Application of an ion mobility spectrometer with pulsed ionisation source in the detection of dimethyl methylphosphonate and toluene diisocyanate

Ion mobility spectrometry (IMS) is a well known technique; offering small size and a sensitivity in the ppb range makes it a typical technique for the detection of explosives or chemical warfare agents. Ordinary IMS devices use in general a continuously working radioactive ionization source. We use a pulsed non-radioactive electron source for ionization which offers the innovative possibility of introducing delay times in between ionization and ion detection. The application and benefits of such a pulsed ionization source in the detection of the chemical warfare agent simulant dimethyl methylphosphonate (DMMP) and the toxic toluene diisocyanate (TDI) will be demonstrated.

[1]  Facundo M Fernandez,et al.  Recent developments in ambient ionization techniques for analytical mass spectrometry. , 2008, The Analyst.

[2]  W. Baether,et al.  Application of a nonradioactive pulsed electron source for ion mobility spectrometry. , 2010, Analytical chemistry.

[3]  Joseph E. Roehl,et al.  Environmental and Process Applications for Ion Mobility Spectrometry , 1991 .

[4]  J. L. Brokenshire,et al.  Near Real Time Monitoring of TDI Vapour Using Ion Mobility Spectrometry (IMS)* , 1990 .

[5]  W. Baether,et al.  Investigation of the influence of voltage parameters on decay times in an ion mobility spectrometer with a pulsed non-radioactive electron source , 2010 .

[6]  Albert Simon,et al.  The Mobility and Diffusion of Ions in Gases , 1975 .

[7]  T. Yamagaki,et al.  Isomeric Oligosaccharides Analyses Using Negative-ion Electrospray Ionization Ion Mobility Spectrometry Combined with Collision-induced Dissociation MS/MS , 2009, Analytical sciences : the international journal of the Japan Society for Analytical Chemistry.

[8]  A. Langmeier,et al.  Hydrocarbon detection using laser ion mobility spectrometry , 2009 .

[9]  Z. Karpas,et al.  Ion mobility spectrometry , 1993, Breathborne Biomarkers and the Human Volatilome.

[10]  Gary A. Eiceman,et al.  Ion-mobility spectrometry as a fast monitor of chemical composition , 2002 .

[11]  Herbert H Hill,et al.  Detection of a chemical warfare agent simulant in various aerosol matrixes by ion mobility time-of-flight mass spectrometry. , 2005, Analytical chemistry.

[12]  H. Hill,et al.  Ion Mobility Spectrometry: Ion Source Development and Applications in Physical and Biological Sciences , 2008, IEEE Transactions on Plasma Science.