PDZ domain-binding motif of human T-cell leukemia virus type 1 Tax oncoprotein is essential for the interleukin 2 independent growth induction of a T-cell line

[1]  N. Tanaka,et al.  Aberrant Activation of the Interleukin-2 Autocrine Loop through the Nuclear Factor of Activated T Cells by Nonleukemogenic Human T-Cell Leukemia Virus Type 2 but Not by Leukemogenic Type 1 Virus , 2005, Journal of Virology.

[2]  M. Aboud,et al.  Role of Tax protein in human T-cell leukemia virus type-I leukemogenicity , 2004, Retrovirology.

[3]  R. Coffey,et al.  Human T-cell leukemia virus type 1 Tax oncoprotein induces and interacts with a multi-PDZ domain protein, MAGI-3. , 2004, Virology.

[4]  T. Akiyama,et al.  PDZ domain-binding motif of human T-cell leukemia virus type 1 Tax oncoprotein augments the transforming activity in a rat fibroblast cell line. , 2004, Virology.

[5]  Masao Matsuoka,et al.  Human T-cell leukemia virus type I and adult T-cell leukemia , 2003, Oncogene.

[6]  Minh N. H. Nguyen,et al.  The PDZ Ligand Domain of the Human Papillomavirus Type 16 E6 Protein Is Required for E6's Induction of Epithelial Hyperplasia In Vivo , 2003, Journal of Virology.

[7]  M. Tomonaga,et al.  Bay 11-7082 inhibits transcription factor NF-kappaB and induces apoptosis of HTLV-I-infected T-cell lines and primary adult T-cell leukemia cells. , 2002, Blood.

[8]  F. Kashanchi,et al.  Activation of cyclin D1 and D2 promoters by human T‐cell leukemia virus type I tax protein is associated with IL‐2–independent growth of T cells , 2002, International journal of cancer.

[9]  M. Fukushi,et al.  Human T-Cell Leukemia Virus Type 2 (HTLV-2) Tax Protein Transforms a Rat Fibroblast Cell Line but Less Efficiently than HTLV-1 Tax , 2002, Journal of Virology.

[10]  K. Ohtani,et al.  Molecular mechanism of cell cycle progression induced by the oncogene product Tax of human T-cell leukemia virus type I , 2001, Oncogene.

[11]  M. Salemi,et al.  Isolation, cloning, and complete nucleotide sequence of a phenotypically distinct Brazilian isolate of human T-lymphotropic virus type II (HTLV-II). , 2000, Virology.

[12]  K. Ohtani,et al.  Cell Type-specific E2F Activation and Cell Cycle Progression Induced by the Oncogene Product Tax of Human T-cell Leukemia Virus Type I* , 2000, The Journal of Biological Chemistry.

[13]  T. Akiyama,et al.  Tax oncoprotein of HTLV-1 binds to the human homologue of Drosophila discs large tumor suppressor protein, hDLG, and perturbs its function in cell growth control , 1999, Oncogene.

[14]  M. Kannagi,et al.  Induction of Bcl-xL Expression by Human T-Cell Leukemia Virus Type 1 Tax through NF-κB in Apoptosis-Resistant T-Cell Transfectants with Tax , 1999, Journal of Virology.

[15]  L. Ratner,et al.  Immortalization of CD4+ and CD8+ T Lymphocytes by Human T-Cell Leukemia Virus Type 1 Tax Mutants Expressed in a Functional Molecular Clone , 1999, Journal of Virology.

[16]  Yuetsu Tanaka,et al.  Human T-Cell Leukemia Virus Type 1 Tax Protein Abrogates Interleukin-2 Dependence in a Mouse T-Cell Line , 1999, Journal of Virology.

[17]  R. Rousset,et al.  The C-terminus of the HTLV-1 Tax oncoprotein mediates interaction with the PDZ domain of cellular proteins , 1998, Oncogene.

[18]  M Fujita,et al.  Binding of high-risk human papillomavirus E6 oncoproteins to the human homologue of the Drosophila discs large tumor suppressor protein. , 1997, Proceedings of the National Academy of Sciences of the United States of America.

[19]  K. Jeang,et al.  Human T-cell leukemia virus type 1 Tax releases cell cycle arrest induced by p16INK4a , 1997, Journal of virology.

