Nucleoside-modified mRNA immunization elicits influenza virus hemagglutinin stalk-specific antibodies
暂无分享,去创建一个
D. Weissman | Seth J. Zost | S. Hensley | F. Krammer | M. Hope | Ying K. Tam | T. D. Madden | B. Mui | K. Karikó | M. McMahon | Ericka Kirkpatrick | N. Pardi | Chris Barbosa | Kaela Parkhouse
[1] J. Mascola,et al. Is It Possible to Develop a "Universal" Influenza Virus Vaccine? Immunogenetic Considerations Underlying B-Cell Biology in the Development of a Pan-Subtype Influenza A Vaccine Targeting the Hemagglutinin Stem. , 2018, Cold Spring Harbor perspectives in biology.
[2] A. García-Sastre,et al. Is It Possible to Develop a "Universal" Influenza Virus Vaccine? Potential Target Antigens and Critical Aspects for a Universal Influenza Vaccine. , 2018, Cold Spring Harbor perspectives in biology.
[3] F. Scorza,et al. New Kids on the Block: RNA-Based Influenza Virus Vaccines , 2018, Vaccines.
[4] D. Weissman,et al. mRNA vaccines — a new era in vaccinology , 2018, Nature Reviews Drug Discovery.
[5] Seth J. Zost,et al. Contemporary H3N2 influenza viruses have a glycosylation site that alters binding of antibodies elicited by egg-adapted vaccine strains , 2017, Proceedings of the National Academy of Sciences.
[6] M. Fotin‐Mleczek,et al. Unmodified mRNA in LNPs constitutes a competitive technology for prophylactic vaccines , 2017, npj Vaccines.
[7] I. Wilson,et al. A structural explanation for the low effectiveness of the seasonal influenza H3N2 vaccine , 2017, PLoS pathogens.
[8] R. Albrecht,et al. A universal influenza virus vaccine candidate confers protection against pandemic H1N1 infection in preclinical ferret studies , 2017, npj Vaccines.
[9] Kimberly J. Hassett,et al. Preclinical and Clinical Demonstration of Immunogenicity by mRNA Vaccines against H10N8 and H7N9 Influenza Viruses , 2017, Molecular therapy : the journal of the American Society of Gene Therapy.
[10] D. Christensen,et al. Robust antibody and CD8+ T-cell responses induced by P. falciparum CSP adsorbed to cationic liposomal adjuvant CAF09 confer sterilizing immunity against experimental rodent malaria infection , 2017, npj Vaccines.
[11] R. Hai,et al. Chimeric Hemagglutinin Constructs Induce Broad Protection against Influenza B Virus Challenge in the Mouse Model , 2017, Journal of Virology.
[12] D. Weissman,et al. Zika virus protection by a single low dose nucleoside modified mRNA vaccination , 2017, Nature.
[13] Nicole M. Bouvier,et al. Defining the antibody cross-reactome against the influenza virus surface glycoproteins , 2017, Nature Immunology.
[14] Caitlin E. Mullarkey,et al. Optimal activation of Fc-mediated effector functions by influenza virus hemagglutinin antibodies requires two points of contact , 2016, Proceedings of the National Academy of Sciences.
[15] S. Bertholet,et al. Self-Amplifying mRNA Vaccines Expressing Multiple Conserved Influenza Antigens Confer Protection against Homologous and Heterosubtypic Viral Challenge , 2016, PloS one.
[16] Daniel G. Anderson,et al. Dendrimer-RNA nanoparticles generate protective immunity against lethal Ebola, H1N1 influenza, and Toxoplasma gondii challenges with a single dose , 2016, Proceedings of the National Academy of Sciences.
[17] Caitlin E. Mullarkey,et al. Both Neutralizing and Non-Neutralizing Human H7N9 Influenza Vaccine-Induced Monoclonal Antibodies Confer Protection. , 2016, Cell host & microbe.
[18] F. Krammer. Novel universal influenza virus vaccine approaches. , 2016, Current opinion in virology.
[19] R. Varadarajan,et al. Stalking influenza by vaccination with pre-fusion headless HA mini-stem , 2016, Scientific Reports.
[20] D. Weissman,et al. Expression kinetics of nucleoside-modified mRNA delivered in lipid nanoparticles to mice by various routes. , 2015, Journal of controlled release : official journal of the Controlled Release Society.
[21] P. Mason,et al. Induction of Broad-Based Immunity and Protective Efficacy by Self-amplifying mRNA Vaccines Encoding Influenza Virus Hemagglutinin , 2015, Journal of Virology.
[22] Adrian Apetri,et al. A stable trimeric influenza hemagglutinin stem as a broadly protective immunogen , 2015, Science.
[23] J. Mascola,et al. Hemagglutinin-stem nanoparticles generate heterosubtypic influenza protection , 2015, Nature Medicine.
[24] T. Schlake,et al. Sequence-engineered mRNA Without Chemical Nucleoside Modifications Enables an Effective Protein Therapy in Large Animals , 2015, Molecular therapy : the journal of the American Society of Gene Therapy.
