Endoscopic mucosal resection.

We are now finding more malignancies in their early stages than previously. Attempts to ablate these lesions are difficult and do not provide the histological information required to decide on further treatment. Surgery is difficult to justify, as only a minority of lesions are associated with lymph node metastases and lesions may not become clinically relevant within the lifetime of an elderly patient. Endoscopic mucosal resection allows cancers to be resected at minimal cost, morbidity and mortality. It is also the most reliable investigation when assessing lesions which are suspicious for containing early cancer. After endoscopic removal, histological assessment of depth of penetration and a search for invasion into lymphatics or venules allows the risk of microscopic lymph node metastases to be predicted. The risk of developing metastatic disease can then be balanced against the risks of surgery in view of the patient's age and health.

[1]  H. Niwa,et al.  Newly designed soft prelooped cap for endoscopic mucosal resection of gastric lesions. , 2003, Gastrointestinal endoscopy.

[2]  Nib Soehendra,et al.  Endoscopic mucosal resection. , 2001, Gastrointestinal endoscopy.

[3]  H. Mitomi,et al.  Clinical outcome of endoscopic aspiration mucosectomy for early stage gastric cancer. , 2002, Gastrointestinal endoscopy.

[4]  K. Sugano,et al.  Success rate of curative endoscopic mucosal resection with circumferential mucosal incision assisted by submucosal injection of sodium hyaluronate. , 2002, Gastrointestinal endoscopy.

[5]  M. Asaka,et al.  Long-term outcome after endoscopic mucosal resection in patients with esophageal squamous cell carcinoma invading the muscularis mucosae or deeper. , 2002, Gastrointestinal endoscopy.

[6]  L. Gossner,et al.  Intraepithelial high-grade neoplasia and early adenocarcinoma in short-segment Barrett's esophagus (SSBE): curative treatment using local endoscopic treatment techniques. , 2002, Endoscopy.

[7]  Syed G. Shah,et al.  Treatment with argon plasma coagulation reduces recurrence after piecemeal resection of large sessile colonic polyps: a randomized trial and recommendations. , 2002, Gastrointestinal endoscopy.

[8]  E. Furth,et al.  Efficacy, safety, and clinical outcomes of endoscopic mucosal resection: a study of 101 cases. , 2002, Gastrointestinal endoscopy.

[9]  L. Burgart,et al.  Risk of Lymph Node Metastasis in T1 Carcinoma of the Colon and Rectum , 2002, Diseases of the colon and rectum.

[10]  I. Waxman.  Endosonography-assisted endoscopic mucosal resection of submucosal tumors of the gastrointestinal tract , 2002 .

[11]  T. Fujii,et al.  Chromoscopy During Colonoscopy , 2001, Endoscopy.

[12]  Kenneth K Wang,et al.  Combined endoscopic mucosal resection and photodynamic therapy for esophageal neoplasia within Barrett's esophagus. , 2001, Gastrointestinal endoscopy.

[13]  H. Suzuki.  Endoscopic mucosal resection using ligating device for early gastric cancer. , 2001, Gastrointestinal endoscopy clinics of North America.

[14]  S. Kudo,et al.  Endoscopic mucosal resection of the colon: the Japanese technique. , 2001, Gastrointestinal endoscopy clinics of North America.

[15]  S. Endo,et al.  Lifting of lesions during endoscopic mucosal resection (EMR) of early colorectal cancer: implications for the assessment of resectability. , 2001, Endoscopy.

[16]  J. Waye.  Endoscopic mucosal resection of colon polyps. , 2001, Gastrointestinal endoscopy clinics of North America.

[17]  K. Chayama,et al.  Clinicopathologic features and endoscopic treatment of superficially spreading colorectal neoplasms larger than 20 mm. , 2001, Gastrointestinal endoscopy.

[18]  M. Tada.  Endoscopic mucosal resection of the stomach: initial description. , 2001, Gastrointestinal endoscopy clinics of North America.

[19]  H. Makuuchi.  Endoscopic mucosal resection for mucosal cancer in the esophagus. , 2001, Gastrointestinal endoscopy clinics of North America.

[20]  A B West,et al.  Prevalence and distinctive biologic features of flat colorectal adenomas in a North American population. , 2001, Gastroenterology.

[21]  H. Tajiri,et al.  Assessment of colorectal lesions using magnifying colonoscopy and mucosal dye spraying: can significant lesions be distinguished? , 2001, Endoscopy.

[22]  H. Tajiri,et al.  New Endoscopic Treatment for Intramucosal Gastric Tumors Using an Insulated-Tip Diathermic Knife , 2001, Endoscopy.

[23]  H. Nawata,et al.  Preoperative evaluation of submucosal invasive colorectal cancer using a 15-MHz ultrasound miniprobe. , 2001, Endoscopy.

[24]  H. Ono,et al.  Evaluation of the necessity for gastrectomy with lymph node dissection for patients with submucosal invasive gastric cancer , 2001, The British journal of surgery.

