This report provides guidelines for ramp and interchange spacing based on design, operations, safety, and signing considerations. The guidelines will be valuable to transportation agencies who need to balance system efficiency and safety with the need to provide access for local users. The guidelines are intended to aid the decision-making process when an agency is considering new ramps or interchanges on existing facilities, modifying ramps and interchanges of existing facilities, or when planning and designing new highway and interchange facilities. The guidelines also offer standardized definitions measuring ramp and interchange spacing, which have varied in previous design manuals guides.