Studies on the Mechanisms of Shear-Induced Platelet Activation

The importance of flow-related phenomena in thrombotic and thrombembolic events has been appreciated by a number of workers for several years. In the last decade, a series of studies have focused specifically on the action of shear stress due to fluid motion on human blood platelets. The shear field may modify the platelet directly, in addition to the role of increasing platelet motion, collision, and contact with solid surfaces. Also, it is clear that both the rates and the extent of response of platelets to various agonists depend heavily on the shear field. A review is available [24], as well as several recent papers [5–7, 21, 25, 35, 37, 44–47].

[1]  J D Hellums,et al.  The kinetics of platelet aggregation induced by fluid-shearing stress. , 1984, Microvascular research.

[2]  H Schmid-Schönbein,et al.  Platelet and Coagulation Parameters Following Millisecond Exposure to Laminar Shear Stress , 1985, Thrombosis and Haemostasis.

[3]  N. Aoki,et al.  Preparation of thrombomodulin from human placenta. , 1985, Thrombosis research.

[4]  J. Joist,et al.  Factors influencing shear-induced platelet alterations: platelet lysis is independent of platelet aggregation and release. , 1981, Thrombosis research.

[5]  G. Born.  Fluid-mechanical and biochemical interactions in haemostasis. , 1977, British medical bulletin.

[6]  M. Frojmovic,et al.  Platelet aggregation in laminar flow. I. Adenosine diphosphate concentration, time and shear rate dependence. , 1982, Thrombosis research.

[7]  J D Hellums,et al.  Platelet lysis and aggregation in shear fields. , 1978, Blood cells.

[8]  M. Jaffrin,et al.  Factors governing hemofiltration (HF) in a parallel plate exchanger with highly permeable membranes. , 1978, Transactions - American Society for Artificial Internal Organs.

[9]  J. Joist,et al.  Role of cytoplasmic and releasable ADP in platelet aggregation induced by laminar shear stress. , 1983, The Journal of laboratory and clinical medicine.

[10]  Turitto Vt,et al.  Blood viscosity, mass transport, and thrombogenesis. , 1982 .

[11]  R. Donnelly,et al.  Platelet survival in patients with homograft and prosthetic heart valves , 1974, Thorax.

[12]  H Schmid-Schönbein,et al.  "Shear induced platelet activation"--a critical reappraisal. , 1985, Biorheology.

[13]  G. Born,et al.  Haemodynamic and biochemical interactions in intravascular platelet aggregation. , 1980, Ciba Foundation symposium.

[14]  E. Berstein,et al.  Effects of surface injury and shear stress on platelet aggregation and serotonin release. , 1975, Transactions - American Society for Artificial Internal Organs.

[15]  M. Weinstein,et al.  Abnormal VIII: von Willebrand factor patterns in the plasma of patients with the hemolytic-uremic syndrome , 1984 .

[16]  McIntire Lv,et al.  Characteristics of shear-induced aggregation in whole blood. , 1984 .

[17]  J. George,et al.  Molecular defects in interactions of platelets with the vessel wall. , 1984, The New England journal of medicine.

[18]  Z. Ruggeri,et al.  Von Willebrand's disease. , 1976, British medical journal.

[19]  B. Coller,et al.  Studies with a murine monoclonal antibody that abolishes ristocetin- induced binding of von Willebrand factor to platelets: additional evidence in support of GPIb as a platelet receptor for von Willebrand factor , 1983 .

[20]  D. Deykin,et al.  Unusually large plasma factor VIII:von Willebrand factor multimers in chronic relapsing thrombotic thrombocytopenic purpura. , 1982, The New England journal of medicine.

[21]  J. Moake,et al.  Binding of radioiodinated human von Willebrand factor to Bernard-Soulier, thrombasthenic and von Willebrand's disease platelets. , 1980, Thrombosis research.

[22]  H. Gritsman,et al.  The biochemical mechanisms of shear-induced platelet aggregation. , 1983, Transactions - American Society for Artificial Internal Organs.

[23]  B. Coller,et al.  A murine monoclonal antibody that completely blocks the binding of fibrinogen to platelets produces a thrombasthenic-like state in normal platelets and binds to glycoproteins IIb and/or IIIa. , 1983, The Journal of clinical investigation.

[24]  E J Roschke,et al.  Fluid shear stress in prosthetic heart valves. , 1977, Journal of biomechanics.

[25]  J. Joist,et al.  Potentiation by red blood cells of shear-induced platelet aggregation: relative importance of chemical and physical mechanisms , 1984 .

[26]  J. Moake,et al.  Platelet response to shear stress: changes in serotonin uptake, serotonin release, and ADP induced aggregation. , 1978, Thrombosis research.

[27]  J. Moake,et al.  Effects of antiplatelet agents on platelets exposed to shear stress. , 1980, Transactions - American Society for Artificial Internal Organs.

[28]  S Chien,et al.  In vivo measurements of "apparent viscosity" and microvessel hematocrit in the mesentery of the cat. , 1980, Microvascular research.

[29]  D W Crawford,et al.  Analysis of pulsatile, viscous blood flow through diseased coronary arteries of man. , 1977, Journal of biomechanics.

[30]  G. Born.  Hemorheological influences on platelet thrombogenesis. , 1983, European Neurology.

[31]  J D Hellums,et al.  Red blood cell damage by shear stress. , 1972, Biophysical journal.

[32]  J. Moake,et al.  THE RESPONSE OF HUMAN PLATELETS TO SHEAR STRESS AT SHORT EXPOSURE TIMES , 1977, Transactions - American Society for Artificial Internal Organs.

[33]  C. Guimont,et al.  Experimental investigation of the rheological activation of blood platelets. , 1985, Biorheology.

[34]  J D Hellums,et al.  Morphological, biochemical, and functional changes in human platelets subjected to shear stress. , 1975, The Journal of laboratory and clinical medicine.

[35]  H. Weiss,et al.  Platelet interaction with rabbit subendothelium in von Willebrand's disease: altered thrombus formation distinct from defective platelet adhesion. , 1984, The Journal of clinical investigation.

[36]  Todd D. Giorgio,et al.  Shear-induced platelet aggregation requires von Willebrand factor and platelet membrane glycoproteins Ib and IIb-IIIa. , 1987 .

[37]  S. Russell,et al.  Interaction of asialo von Willebrand factor with glycoprotein Ib induces fibrinogen binding to the glycoprotein IIb/IIIa complex and mediates platelet aggregation. , 1985, The Journal of clinical investigation.

[38]  J. D. Hellums,et al.  A note on the use of Quin2 in studying shear-induced platelet aggregation. , 1986, Thrombosis research.

[39]  P. Richardson.  Rheological factors in platelet - vessel wall interactions. , 1981, Philosophical transactions of the Royal Society of London. Series B, Biological sciences.

[40]  P. Görög,et al.  Aggregation of platelets in damaged vessels. , 1981, Philosophical transactions of the Royal Society of London. Series B, Biological sciences.

[41]  B. Coller,et al.  Asialo von Willebrand factor interactions with platelets. Interdependence of glycoproteins Ib and IIb/IIIa for binding and aggregation. , 1985, The Journal of clinical investigation.

[42]  J. Moake,et al.  The effect of PGI2 and theophylline on the response of platelets subjected to shear stress , 1981 .