[20]  T. Ross,et al.  The tax gene of human T-cell leukemia virus type 2 is essential for transformation of human T lymphocytes , 1996, Journal of virology.

[21]  K. Shimotohno,et al.  Expression of cell-cycle regulatory genes in HTLV-I infected T-cell lines: possible involvement of Tax1 in the altered expression of cyclin D2, p18Ink4 and p21Waf1/Cip1/Sdi1. , 1996, Oncogene.

[22]  T. Ley,et al.  Development of leukemia in mice transgenic for the tax gene of human T-cell leukemia virus type I. , 1995, Proceedings of the National Academy of Sciences of the United States of America.

[23]  J. Heeney,et al.  Inhibition of apoptosis in T cells expressing human T cell leukemia virus type I Tax. , 1994, AIDS research and human retroviruses.

[24]  K. Shimotohno,et al.  Proliferative response of Tax1-transduced primary human T cells to anti-CD3 antibody stimulation by an interleukin-2-independent pathway , 1993, Journal of virology.

[25]  K. Sugamura,et al.  Human Retroviruses: HTLV-I and HTLV-II , 1993 .

[26]  J. Sodroski,et al.  Role of human T-cell leukemia virus type 1 X region proteins in immortalization of primary human lymphocytes in culture , 1992, Journal of virology.

[27]  Yuetsu Tanaka,et al.  Production of a recombinant human T‐cell leukemia virus type‐I trans‐activator (tax1) antigen and its utilization for generation of monoclonal antibodies against various epitopes on the tax1 antigen , 1991, International journal of cancer.

[28]  N. Nomura,et al.  HTLV-1 Tax induces expression of various immediate early serum responsive genes. , 1991, Oncogene.

[29]  B. Franza,et al.  HTLV-I tax induces cellular proteins that activate the kappa B element in the IL-2 receptor alpha gene. , 1988, Science.

[30]  R. K. Reynolds,et al.  The tat gene of human T-lymphotropic virus type 1 induces mesenchymal tumors in transgenic mice. , 1987, Science.

[31]  S. L. Cross,et al.  Regulation of the human interleukin-2 receptor α chain promoter: Activation of a nonfunctional promoter by the transactivator gene of HTLV-I , 1987, Cell.

[32]  T. Taniguchi,et al.  Evidence for aberrant activation of the interleukin-2 autocrine loop by HTLV-1-encoded p40x and T3/Ti complex triggering , 1987, Cell.

[33]  T. Taniguchi,et al.  Induction of interleukin 2 receptor gene expression by p40x encoded by human T‐cell leukemia virus type 1. , 1986, The EMBO journal.

[34]  M. Yoshida,et al.  Direct evidence that p40x of human T‐cell leukemia virus type I is a trans‐acting transcriptional activator. , 1986, The EMBO journal.

[35]  W. Wachsman,et al.  The x gene is essential for HTLV replication. , 1985, Science.

[36]  S. Quan,et al.  Human T-cell leukemia virus type II transforms normal human lymphocytes. , 1983, Proceedings of the National Academy of Sciences of the United States of America.

[37]  D. Golde,et al.  Molecular characterization of genome of a novel human T-cell leukaemia virus , 1983, Nature.

[38]  M. Yoshida,et al.  Human adult T-cell leukemia virus: complete nucleotide sequence of the provirus genome integrated in leukemia cell DNA. , 1983, Proceedings of the National Academy of Sciences of the United States of America.

[39]  M. Kannagi,et al.  Transformation of human leukocytes by cocultivation with an adult T cell leukemia virus producer cell line. , 1982, Science.

[40]  Y. Ohtsuki,et al.  Type C virus particles in a cord T-cell line derived by co-cultivating normal human cord leukocytes and human leukaemic T cells , 1981, Nature.

[41]  John D. Minna,et al.  Detection and isolation of type C retrovirus particles from fresh and cultured lymphocytes of a patient with cutaneous T-cell lymphoma , 1980, Proceedings of the National Academy of Sciences.

[42]  J. Yodoi,et al.  Adult T-cell leukemia: clinical and hematologic features of 16 cases. , 1977, Blood.

[43]  H. Towler,et al.  Adult T-cell leukemia : antigen in an ATL cell line and detection of antibodies to the antigen in human sera , 2022 .