The Amino Acid Sequence of Purothionin A, A Lethal Toxic Protein for Brewer’s Yeasts from Wheat

A protein isolated from wheat flour (Triti cum vulgare, Manitoba No. 3) has been known to have a lethal effect on brewer's yeasts.'-" An extensive purification and characterizations of this protein has recently revealed that it has two components, A and B, and a close similari ty with purothionin4) in its chemical and biological nature. Therefore, we now call our protein "purothionin." In this paper, the primary structure of puro thionin A is described. Purothionin A was