Germline ATG2B/GSKIP-containing 14q32 duplication predisposes to early clonal hematopoiesis leading to myeloid neoplasms
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F. Pasquier | J. Bourhis | C. Deswarte | W. Vainchenker | P. Cony-Makhoul | C. Bellanné-Chantelot | F. Delhommeau | O. Caron | O. Béra | C. Colas | I. Plo | C. Marzac | J. Micol | P. Hirsch | A. Najman | P. Benusiglio | S. Lapusan | P. Pellet | E. Brissot | Hélène Guermouche | G. Leroy | F. Isnard | Graciela Rabadan Moraes | F. S. de Fontbrune | B. Schmaltz-Panneau | Jean Pegliasco | Samy Chraibi | J. Meniane | P. Fuseau | Christine Delaunay-Darivon | Céline Lemaitre
[1] P. Nguyen,et al. Myelodysplastic syndromes , 2009, Nature Reviews Disease Primers.
[2] Ivana V. Yang,et al. Author Correction: Inherited causes of clonal haematopoiesis in 97,691 whole genomes , 2021, Nature.
[3] F. Pasquier,et al. ATG2B/GSKIP in de novo acute myeloid leukemia (AML): high prevalence of germline predisposition in French West Indies , 2021, Leukemia & lymphoma.
[4] V. Ugo,et al. Leukemic evolution of polycythemia vera and essential thrombocythemia: genomic profiles predict time to transformation. , 2020, Blood advances.
[5] Ivana V. Yang,et al. Inherited Causes of Clonal Hematopoiesis in 97,691 TOPMed Whole Genomes , 2020, Nature.
[6] C. Deswarte,et al. High prevalence of clonal hematopoiesis in the blood and bone marrow of healthy volunteers. , 2020, Blood advances.
[7] M. Goodell,et al. Clonal Hematopoiesis: Mechanisms Driving Dominance of Stem Cell Clones. , 2020, Blood.
[8] M. Daly,et al. Inherited myeloproliferative neoplasm risk impacts hematopoietic stem cells , 2020, Nature.
[9] A. Rao,et al. DNMT3A and TET2 mutations reshape hematopoiesis in opposing ways , 2020, Nature Genetics.
[10] W. Vainchenker,et al. Germline genetic factors in the pathogenesis of myeloproliferative neoplasms. , 2020, Blood reviews.
[11] C. Bloomfield,et al. Additional gene mutations may refine the 2017 European LeukemiaNet classification in adult patients with de novo acute myeloid leukemia aged <60 years , 2020, Leukemia.
[12] Anna L. Brown,et al. RUNX1-mutated families show phenotype heterogeneity and a somatic mutation profile unique to germline predisposed AML. , 2020, Blood advances.
[13] Rafael C. Schulman,et al. DNA methylation disruption reshapes the hematopoietic differentiation landscape , 2020, Nature Genetics.
[14] G. Challen,et al. Divergent Effects of Dnmt3a and Tet2 Mutations on Hematopoietic Progenitor Cell Fitness , 2020, Stem cell reports.
[15] D. Steinemann,et al. The complex genetic landscape of familial MDS and AML reveals pathogenic germline variants , 2020, Nature Communications.
[16] D. Spencer,et al. Inflammatory Cytokines Promote Clonal Hematopoiesis with Specific Mutations in Ulcerative Colitis Patients. , 2019, Experimental hematology.
[17] J. Soulier,et al. Germline DDX41 mutations define a significant entity within adult MDS/AML patients. , 2019, Blood.
[18] A. Shimamura,et al. Genetic predisposition to MDS: clinical features and clonal evolution. , 2019, Blood.
[19] G. Sandusky,et al. Inhibition of Inflammatory Signaling in Tet2 Mutant Preleukemic Cells Mitigates Stress-Induced Abnormalities and Clonal Hematopoiesis. , 2018, Cell stem cell.
[20] P. Campbell,et al. Classification and Personalized Prognosis in Myeloproliferative Neoplasms , 2018, The New England journal of medicine.
[21] S. Fröhling,et al. MBD4 guards against methylation damage and germ line deficiency predisposes to clonal hematopoiesis and early-onset AML. , 2018, Blood.
[22] R. Houlston,et al. Familial risks of acute myeloid leukemia, myelodysplastic syndromes, and myeloproliferative neoplasms. , 2018, Blood.
[23] T. Olson,et al. Germline duplication of ATG2B and GSKIP genes is not required for the familial myeloid malignancy syndrome associated with the duplication of chromosome 14q32 , 2018, Leukemia.
[24] M. Dubé,et al. Lineage restriction analyses in CHIP indicate myeloid bias for TET2 and multipotent stem cell origin for DNMT3A. , 2018, Blood.
[25] Vu Dinh,et al. Microbial signals drive pre-leukaemic myeloproliferation in a Tet2-deficient host , 2018, Nature.
[26] J. Soulier,et al. A landscape of germ line mutations in a cohort of inherited bone marrow failure patients. , 2018, Blood.
[27] R. Wells,et al. An inflammatory environment containing TNFα favors Tet2-mutant clonal hematopoiesis. , 2017, Experimental hematology.
[28] Anna L. Brown,et al. Duplication on Chromosome 14q Identified in Familial Predisposition to Myeloid Malignancies and Myeloproliferative Neoplasms , 2017 .
[29] J. Churpek. Familial myelodysplastic syndrome/acute myeloid leukemia. , 2017, Best practice & research. Clinical haematology.