[25]  S. Yoshida,et al.  Endoscopic mucosal resection for treatment of early gastric cancer , 2001, Gut.

[26]  H. Inoue.  Treatment of esophageal and gastric tumors. , 2001, Endoscopy.

[27]  C. Lightdale,et al.  Lugol chromoendoscopy for esophageal squamous cell cancer. , 2001, Endoscopy.

[28]  S. Inatsuchi.  BROADENING OF THE INDICATIONS FOR ENDOSCOPIC SURGERY : UPPER GASTROINTESTINAL TRACT , 2000 .

[29]  S. Inatsuchi.  Plenary Lecture: Broadening of the Indications for Endoscopic Surgery: Upper Gastrointestinal Tract , 2000 .

[30]  Y. Nakanishi,et al.  Incidence of lymph node metastasis from early gastric cancer: estimation with a large number of cases at two large centers , 2000, Gastric Cancer.

[31]  N. Oshitani,et al.  Endoscopic Resection of Small Rectal Carcinoid Tumours Using an Aspiration Method with a Transparent Overcap , 2000, The Journal of international medical research.

[32]  Kenneth J. Chang,et al.  Endoscopic mucosal resection. Current concepts. , 2000, Gastrointestinal endoscopy clinics of North America.

[33]  Shin-ei Kudo,et al.  Colonoscopic Diagnosis and Management of Nonpolypoid Early Colorectal Cancer , 2000, World Journal of Surgery.

[34]  H. P. Wang,et al.  Low frequency of bacteremia after endoscopic mucosal resection. , 2000, Gastrointestinal endoscopy.

[35]  M F Dixon,et al.  The Vienna classification of gastrointestinal epithelial neoplasia , 2000, Gut.

[36]  K. Haruma,et al.  Conditions of curability after endoscopic resection for colorectal carcinoma with submucosally massive invasion. , 2000, Oncology reports.

[37]  T. Fujii,et al.  Flat and depressed colonic neoplasms: a prospective study of 1000 colonoscopies in the UK , 2000, The Lancet.

[38]  L. Gossner,et al.  Endoscopic mucosal resection of early cancer and high-grade dysplasia in Barrett's esophagus. , 2000, Gastroenterology.

[39]  R. Fujita,et al.  Hemoclipping for postpolypectomy and postbiopsy colonic bleeding. , 2000, Gastrointestinal endoscopy.

[40]  A. Burroughs,et al.  Evidence-Based Gastroenterology and Hepatology , 1999 .

[41]  H. Mitomi,et al.  Usefulness of endoscopic aspiration mucosectomy as compared with strip biopsy for the treatment of gastric mucosal cancer. , 1999, Gastrointestinal endoscopy.

[42]  R. Fujita,et al.  Diagnosis of submucosal tumor of the upper GI tract by endoscopic resection. , 1999, Gastrointestinal endoscopy.

[43]  O. Chino,et al.  Endoscopic mucosal resection for early gastric cancer. , 1999, Seminars in surgical oncology.

[44]  A. Munakata,et al.  Correlation of lifting versus non-lifting and microscopic depth of invasion in early colorectal cancer. , 1999, Gastrointestinal endoscopy.

[45]  J H Peters,et al.  Occult esophageal adenocarcinoma: extent of disease and implications for effective therapy. , 1999, Annals of surgery.

[46]  Yukihiro Sato,et al.  A novel method of endoscopic mucosal resection using sodium hyaluronate. , 1999, Gastrointestinal endoscopy.

[47]  C. Shim,et al.  Staining in Gastrointestinal Endoscopy: Clinical Application and Limitations , 1999, Endoscopy.

[48]  H. Chun,et al.  Endoscopic removal of submucous tumours. , 1999, Bailliere's best practice & research. Clinical gastroenterology.

[49]  N. Kinukawa,et al.  An early gastric carcinoma treatment strategy based on analysis of lymph node metastasis , 1999, Cancer.

[50]  S. Tsujitani,et al.  Less invasive surgery for early gastric cancer based on the low probability of lymph node metastasis. , 1999, Surgery.

[51]  A. Terano,et al.  Treatment of gastric tumors by endoscopic mucosal resection with a ligating device. , 1999, Gastrointestinal endoscopy.

[52]  H. Nawata,et al.  Pretreatment staging of endoscopically early gastric cancer with a 15 MHz ultrasound catheter probe. , 1998, Gastrointestinal endoscopy.

[53]  T. Kojima,et al.  Outcome of endoscopic mucosal resection for early gastric cancer: review of the Japanese literature. , 1998, Gastrointestinal endoscopy.

[54]  J. Watari,et al.  Invasion depth diagnosis of depressed type early colorectal cancers by combined use of videoendoscopy and chromoendoscopy. , 1998, Gastrointestinal endoscopy.

[55]  J F Mayberry,et al.  Flat adenomas exist in asymptomatic people: important implications for colorectal cancer screening programmes , 1998, Gut.

