cardiology.
[5] J. Renard,et al. Cloned rabbits produced by nuclear transfer from adult somatic cells , 2002, Nature Biotechnology.
[6] Yifan Dai,et al. Targeted disruption of the α1,3-galactosyltransferase gene in cloned pigs , 2002, Nature Biotechnology.
[7] Huijun Sun,et al. Enhanced Atherosclerosis in Lp(a) WHHL Transgenic Rabbits , 2001, Annals of the New York Academy of Sciences.
[8] Huijun Sun,et al. Overexpression of Lipoprotein Lipase in Transgenic Rabbits Inhibits Diet-induced Hypercholesterolemia and Atherosclerosis* , 2001, The Journal of Biological Chemistry.
[9] Xuwen Peng,et al. Reinitiated expression of EJras transgene in targeted epidermal cells of transgenic rabbits by cottontail rabbit papillomavirus infection. , 2001, Cancer letters.
[10] J W Larrick,et al. Producing proteins in transgenic plants and animals. , 2001, Current opinion in biotechnology.
[11] M. Quiñones,et al. Tissue Doppler Imaging Consistently Detects Myocardial Abnormalities in Patients With Hypertrophic Cardiomyopathy and Provides a Novel Means for an Early Diagnosis Before and Independently of Hypertrophy , 2001, Circulation.
[12] L. V. van Zutphen,et al. Mapping of a QTL for serum HDL cholesterol in the rabbit using AFLP technology. , 2001, The Journal of heredity.
[13] J. Smeitink,et al. Enzyme therapy for Pompe disease with recombinant human α-glucosidase from rabbit milk , 2001, Journal of Inherited Metabolic Disease.
[14] G. Hadlaczky. Satellite DNA-based artificial chromosomes for use in gene therapy. , 2001, Current opinion in molecular therapeutics.
[15] C. Galet,et al. Expression of a single βα chain protein of equine LH/CG in milk of transgenic rabbits and its biological activity , 2001, Molecular and Cellular Endocrinology.
[16] J. Caillaud,et al. Increased levels of high-density lipoprotein cholesterol are ineffective in inhibiting the development of immune responses to oxidized low-density lipoprotein and atherosclerosis in transgenic rabbits expressing human apolipoprotein (apo) A-I with severe hypercholesterolaemia. , 2001, Clinical science.
[17] K. Garber. rFactor VIII deficit questioned , 2000, Nature Biotechnology.
[18] A. Dove. Milking the genome for profit , 2000, Nature Biotechnology.
[19] M. Quiñones,et al. Tissue Doppler Imaging Consistently Detects Myocardial Contraction and Relaxation Abnormalities, Irrespective of Cardiac Hypertrophy, in a Transgenic Rabbit Model of Human Hypertrophic Cardiomyopathy , 2000, Circulation.
[20] A. Vulto,et al. Recombinant human α-glucosidase from rabbit milk in Pompe patients , 2000, The Lancet.
[21] Jianglin Fan,et al. Transgenic rabbits expressing human lipoprotein lipase. , 2000 .
[22] Jianglin Fan,et al. Cholesterol-fed and transgenic rabbit models for the study of atherosclerosis. , 2000, Journal of atherosclerosis and thrombosis.
[23] T. Raju,et al. Species-specific variation in glycosylation of IgG: evidence for the species-specific sialylation and branch-specific galactosylation and importance for engineering recombinant glycoprotein therapeutics. , 2000, Glycobiology.
[24] Jianglin Fan,et al. Transgenic Rabbits Expressing Human Apolipoprotein(a) as a Useful Model for the Study of Lipoprotein(a) a , 2000, Annals of the New York Academy of Sciences.
[25] JeffreyRobbins,et al. Genetic Manipulation of the Rabbit Heart via Transgenesis , 2000 .
[26] J. Caillaud,et al. Paraoxonase activity is reduced by a pro-atherosclerotic diet in rabbits. , 2000, Biochemical and biophysical research communications.