[30] M. Dubé,et al. DNMT3A and TET2 dominate clonal hematopoiesis and demonstrate benign phenotypes and different genetic predispositions. , 2017, Blood.
[31] L. Aaltonen,et al. Whole-exome sequencing identifies novel candidate predisposition genes for familial polycythemia vera , 2017, Human Genomics.
[32] Bob Löwenberg,et al. Diagnosis and management of AML in adults: 2017 ELN recommendations from an international expert panel. , 2017, Blood.
[33] P. Guglielmelli,et al. Targeted deep sequencing in polycythemia vera and essential thrombocythemia. , 2016, Blood advances.
[34] Nicholas Eriksson,et al. Germ line variants predispose to both JAK2 V617F clonal hematopoiesis and myeloproliferative neoplasms. , 2016, Blood.
[35] M. Cazzola,et al. LNK mutations in familial myeloproliferative neoplasms. , 2016, Blood.
[36] Nicola D. Roberts,et al. Genomic Classification and Prognosis in Acute Myeloid Leukemia. , 2016, The New England journal of medicine.
[37] Mario Cazzola,et al. The 2016 revision to the World Health Organization classification of myeloid neoplasms and acute leukemia. , 2016, Blood.
[38] P. Guglielmelli,et al. Germline transmission of LNKE208Q variant in a family with myeloproliferative neoplasms , 2016, American journal of hematology.
[39] T. Olson,et al. Genetic predisposition to myelodysplastic syndrome and acute myeloid leukemia in children and young adults , 2016, Leukemia & lymphoma.
[40] G. Superti-Furga,et al. Germline RBBP6 mutations in familial myeloproliferative neoplasms. , 2016, Blood.
[41] J. Gribben,et al. Disease evolution and outcomes in familial AML with germline CEBPA mutations. , 2015, Blood.
[42] F. Pasquier,et al. Germline duplication of ATG2B and GSKIP predisposes to familial myeloid malignancies , 2015, Nature Genetics.
[43] Paola Guglielmelli,et al. Genetic variation at MECOM, TERT, JAK2 and HBS1L-MYB predisposes to myeloproliferative neoplasms , 2015, Nature Communications.
[44] D. Neuberg,et al. Acute myeloid leukemia ontogeny is defined by distinct somatic mutations. , 2015, Blood.
[45] Daniel J Weisdorf,et al. Acute Myeloid Leukemia. , 2015, The New England journal of medicine.
[46] M. McCarthy,et al. Age-related clonal hematopoiesis associated with adverse outcomes. , 2014, The New England journal of medicine.
[47] S. Gabriel,et al. Clonal hematopoiesis and blood-cancer risk inferred from blood DNA sequence. , 2014, The New England journal of medicine.
[48] Joshua F. McMichael,et al. Age-related cancer mutations associated with clonal hematopoietic expansion , 2014, Nature Medicine.
[49] M. Cazzola,et al. Common germline variation at the TERT locus contributes to familial clustering of myeloproliferative neoplasms , 2014, American journal of hematology.
[50] G. Superti-Furga,et al. Somatic mutations of calreticulin in myeloproliferative neoplasms. , 2013, The New England journal of medicine.
[51] J. D. Fitzpatrick,et al. Somatic CALR mutations in myeloproliferative neoplasms with nonmutated JAK2. , 2013, The New England journal of medicine.
[52] M. Cazzola,et al. The role of the JAK2 GGCC haplotype and the TET2 gene in familial myeloproliferative neoplasms , 2011, Haematologica.
[53] A. Tichelli,et al. Clonal analysis of TET2 and JAK2 mutations suggests that TET2 can be a late event in the progression of myeloproliferative neoplasms. , 2010, Blood.
[54] W. Vainchenker,et al. Analysis of the ten-eleven translocation 2 (TET2) gene in familial myeloproliferative neoplasms. , 2009, Blood.
[55] Ashot Harutyunyan,et al. A common JAK2 haplotype confers susceptibility to myeloproliferative neoplasms , 2009, Nature Genetics.
[56] C. Pascutto,et al. Prognostic factors for thrombosis, myelofibrosis, and leukemia in essential thrombocythemia: a study of 605 patients , 2008, Haematologica.
[57] M. Björkholm,et al. Increased risks of polycythemia vera, essential thrombocythemia, and myelofibrosis among 24,577 first-degree relatives of 11,039 patients with myeloproliferative neoplasms in Sweden. , 2008, Blood.
[58] M. Cazzola,et al. Familial chronic myeloproliferative disorders: clinical phenotype and evidence of disease anticipation. , 2007, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[59] C. Bloomfield,et al. Proposals and rationale for revision of the World Health Organization diagnostic criteria for polycythemia vera, essential thrombocythemia, and primary myelofibrosis: recommendations from an ad hoc international expert panel. , 2007, Blood.
[60] G. Thomas,et al. Genetic and clinical implications of the Val617Phe JAK2 mutation in 72 families with myeloproliferative disorders. , 2006, Blood.
[61] D. Stockton,et al. Clonal hematopoiesis in familial polycythemia vera suggests the involvement of multiple mutational events in the early pathogenesis of the disease. , 2003, Blood.
[62] H. Kantarjian,et al. Acute myeloid leukemia , 2018, Methods in Molecular Biology.
[63] A. Brebion,et al. Incidence of hematological malignancies in Martinique, French West Indies, overrepresentation of multiple myeloma and adult T cell leukemia/lymphoma , 2001, Leukemia.