Three-dimensional dynamic functional mapping of cardiac mechanics

The heart is an organ which functions by a periodic change of the three dimensional (3D) spatially distributed parameters; malfunctions of the heart's operating systems are manifested by changes of the spatio-temporal heart shape dynamics. This paper attempts to present a set of image analysis tools aimed at a thorough study of the left ventricular (LV) shape-function relationship based on Cine-CT data. Data processing methodologies aimed at analysis and interpretation of the dynamic 3D LV shape, thickening and motion are described. These include the computerized detection of the LV boundaries, dynamic reconstruction of 3D LV shape, the LV shape parameters and their spatio-temporal evolution. The procedures are demonstrated using Cine-CT images of the human LV is normal and pathological cases.

[1]  A. Amini,et al.  Detection And Tracking Of The IV Endocardial Surface From 3D Image Sequences , 1991, Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society Volume 13: 1991.

[2]  G. Mailloux,et al.  Computer Analysis of Heart Motion from Two-Dimensional Echocardiograms , 1987, IEEE Transactions on Biomedical Engineering.

[3]  W. F. Ames,et al.  Phase retrieval and zero crossings (Mathematical methods in image reconstruction) , 1990 .

[4]  M. Marcus,et al.  Ultrafast computed tomography in the diagnosis of cardiac disease. , 1989, The American journal of cardiology.

[5]  S Sideman,et al.  Quantitative characterization and sorting of three-dimensional geometries: application to left ventricles in vivo. , 1989, IEEE transactions on bio-medical engineering.

[6]  S Sideman,et al.  Three-dimensional mapping of acute ischemic regions using MRI: wall thickening versus motion analysis. , 1990, The American journal of physiology.

[7]  Samuel Sideman,et al.  Regional Three‐Dimensional Geometry and Function of Left Ventricles With Fibrous Aneurysms: A Cine‐Computed Tomography Study , 1991, Circulation.

[8]  D. Kass,et al.  Mechanism of Global Functional Recovery Despite Sustained Postischemic Regional Stunning , 1992, Circulation.

[9]  D. Adam,et al.  Automatic ventricular cavity boundary detection from sequential ultrasound images using simulated annealing. , 1989, IEEE transactions on medical imaging.

[10]  R Beyar,et al.  Quantification and validation of left ventricular wall thickening by a three-dimensional volume element magnetic resonance imaging approach. , 1990, Circulation.

[11]  Samuel Sideman,et al.  IMAGING AND ANALYSIS OF DYNAMIC FIELDS , 1992 .

[12]  Eric A. Hoffman,et al.  A historical perspective of heart and lung 3D imaging , 1991 .