Fighting for and losing or gaining control in life.

In JP Henry's work, fighting for and losing control were important concepts in the interpretation of energy mobilization in psychosocial conditions. Attachment and support were important protective and salutogenic factors. These concepts have been applied in a series of epidemiological and psychophysiological real life studies. Job conditions which force the worker to mobilize energy and concomitantly inhibit anabolism could be identified at least partly by means of the demand-control-support model originally proposed by Karasek. The most adverse conditions at work arise when psychological demands are high and at the same time the decision latitude is low. This combination is associated with changes in the regulation of endocrine parameters as well as with increased morbidity--heart disease, functional gastrointestinal symptoms and musculoskeletal disorders. Examples of studies of physiological correlates of psychosocial processes leading to fight for control are also described from outside work activities.