Rac regulates integrin-mediated endothelial cell adhesion and migration on laminin-8.

[1]  S. Jacobsen,et al.  Laminin isoform-specific promotion of adhesion and migration of human bone marrow progenitor cells. , 2003, Blood.

[2]  Kayla J Bayless,et al.  Molecular basis of endothelial cell morphogenesis in three‐dimensional extracellular matrices , 2002, The Anatomical record.

[3]  K. Tryggvason,et al.  Chondroitin sulphate modification in the α4 chain of human recombinant laminin-8 (α4β1γ1) , 2002 .

[4]  K. Sekiguchi,et al.  Localization of Laminin α4-Chain in Developing and Adult Human Tissues , 2002 .

[5]  A. Hall,et al.  Rac regulates endothelial morphogenesis and capillary assembly. , 2002, Molecular biology of the cell.

[6]  R. Timpl,et al.  Recombinant human laminin-10 (alpha5beta1gamma1). Production, purification, and migration-promoting activity on vascular endothelial cells. , 2002, The Journal of biological chemistry.

[7]  G. Davis,et al.  The Cdc42 and Rac1 GTPases are required for capillary lumen formation in three-dimensional extracellular matrices. , 2002, Journal of cell science.

[8]  M. Risling,et al.  Deletion of the Laminin α4 Chain Leads to Impaired Microvessel Maturation , 2002, Molecular and Cellular Biology.

[9]  D. Cheresh,et al.  Adhesion events in angiogenesis. , 2001, Current opinion in cell biology.

[10]  M. Sixt,et al.  Cell Adhesion and Migration Properties of β2-Integrin Negative Polymorphonuclear Granulocytes on Defined Extracellular Matrix Molecules , 2001, The Journal of Biological Chemistry.

[11]  B. Engelhardt,et al.  Endothelial Cell Laminin Isoforms, Laminins 8 and 10, Play Decisive Roles in T Cell Recruitment across the Blood–Brain Barrier in Experimental Autoimmune Encephalomyelitis , 2001, The Journal of cell biology.

[12]  K. Sekiguchi,et al.  Purification and Characterization of Human Laminin-8 , 2001, The Journal of Biological Chemistry.

[13]  R. Kiessling,et al.  Laminin-8 (alpha4beta1gamma1) is synthesized by lymphoid cells, promotes lymphocyte migration and costimulates T cell proliferation. , 2001, Journal of cell science.

[14]  K. Tryggvason,et al.  Monocytic Cells Synthesize, Adhere to, and Migrate on Laminin-8 (α4β1γ1)1 , 2000, The Journal of Immunology.

[15]  R. Burgeson,et al.  Laminin Expression in Adult and Developing Retinae: Evidence of Two Novel CNS Laminins , 2000, The Journal of Neuroscience.

[16]  T. Sasaki,et al.  Structure and function of laminin LG modules. , 2000, Matrix biology : journal of the International Society for Matrix Biology.

[17]  T. Kiviluoto,et al.  Laminin alpha1-chain shows a restricted distribution in epithelial basement membranes of fetal and adult human tissues. , 2000, Experimental cell research.

[18]  P. Yurchenco,et al.  Form and function: The laminin family of heterotrimers , 2000, Developmental dynamics : an official publication of the American Association of Anatomists.

[19]  K. Tryggvason,et al.  Recombinant Laminin-8 (α4β1γ1) , 2000, The Journal of Biological Chemistry.

[20]  M. Grounds,et al.  Laminin alpha4 and integrin alpha6 are upregulated in regenerating dy/dy skeletal muscle: comparative expression of laminin and integrin isoforms in muscles regenerating after crush injury. , 2000, Experimental cell research.

[21]  A. Sonnenberg,et al.  Integrin binding specificity of laminin-10/11: laminin-10/11 are recognized by alpha 3 beta 1, alpha 6 beta 1 and alpha 6 beta 4 integrins. , 2000, Journal of cell science.

[22]  E. Forsberg,et al.  Restricted distribution of laminin α1 chain in normal adult mouse tissues , 1999 .

[23]  E. Engvall,et al.  Blood Platelets Contain and Secrete Laminin-8 (α4β1γ1) and Adhere to Laminin-8 via α6β1 Integrin , 1999 .

[24]  John G. Collard,et al.  Rac Downregulates Rho Activity: Reciprocal Balance between Both Gtpases Determines Cellular Morphology and Migratory Behavior , 1999 .

[25]  K. Rottner,et al.  Interplay between Rac and Rho in the control of substrate contact dynamics , 1999, Current Biology.

[26]  A. Huttenlocher,et al.  Regulation of integrin‐mediated adhesion during cell migration , 1998, Microscopy research and technique.

