Imaging true 3D endoscopic anatomy by incorporating magnetic tracking with optical coherence tomography: proof-of-principle for airways.

Endoscopic imaging using optical coherence tomography (OCT) has been demonstrated as clinically useful in the assessment of human airways. These airways have a complex 3D structure, bending, tapering and bifurcating. Previously published 3D OCT reconstructions have not accounted for changes in the orientation and trajectory of the endoscopic probe as it moves through the airway during imaging. We propose a novel endoscopic setup incorporating a magnetic tracking system that accounts for these changes, yielding reconstructions that reveal the true 3D nature of the imaged anatomy. We characterize the accuracy of the system, and present the first published magnetic tracker-assisted endoscopic OCT reconstructions using a phantom airway.

[1]  J. Fujimoto,et al.  High resolution imaging of the upper respiratory tract with optical coherence tomography: a feasibility study. , 1998, American journal of respiratory and critical care medicine.

[2]  Suzanne LaScalza,et al.  Effect of metal and sampling rate on accuracy of Flock of Birds electromagnetic tracking system. , 2003, Journal of biomechanics.

[3]  H. Feußner,et al.  Electromagnetic catheter navigation during bronchoscopy: validation of a novel method by conventional fluoroscopy. , 2005, Chest.

[4]  H. Colt,et al.  Two-dimensional and 3-dimensional optical coherence tomographic imaging of the airway, lung, and pleura. , 2005, The Journal of thoracic and cardiovascular surgery.

[5]  Suzanne C. Whiteman,et al.  Optical Coherence Tomography: Real-time Imaging of Bronchial Airways Microstructure and Detection of Inflammatory/Neoplastic Morphologic Changes , 2006, Clinical Cancer Research.

[6]  David D Sampson,et al.  Quantitative upper airway imaging with anatomic optical coherence tomography. , 2006, American journal of respiratory and critical care medicine.

[7]  Andrew D. Wiles,et al.  Accuracy assessment protocols for elektromagnetic tracking systems , 2003, CARS.

[8]  David D Sampson,et al.  Using optical coherence tomography to improve diagnostic and therapeutic bronchoscopy. , 2009, Chest.

[9]  Matthew Brenner,et al.  Evaluation of Tracheal Imaging by Optical Coherence Tomography , 2005, Respiration.

[10]  F. Raab,et al.  Magnetic Position and Orientation Tracking System , 1979, IEEE Transactions on Aerospace and Electronic Systems.

[11]  David D. Sampson,et al.  Anatomical Optical Coherence Tomography for Long-Term, Portable, Quantitative Endoscopy , 2008, IEEE Transactions on Biomedical Engineering.

[12]  Mark Schneider,et al.  Development and testing of a new magnetic-tracking device for image guidance , 2007, SPIE Medical Imaging.

[13]  Stephen Lam,et al.  Airway wall thickness assessed using computed tomography and optical coherence tomography. , 2008, American journal of respiratory and critical care medicine.

[14]  David D Sampson,et al.  Elastic properties of the central airways in obstructive lung diseases measured using anatomical optical coherence tomography. , 2011, American journal of respiratory and critical care medicine.

[15]  David D Sampson,et al.  Feasibility of Applying Real-time Optical Imaging During Bronchoscopic Interventions for Central Airway Obstruction , 2010, Journal of bronchology & interventional pulmonology.

[16]  R A McLaughlin,et al.  Measuring airway dimensions during bronchoscopy using anatomical optical coherence tomography , 2009, European Respiratory Journal.

[17]  D. Sampson,et al.  Evaluation of pharyngeal shape and size using anatomical optical coherence tomography in individuals with and without obstructive sleep apnoea , 2008, Journal of sleep research.

[18]  David D Sampson,et al.  Applying anatomical optical coherence tomography to quantitative 3D imaging of the lower airway. , 2008, Optics express.

[19]  David Sampson,et al.  In vivo size and shape measurement of the human upper airway using endoscopic longrange optical coherence tomography. , 2003, Optics express.

[20]  Holger Timinger,et al.  Motion compensated coronary interventional navigation by means of diaphragm tracking and elastic motion models , 2005, Physics in medicine and biology.

[21]  Holger Timinger,et al.  Modality-integrated magnetic catheter tracking for x-ray vascular interventions. , 2005, Physics in medicine and biology.

[22]  G A Dumas,et al.  Calibration of position and angular data from a magnetic tracking device. , 2000, Journal of biomechanics.

[23]  Robert A. McLaughlin,et al.  Anatomical optical coherence tomography: a safe and effective tool for quantitative long-term monitoring of upper airway size and shape , 2008, SPIE BiOS.