[56]  Y. Murata,et al.  Endoscopic Ultrasonography in Diagnosis and Mucosal Resection for Early Esophageal Cancer , 1998, Endoscopy.

[57]  M. Watanabe,et al.  Staging of Gastric Cancer with Endoscopic Ultrasonography and Endoscopic Mucosal Resection , 1998, Endoscopy.

[58]  P R Taylor,et al.  Mucosal iodine staining improves endoscopic visualization of squamous dysplasia and squamous cell carcinoma of the esophagus in linxian, china , 1998, Cancer.

[59]  H. Inoue.  Endoscopic mucosal resection for esophageal and gastric mucosal cancers. , 1998, Canadian journal of gastroenterology = Journal canadien de gastroenterologie.

[60]  I. Shimokawa,et al.  Esophageal granular cell tumor treated by endoscopic mucosal resection using a ligating device. , 1998, Gastrointestinal endoscopy.

[61]  H. Goto,et al.  Endoscopic resection of small duodenal carcinoid tumors with strip biopsy technique. , 1998, Gastrointestinal endoscopy.

[62]  T. Kakegawa,et al.  Treatment of superficial cancer of the esophagus: a summary of responses to a questionnaire on superficial cancer of the esophagus in Japan. , 1998, Surgery.

[63]  M. Stolte,et al.  Differences in the diagnostic criteria used by japanese and western pathologists to diagnose colorectal carcinoma , 1998, Cancer.

[64]  T R DeMeester,et al.  Surgical treatment of dysplasia and adenocarcinoma. , 1997, Gastroenterology clinics of North America.

[65]  T. Zarchy.  Risk of submucosal saline injection for colonic polypectomy. , 1997, Gastrointestinal endoscopy.

[66]  M. Stolte,et al.  Differences in diagnostic criteria for gastric carcinoma between Japanese and Western pathologists , 1997, The Lancet.

[67]  N. Soehendra,et al.  Endoscopic Snare Mucosectomy in the Esophagus without Any Additional Equipment: A Simple Technique for Resection of Flat Early Cancer , 1997, Endoscopy.

[68]  M. Okuma,et al.  Endoscopic resection of rectal carcinoid tumors using aspiration lumpectomy. , 1997, Endoscopy.

[69]  R. Yoshinaka,et al.  Endoscopic ultrasound-assisted band ligation: a new technique for resection of submucosal tumors. , 1996, Gastrointestinal endoscopy.

[70]  C. Shim.  Endoscopic mucosal resection. , 1996, Journal of Korean medical science.

[71]  H. Inoue,et al.  Colonic mucosal resection using a transparent cap-fitted endoscope. , 1996, Gastrointestinal endoscopy.

[72]  M. Itoh,et al.  Injection-incision--assisted snare resection of large sessile colorectal polyps. , 1996, Gastrointestinal endoscopy.

[73]  N. Soehendra,et al.  Endoscopic snare excision of "giant" colorectal polyps. , 1996, Gastrointestinal endoscopy.

[74]  S. Takeo,et al.  Clinicopathological features of lymph node metastasis in early gastric cancer. , 1995, International surgery.

[75]  G. Ballantyne,et al.  Carcinoids of the rectum. , 1994, Journal of the American College of Surgeons.

[76]  A. Munakata,et al.  The non-lifting sign of invasive colon cancer. , 1994, Gastrointestinal endoscopy.

[77]  A. Yanagisawa,et al.  Endoscopic Resection of Early Gastric Carcinoma: Results of a Retrospective Analysis of 308 Cases , 1994, Endoscopy.

[78]  Tsuneya Nakamura,et al.  Safer colonoscopic polypectomy with local submucosal injection of hypertonic saline-epinephrine solution. , 1994, The American journal of gastroenterology.

[79]  S. Kudo,et al.  Endoscopic Mucosal Resection of Flat and Depressed Types of Early Colorectal Cancer , 1993, Endoscopy.

[80]  K. Okita,et al.  Endoscopic Resection of Early Gastric Cancer , 1993, Endoscopy.

[81]  H. Inoue,et al.  Endoscopic mucosal resection with a cap-fitted panendoscope for esophagus, stomach, and colon mucosal lesions. , 1993, Gastrointestinal endoscopy.

[82]  K. Okita,et al.  The successive strip biopsy partial resection technique for large early gastric and colon cancers. , 1992, Gastrointestinal endoscopy.

[83]  T. Kawano,et al.  A New Technique for Endoscopic Esophageal Mucosectomy Using a Transparent Overtube with Intraluminal Negative Pressure (np‐EEM) , 1991 .

[84]  K. Okita,et al.  Endoscopic therapy for early colon cancer: the strip biopsy resection technique. , 1991, Gastrointestinal endoscopy.

[85]  K Masuda,et al.  Endoscopic resection of early gastric cancer and other tumors with local injection of hypertonic saline-epinephrine. , 1988, Gastrointestinal endoscopy.