Pathological and immunological observations on tropical spastic paraparesis in patients from jamaica

The neuropathological examination of the spinal cord of 2 Jamaican patients with classical tropical spastic paraparesis disclosed an intense chronic meningomyelitis with demyelination. In the 1 case in which serum and cerebrospinal fluid were available, antibodies to the human T‐lymphotropic virus type 1 were found.

[1]  S. Izumo,et al.  Chronic progressive myelopathy associated with elevated antibodies to human T‐lymphotropic virus type I and adult T‐cell leukemialike cells , 1987, Annals of neurology.

[2]  Richard T. Johnson,et al.  Myelopathies and retroviral infections , 1987, Annals of neurology.

[3]  M. Setoguchi,et al.  NECROPSY FINDINGS IN HTLV-I ASSOCIATED MYELOPATHY , 1987, The Lancet.

[4]  G. de‐Thé,et al.  HTLV-I AND TROPICAL SPASTIC PARAPARESIS IN AFRICA , 1986, The Lancet.

[5]  W. Blattner,et al.  HTLV-I AND TROPICAL SPASTIC PARAPARESIS , 1986, The Lancet.

[6]  R. Garruto,et al.  TREPONEMATOSES AND TROPICAL SPASTIC PARAPARESIS , 1986, The Lancet.

[7]  I. Mineo,et al.  Increased plasma uric acid after exercise in muscle phosphofructokinase deficiency , 1986, Neurology.

[8]  G. Román The Original Description of Lacunes , 1986, Neurology.

[9]  D. Gajdusek,et al.  HTLV-I AND HTLV-III ANTIBODIES AND TROPICAL SPASTIC PARAPARESIS , 1985, The Lancet.

[10]  M. Feinberg,et al.  Multiple sclerosis and human T-cell lymphotropic retroviruses , 1985, Nature.

[11]  F. Barin,et al.  ANTIBODIES TO HUMAN T-LYMPHOTROPIC VIRUS TYPE-I IN PATIENTS WITH TROPICAL SPASTIC PARAPARESIS , 1985, The Lancet.

[12]  G. Román,et al.  Tropical myeloneuropathies , 1985, Neurology.

[13]  R. Gallo,et al.  Methods in laboratory investigation. Application of the indirect enzyme-linked immunosorbent assay microtest to the detection and surveillance of human t cell leukemia-lymphoma virus. , 1983, Laboratory investigation; a journal of technical methods and pathology.

[14]  Silverman Wa Non-treatment of defective newborn babies. , 1980, Lancet.

[15]  G. Tibbling,et al.  Principles of albumin and IgG analyses in neurological disorders. III. Evaluation of IgG synthesis within the central nervous system in multiple sclerosis. , 1977, Scandinavian journal of clinical and laboratory investigation.

[16]  R. D. Montgomery,et al.  A spastic paraplegic syndrome in South India. , 1969, Journal of the neurological sciences.

[17]  P. E. Rodgers THE CLINICAL FEATURES AND AETIOLOGY OF THE NEUROPATHIC SYNDROME IN JAMAICA. , 1965, The West Indian medical journal.

[18]  R. Montgomery,et al.  CLINICAL AND PATHOLOGICAL OBSERVATIONS ON JAMAICAN NEUROPATHY; A REPORT ON 206 CASES. , 1964, Brain : a journal of neurology.

[19]  Feldman Wh Chemotherapy of Tuberculosis , 1946 .