[27] A J Marian,et al. A transgenic rabbit model for human hypertrophic cardiomyopathy. , 1999, The Journal of clinical investigation.
[28] J. de la Fuente,et al. Transgenic rabbits for the production of biologically-active recombinant proteins in the milk. , 1999, Genetic analysis : biomolecular engineering.
[29] C. Chichester,et al. Articular collagen degradation in the Hulth-Telhag model of osteoarthritis. , 1999, Osteoarthritis and cartilage.
[30] Nathan C Frey,et al. The 2.3 kb smooth muscle myosin heavy chain promoter directs gene expression into the vascular system of transgenic mice and rabbits. , 1999, Cardiovascular research.
[31] N. Rudolph. Biopharmaceutical production in transgenic livestock. , 1999, Trends in biotechnology.
[32] J. Kreider,et al. Development of keratoacanthomas and squamous cell carcinomas in transgenic rabbits with targeted expression of EJras oncogene in epidermis. , 1999, The American journal of pathology.
[33] Jianglin Fan,et al. Transgenic rabbit models for biomedical research: Current status, basic methods and future perspectives , 1999, Pathology international.
[34] H. Niemann,et al. Expression of human blood clotting factor VIII in the mammary gland of transgenic sheep , 1999, Transgenic Research.
[35] B. Malassagne,et al. Association of the 5′ HS4 sequence of the chicken β‐globin locus control region with human EF1α gene promoter induces ubiquitous and high expression of human CD55 and CD59 cDNAs in transgenic rabbits , 1999, Transgenic Research.
[36] G. Brem,et al. Species-specific alternative splicing of transgenic RNA in the mammary glands of pigs, rabbits, and mice. , 1999, Biochemical and biophysical research communications.
[37] M. Sheppard,et al. In vivo transfer of interleukin-1 receptor antagonist gene in osteoarthritic rabbit knee joints: prevention of osteoarthritis progression. , 1999, The American journal of pathology.
[38] R. Krauss,et al. Overexpression of human hepatic lipase and ApoE in transgenic rabbits attenuates response to dietary cholesterol and alters lipoprotein subclass distributions. , 1999, Arteriosclerosis, thrombosis, and vascular biology.
[39] J. Hoeg,et al. Transgenic rabbits as models for atherosclerosis research. , 1999, Journal of lipid research.
[40] G. Brem,et al. Human nerve growth factor beta (hNGF‐β): mammary gland specific expression and production in transgenic rabbits , 1999, FEBS letters.
[41] E. Wolf,et al. Stable Production of Human Insulin-like Growth Factor 1 (IGF-1) in the Milk of Hemi- and Homozygous Transgenic Rabbits Over Several Generations , 1998, Transgenic Research.
[42] F. Bosch,et al. Transgenic rabbits overexpressing growth hormone develop acromegaly and diabetes mellitus , 1998, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
[43] D. Ecker,et al. Inhibition of Human Immunodeficiency Virus Type 1 Infection in SCID-hu Thy/Liv Mice by the G-Quartet-Forming Oligonucleotide, ISIS 5320 , 1998, Antimicrobial Agents and Chemotherapy.
[44] C. Mckee,et al. Production of biologically active salmon calcitonin in the milk of transgenic rabbits , 1998, Nature Biotechnology.
[45] J. Taylor,et al. Increased expression of apolipoprotein E in transgenic rabbits results in reduced levels of very low density lipoproteins and an accumulation of low density lipoproteins in plasma. , 1998, The Journal of clinical investigation.
[46] E. Rubin,et al. Apolipoprotein(a) Yeast Artificial Chromosome Transgenic Rabbits , 1998, The Journal of Biological Chemistry.
[47] P. Denéfle,et al. Endothelial derived vasorelaxation is impaired in human APO A-I transgenic rabbits. , 1997, Biochemical and biophysical research communications.