[27]  R. Yauch,et al.  Highly stoichiometric, stable, and specific association of integrin alpha3beta1 with CD151 provides a major link to phosphatidylinositol 4-kinase, and may regulate cell migration. , 1998, Molecular biology of the cell.

[28]  M. Durbeej,et al.  Laminin Isoforms and Epithelial Development , 1998, Annals of the New York Academy of Sciences.

[29]  K. Sekiguchi,et al.  Isolation and Characterization of Laminin-10/11 Secreted by Human Lung Carcinoma Cells , 1998, The Journal of Biological Chemistry.

[30]  Sean P. Palecek,et al.  Physical and biochemical regulation of integrin release during rear detachment of migrating cells. , 1998, Journal of cell science.

[31]  J. Sanes,et al.  Distribution and Function of Laminins in the Neuromuscular System of Developing, Adult, and Mutant Mice , 1997, The Journal of cell biology.

[32]  K. Sekiguchi,et al.  Modulation of Cell-adhesive Activity of Fibronectin by the Alternatively Spliced EDA Segment , 1997, The Journal of cell biology.

[33]  M. Okano,et al.  Differentiation-dependent expression of laminin-8 (α4β1γ1) mRNAs in mouse 3T3-L1 adipocytes☆ , 1997 .

[34]  S. Kröger,et al.  Developmental regulation of the laminin alpha5 chain suggests a role in epithelial and endothelial cell maturation. , 1997, Developmental biology.

[35]  J. Sanes,et al.  The Laminin α Chains: Expression, Developmental Transitions, and Chromosomal Locations of α1-5, Identification of Heterotrimeric Laminins 8–11, and Cloning of a Novel α3 Isoform , 1997, The Journal of cell biology.

[36]  K. Franssila,et al.  Changes in the distribution of integrins and their basement membrane ligands during development of human thyroid follicular epithelium , 1997, The Histochemical Journal.

[37]  J. Sanes,et al.  Molecular Cloning of a Novel Laminin Chain, α5, and Widespread Expression in Adult Mouse Tissues (*) , 1995, The Journal of Biological Chemistry.

[38]  K. Tryggvason,et al.  Primary structure and expression of a novel human laminin α4 chain , 1995 .

[39]  R. Burgeson,et al.  The dermal-epidermal junction of human skin contains a novel laminin variant , 1992, The Journal of cell biology.

[40]  W. Carter,et al.  Epiligrin, a new cell adhesion ligand for integrin α3β1 in epithelial basement membranes , 1991, Cell.

[41]  A. Sonnenberg,et al.  Association of the VLA alpha 6 subunit with a novel protein. A possible alternative to the common VLA beta 1 subunit on certain cell lines. , 1989, The Journal of biological chemistry.

[42]  A. Sonnenberg,et al.  Identification and characterization of a novel antigen complex on mouse mammary tumor cells using a monoclonal antibody against platelet glycoprotein Ic. , 1988, The Journal of biological chemistry.

[43]  E. Engvall,et al.  Merosin, a protein specific for basement membranes of Schwann cells, striated muscle, and trophoblast, is expressed late in nerve and muscle development. , 1988, Proceedings of the National Academy of Sciences of the United States of America.

[44]  R. Timpl,et al.  Laminin-nidogen complex. Extraction with chelating agents and structural characterization. , 1987, European journal of biochemistry.

[45]  J A Madri,et al.  Endothelial cell proliferation during angiogenesis. In vitro modulation by basement membrane components. , 1986, Laboratory investigation; a journal of technical methods and pathology.

[46]  K. Sekiguchi,et al.  Domain structure of human plasma fibronectin. Differences and similarities between human and hamster fibronectins. , 1983, The Journal of biological chemistry.

[47]  E. Jaffe,et al.  Culture of human endothelial cells derived from umbilical veins. Identification by morphologic and immunologic criteria. , 1973, The Journal of clinical investigation.

[48]  U. K. Laemmli,et al.  Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4 , 1970, Nature.

[49]  K. Sekiguchi,et al.  Laminin gamma2-chain fragment in the circulation: a prognostic indicator of epithelial tumor invasion. , 2003, Cancer research.

[50]  M. Hemler,et al.  Function of the Tetraspanin CD151–α6β1 Integrin Complex during Cellular Morphogenesis , 2002 .

[51]  A. Sonnenberg,et al.  Integrin binding specificity of laminin-10/11: laminin-10/11 are recognized by α3β1, α6β1 and α6β4 integrins , 2000 .

[52]  H. Kleinman,et al.  Regulation of capillary formation by laminin and other components of the extracellular matrix. , 1997, EXS.