[25] Steven F. Baker,et al. High-Affinity H7 Head and Stalk Domain-Specific Antibody Responses to an Inactivated Influenza H7N7 Vaccine After Priming With Live Attenuated Influenza Vaccine. , 2015, The Journal of infectious diseases.
[26] P. Palese,et al. Advances in the development of influenza virus vaccines , 2015, Nature Reviews Drug Discovery.
[27] K. Subbarao,et al. Live attenuated H7N7 influenza vaccine primes for a vigorous antibody response to inactivated H7N7 influenza vaccine. , 2014, Vaccine.
[28] R. Karron,et al. A live attenuated influenza A(H5N1) vaccine induces long-term immunity in the absence of a primary antibody response. , 2014, The Journal of infectious diseases.
[29] P. Palese,et al. Broadly neutralizing hemagglutinin stalk–specific antibodies require FcγR interactions for protection against influenza virus in vivo , 2014, Nature Medicine.
[30] P. Palese,et al. Expression of functional recombinant hemagglutinin and neuraminidase proteins from the novel H7N9 influenza virus using the baculovirus expression system. , 2013, Journal of visualized experiments : JoVE.
[31] Florian Krammer,et al. Influenza virus hemagglutinin stalk-based antibodies and vaccines. , 2013, Current opinion in virology.
[32] K. G. Rajeev,et al. Biodegradable lipids enabling rapidly eliminated lipid nanoparticles for systemic delivery of RNAi therapeutics. , 2013, Molecular therapy : the journal of the American Society of Gene Therapy.
[33] J. Plotkin,et al. Immune history shapes specificity of pandemic H1N1 influenza antibody responses , 2013, The Journal of experimental medicine.
[34] R. Hai,et al. Chimeric Hemagglutinin Influenza Virus Vaccine Constructs Elicit Broadly Protective Stalk-Specific Antibodies , 2013, Journal of Virology.
[35] T. Schlake,et al. Protective efficacy of in vitro synthesized, specific mRNA vaccines against influenza A virus infection , 2012, Nature Biotechnology.
[36] Jens C. Krause,et al. A Carboxy-Terminal Trimerization Domain Stabilizes Conformational Epitopes on the Stalk Domain of Soluble Recombinant Hemagglutinin Substrates , 2012, PloS one.
[37] Shigeo Matsuda,et al. Maximizing the Potency of siRNA Lipid Nanoparticles for Hepatic Gene Silencing In Vivo** , 2012, Angewandte Chemie.
[38] R. Albrecht,et al. Influenza Viruses Expressing Chimeric Hemagglutinins: Globular Head and Stalk Domains Derived from Different Subtypes , 2012, Journal of Virology.
[39] Adolfo García-Sastre,et al. Hemagglutinin stalk antibodies elicited by the 2009 pandemic influenza virus as a mechanism for the extinction of seasonal H1N1 viruses , 2012, Proceedings of the National Academy of Sciences.
[40] F. Ennis,et al. Complement-Dependent Lysis of Influenza A Virus-Infected Cells by Broadly Cross-Reactive Human Monoclonal Antibodies , 2011, Journal of Virology.
[41] D. Weissman,et al. Generating the optimal mRNA for therapy: HPLC purification eliminates immune activation and improves translation of nucleoside-modified, protein-encoding mRNA , 2011, Nucleic acids research.
[42] W. C. Hwang,et al. Wide Prevalence of Heterosubtypic Broadly Neutralizing Human Anti–Influenza A Antibodies , 2011, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.
[43] G. Nabel,et al. Induction of Broadly Neutralizing H1N1 Influenza Antibodies by Vaccination , 2010, Science.
[44] K. Subbarao,et al. Heterosubtypic neutralizing antibodies are produced by individuals immunized with a seasonal influenza vaccine. , 2010, The Journal of clinical investigation.
[45] James E. Crowe,et al. Structural Basis of Preexisting Immunity to the 2009 H1N1 Pandemic Influenza Virus , 2010, Science.
[46] Hiroki Kato,et al. Incorporation of pseudouridine into mRNA yields superior nonimmunogenic vector with increased translational capacity and biological stability. , 2008, Molecular therapy : the journal of the American Society of Gene Therapy.
[47] Stephen C. Jones,et al. CD4+ T‐cell memory: generation and multi‐faceted roles for CD4+ T cells in protective immunity to influenza , 2006, Immunological reviews.
[48] D. Weissman,et al. Nucleoside Modified mRNA Vaccines for Infectious Diseases. , 2017, Methods in molecular biology.
[49] A. García-Sastre,et al. Is It Possible to Develop a “Universal” Influenza Virus Vaccine? Toward a Universal Influenza Virus Vaccine: Potential Target Antigens and Critical Aspects for Vaccine Development , 2017 .
[50] D. Weissman,et al. HPLC purification of in vitro transcribed long RNA. , 2013, Methods in molecular biology.
[51] D. Weissman,et al. In vitro transcription of long RNA containing modified nucleosides. , 2013, Methods in molecular biology.