[48] F. Gwazdauskas,et al. Transgenic pigs produce functional human factor VIII in milk , 1997, Nature Biotechnology.
[49] R. Mahley,et al. Apolipoprotein E2 Transgenic Rabbits , 1997, The Journal of Biological Chemistry.
[50] L. Houdebine,et al. Recombinant human extracellular superoxide dismutase produced in milk of transgenic rabbits , 1997, Transgenic Research.
[51] R. Paleyanda,et al. Vitamin K-Dependent Protein Production in Transgenic Animals , 1997, Thrombosis and Haemostasis.
[52] L. Alhonen,et al. Expression of bovine beta-lactoglobulin/human erythropoietin fusion protein in the milk of transgenic mice and rabbits. , 1997, European journal of biochemistry.
[53] P. Denéfle,et al. Transgenic rabbits expressing human apolipoprotein A-I in the liver. , 1996, Arteriosclerosis, thrombosis, and vascular biology.
[54] L. Schoonjans,et al. Pluripotential rabbit embryonic stem (ES) cells are capable of forming overt coat color chimeras following injection into blastocysts , 1996, Molecular reproduction and development.
[55] R. F. Hoyt,et al. Overexpression of lecithin:cholesterol acyltransferase in transgenic rabbits prevents diet-induced atherosclerosis. , 1996, Proceedings of the National Academy of Sciences of the United States of America.
[56] P. Denéfle,et al. Inhibition of atherosclerosis development in cholesterol-fed human apolipoprotein A-I-transgenic rabbits. , 1996, Circulation.
[57] G. Brem,et al. YAC transgenesis in farm animals: Rescue of albinism in rabbits , 1996, Molecular reproduction and development.
[58] E. Cozzi,et al. Production of pigs transgenic for human regulators of complement activation using YAC technology. , 1996, Transplantation proceedings.
[59] R. F. Hoyt,et al. Lecithin:Cholesterol Acyltransferase Overexpression Generates Hyperalpha-lipoproteinemia and a Nonatherogenic Lipoprotein Pattern in Transgenic Rabbits (*) , 1996, The Journal of Biological Chemistry.
[60] Laurent Duret,et al. Phylogenetic position of the order Lagomorpha (rabbits, hares and allies) , 1996, Nature.
[61] L. Chan,et al. Transgenic rabbits with the integrated human 15‐lipoxygenase gene driven by a lysozyme promoter: macrophage‐specific expression and variable positional specificity of the transgenic enzyme , 1995, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
[62] R. Krauss,et al. Overexpression of human apolipoprotein B-100 in transgenic rabbits results in increased levels of LDL and decreased levels of HDL. , 1995, Arteriosclerosis, thrombosis, and vascular biology.
[63] K L Knight,et al. Rabbit monoclonal antibodies: generating a fusion partner to produce rabbit-rabbit hybridomas. , 1995, Proceedings of the National Academy of Sciences of the United States of America.
[64] J. Taylor,et al. Apolipoprotein B mRNA-editing protein induces hepatocellular carcinoma and dysplasia in transgenic animals. , 1995, Proceedings of the National Academy of Sciences of the United States of America.
[65] M. Baranyi,et al. New data on the proteins of rabbit (Oryctolagus cuniculus) milk. , 1995, Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology.
[66] M. Mehtali,et al. Human immunodeficiency virus type 1 infection of human CD4-transgenic rabbits. , 1995, The Journal of general virology.
[67] J. de la Fuente,et al. Transgenic rabbits as bioreactors for the production of human growth hormone. , 1995, Journal of biotechnology.
[68] T. Kindt,et al. Developmental and tissue‐specific expression of human CD4 in transgenic rabbits , 1995, Molecular reproduction and development.
[69] C. Tunyaplin,et al. Lymphoid and non-lymphoid tumors in E kappa-myc transgenic rabbits. , 1994, Leukemia.
[70] E. Wolf,et al. Expression of synthetic cDNA sequences encoding human insulin-like growth factor-1 (IGF-1) in the mammary gland of transgenic rabbits. , 1994, Gene.
