Food intake increases liver stiffness in patients with chronic or resolved hepatitis C virus infection

Background and aims:  Transient elastography is increasingly being used in patients with chronic liver disease. It has proven particularly useful to identify patients with advanced fibrosis or cirrhosis, while classification of no or little fibrosis appears to be difficult. In general, stiffness values <6 kPa are considered normal, whereas patients with higher levels are candidates for a disease‐specific treatment or further diagnostic evaluation. Parameters influencing liver stiffness may include food intake that increases liver blood flow.

[1]  M. Friedrich-Rust,et al.  Reproducibility and limitations of transient elastography , 2009, Liver international : official journal of the International Association for the Study of the Liver.

[2]  T. Berg,et al.  Expert opinion on the treatment of patients with chronic hepatitis C , 2009, Journal of viral hepatitis.

[3]  Edward A Belongia,et al.  National Institutes of Health Consensus Development Conference Statement: management of hepatitis B. , 2009, Annals of internal medicine.

[4]  Ioan Sporea,et al.  Comparison of the liver stiffness measurement by transient elastography with the liver biopsy. , 2008, World journal of gastroenterology.

[5]  Gunda Millonig,et al.  Extrahepatic cholestasis increases liver stiffness (FibroScan) irrespective of fibrosis , 2008, Hepatology.

[6]  F. Oberti,et al.  Reproducibility of liver stiffness measurement by ultrasonographic elastometry. , 2008, Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association.

[7]  F. Oberti,et al.  Learning curve and interobserver reproducibility evaluation of liver stiffness measurement by transient elastography: , 2017 .

[8]  Ze-Zhou Song Acute viral hepatitis increases liver stiffness values measured by transient elastography , 2008, Hepatology.

[9]  S. Milani,et al.  Reliability of transient elastography for the diagnosis of advanced fibrosis in chronic hepatitis C , 2008, Gut.

[10]  Anne-Claire Vergnaud,et al.  Liver stiffness values in apparently healthy subjects: influence of gender and metabolic syndrome. , 2008, Journal of hepatology.

[11]  Eva Herrmann,et al.  Performance of transient elastography for the staging of liver fibrosis: a meta-analysis. , 2008, Gastroenterology.

[12]  Dieter Häussinger,et al.  Transient elastography is unreliable for detection of cirrhosis in patients with acute liver damage , 2007, Hepatology.

[13]  Dario Conte,et al.  Reproducibility of transient elastography in the evaluation of liver fibrosis in patients with chronic liver disease , 2007, Gut.

[14]  R. Sacco,et al.  Transient elastography: a new surrogate marker of liver fibrosis influenced by major changes of transaminases , 2007, Journal of viral hepatitis.

[15]  V. de Lédinghen,et al.  Diagnosis of cirrhosis by transient elastography (FibroScan): a prospective study , 2005, Gut.

[16]  M. Pirisi,et al.  Value of two noninvasive methods to detect progression of fibrosis among HCV carriers with normal aminotransferases , 2005, Hepatology.

[17]  V. de Lédinghen,et al.  Prospective comparison of transient elastography, Fibrotest, APRI, and liver biopsy for the assessment of fibrosis in chronic hepatitis C. , 2005, Gastroenterology.

[18]  Christos Christidis,et al.  Noninvasive assessment of liver fibrosis by measurement of stiffness in patients with chronic hepatitis C , 2005, Hepatology.

[19]  M. Lafortune,et al.  Meal induced changes in hepatic and splanchnic circulation: a noninvasive Doppler study in normal humans , 2004, European Journal of Applied Physiology and Occupational Physiology.

[20]  V. Paradis,et al.  Sampling variability of liver fibrosis in chronic hepatitis C , 2003, Hepatology.

[21]  M. Ziol,et al.  Transient elastography: a new noninvasive method for assessment of hepatic fibrosis. , 2003, Ultrasound in medicine & biology.

[22]  J. Hoofnagle,et al.  National Institutes of Health Consensus Development Conference: Management of Hepatitis C: 2002 , 2002, Hepatology.

[23]  C. Szinnai, C. Mottet, J.-P. Gutzwiller, J. Drewe, Role of Gender upon Basal and Postprandial Systemic and Splanchnic Haemodynamics in Humans , 2001 .

[24]  M. Manns,et al.  Regulation of hepatic blood flow in patients with liver cirrhosis and after liver transplantation , 2000 .

[25]  E. Stange,et al.  The postprandial portal flow is related to the severity of portal hypertension and liver cirrhosis. , 1998, Journal of hepatology.

[26]  A. Toyonaga,et al.  Postprandial splanchnic hemodynamic response in patients with cirrhosis of the liver: evaluation with "triple-vessel" duplex US. , 1996, Radiology.