[71] C. Pinkert,et al. Liver, renal and subcutaneous histopathology in PEPCK-bGH transgenic pigs , 1994, Transgenic Research.
[72] J. Taylor,et al. Overexpression of hepatic lipase in transgenic rabbits leads to a marked reduction of plasma high density lipoproteins and intermediate density lipoproteins. , 1994, Proceedings of the National Academy of Sciences of the United States of America.
[73] R. Moreadith,et al. Derivation and characterization of putative pluripotential embryonic stem cells from preimplantation rabbit embryos , 1993, Molecular reproduction and development.
[74] J. Robl,et al. Effect of milking frequency oh collection of milk from nursing New Zealand white rabbits 1 , 1993 .
[75] J. Kreider,et al. Papillomas and carcinomas in transgenic rabbits carrying EJ-ras DNA and cottontail rabbit papillomavirus DNA , 1993, Journal of virology.
[76] Merrill Overturf,et al. In vivo model systems: the choice of the experimental animal model for analysis of lipoproteins and atherosclerosis , 1992 .
[77] M. I. Prokof'ev,et al. Transgenic rabbits with antisense RNA gene targeted at adenovirus H5 , 1991 .
[78] H. Lenz,et al. Genes encoding a mouse monoclonal antibody are expressed in transgenic mice, rabbits and pigs. , 1991, Gene.
[79] J. Schleich,et al. The complete sequence of the human beta-myosin heavy chain gene and a comparative analysis of its product. , 1990, Genomics.
[80] C. Caskey,et al. Antisense RNA production in transgenic mice , 1990, Somatic cell and molecular genetics.
[81] K. Bürki,et al. Rabbit β-Casein Promoter Directs Secretion of Human Interleukin-2 into the Milk of Transgenic Rabbits , 1990, Bio/Technology.
[82] E. Boerwinkle,et al. Defects in the low density lipoprotein receptor gene affect lipoprotein (a) levels: multiplicative interaction of two gene loci associated with premature atherosclerosis. , 1989, Proceedings of the National Academy of Sciences of the United States of America.
[83] C. Woodworth,et al. Induction of human cervical squamous cell carcinoma by sequential transfection with human papillomavirus 16 DNA and viral Harvey ras. , 1989, Oncogene.
[84] J. de Vente,et al. Tissue-specific expression and dietary regulation of a chimeric phosphoenolpyruvate carboxykinase/bovine growth hormone gene in transgenic mice. , 1988, The Journal of biological chemistry.
[85] V. Oi,et al. Transgenic rabbits with lymphocytic leukemia induced by the c-myc oncogene fused with the immunoglobulin heavy chain enhancer. , 1988, Proceedings of the National Academy of Sciences of the United States of America.
[86] J. Schneider,et al. Human papillomavirus type 16 DNA cooperates with activated ras in transforming primary cells. , 1987, The EMBO journal.
[87] B. Lewis,et al. Hereditary Hyperlipidemia in the Rabbit Due to Overproduction of Lipoproteins: I. Biochemical Studies , 1987, Arteriosclerosis.
[88] R. Palmiter,et al. Production of transgenic rabbits, sheep and pigs by microinjection , 1985, Nature.
[89] M. Yaniv,et al. Genomic structure of the cottontail rabbit (Shope) papillomavirus. , 1985, Proceedings of the National Academy of Sciences of the United States of America.
[90] M. Rabinowitz,et al. Analysis of cloned mRNA sequences encoding subfragment 2 and part of subfragment 1 of alpha- and beta-myosin heavy chains of rabbit heart. , 1984, The Journal of biological chemistry.
[91] Michael G. Rosenfeld,et al. Dramatic growth of mice that develop from eggs microinjected with metallothionein–growth hormone fusion genes , 1982, Nature.
[92] F. Doyle,et al. The Acromegaly Syndrome , 1982 .
[93] Y. Watanabe. Serial inbreeding of rabbits with hereditary hyperlipidemia (WHHL-rabbit). , 1980, Atherosclerosis.
[94] G. Brem,et al. Expression of the murine wild-type tyrosinase gene in transgenic rabbits , 2005, Transgenic Research.
[95] Jianglin Fan,et al. Transgenic rabbits expressing human lipoprotein lipase , 2004, Cytotechnology.
[96] H. Niemann,et al. Expression of active human blood clotting factor VIII in mammary gland of transgenic rabbits. , 2003, DNA and cell biology.
[97] L. Montoliu. Gene transfer strategies in animal transgenesis. , 2002, Cloning and stem cells.
[98] Yifan Dai,et al. Targeted disruption of the alpha1,3-galactosyltransferase gene in cloned pigs. , 2002, Nature biotechnology.
[99] H. Yoshida,et al. Production of human monoclonal and polyclonal antibodies in TransChromo animals. , 2002, Cloning and stem cells.
[100] J. Smeitink,et al. Enzyme therapy for pompe disease with recombinant human alpha-glucosidase from rabbit milk. , 2001, Journal of inherited metabolic disease.
[101] J. Charrow,et al. Recombinant human acid α-glucosidase enzyme therapy for infantile glycogen storage disease type II: Results of a phase I/II clinical trial , 2001, Genetics in Medicine.
[102] HuijunSun,et al. Transgenic Rabbits Expressing Human Apolipoprotein(a) Develop More Extensive Atherosclerotic Lesions in Response to a Cholesterol-Rich Diet , 2001 .
[103] Jianglin Fan,et al. Transgenic rabbits expressing human apolipoprotein (a). , 2000, Journal of atherosclerosis and thrombosis.
[104] A. Reuser,et al. Recombinant human alpha-glucosidase from rabbit milk in Pompe patients. , 2000, Lancet.
[105] C. Palmer,et al. Transgenic animal bioreactors--where we are. , 2000, Transgenic research.
[106] G. Brem,et al. Generation and Application of Transgenic Rabbits , 1998 .
[107] E. Wolf,et al. Human Insulin-Like Growth Factor I (IGF-I) Produced in the Mammary Glands of Transgenic Rabbits: Yield, Receptor Binding, Mitogenic Activity, and Effects on IGF-Binding Proteins , 1997 .
[108] L. Houdebine,et al. The deleterious effects of human erythropoietin gene driven by the rabbit whey acidic protein gene promoter in transgenic rabbits. , 1996, Reproduction, nutrition, development.
[109] J. de la Fuente,et al. Expression of active human erythropoietin in the mammary gland of lactating transgenic mice and rabbits. , 1995, Biological research.
[110] J. Kreider,et al. Methylation of cottontail rabbit papillomavirus DNA and tissue-specific expression in transgenic rabbits. , 1995, Virus research.
[111] G. Brem,et al. Mammary gland specific expression of chymosin constructs in transgenic rabbits , 1995 .
[112] P. Wilson,et al. Lipoprotein(a) and coronary heart disease. , 1994, Chemistry and physics of lipids.
[113] J. McCord,et al. Superoxide dismutase: pharmacological developments and applications. , 1992, Advances in pharmacology.
[114] J. McCune,et al. The SCID-hu mouse: a small animal model for HIV infection and pathogenesis. , 1991, Annual review of immunology.
[115] C. Holt,et al. The composition of milk. , 1983 .
[116] 西条 元彦. Lecithin Cholesterol Acyltransferaseに関する研究 : Lecithin Cholesterol Acyltransferaseとリポ蛋白の関係について , 1974 .
[117] A. Keller,et al. Composition of milk. , 1930, Nutrition reviews.
[118] M. Murovska,et al. ANTISENSE RNA-MEDIATED INHIBITION OF BOVINE LEUKEMIA VIRUS REPLICATION IN TRANSGENIC RABBITS , 2022 .