Simplified Process of Obstructive Sleep Apnea Detection Using ECG Signal Based Analysis with Data Flow Programming

The work is focused on detection of Obstructive Sleep apnea (OSA), a condition of cessation of breathing during night sleep caused by blockage of upper respiratory tract in an individual. ElectroCardioGram (ECG) signal is one of the clinically established procedures that can be relied on for deciding on the presence or absence of sleep apnea along with its severity in the subject at an earlier stage, so that the expert can advise for the relevant treatment. Earlier detection of OSA, can avoid the severe consequences leading to hypertension, Atrial-Fibrillation and day-time sleepiness that can affect the patient. ECG signal recordings from Apnea database from Physiobank, MIT website have been used for the purpose. The ECG signal based methods like QRS complex detection, RR interval variability, Respiratory Variability, Heart rate variability parameters used to detect OSA are compared and evaluated in order to select the most accurate method. Here we present the stepwise procedures, results and analysis of implementation methods used for detection of sleep apnea based on ECG signal using robust dataflow programming feature available in LabVIEW2014. Results indicate that accuracy, specificity and sensitivity of Heart Rate based detection method of OSA are 83%, 75% and 88% respectively and thus rated as one of the simple and reliable ways of detecting OSA.

[1]  Yu Hen Hu,et al.  Power-Line Interference Detection and Suppression in ECG Signal Processing , 2008, IEEE Transactions on Biomedical Engineering.

[2]  G. Moody,et al.  Clinical Validation of the ECG-Derived Respiration (EDR) Technique , 2008 .

[3]  Mehrdad Nourani,et al.  Wavelet-based denoising and beat detection of ECG signal , 2009, 2009 IEEE/NIH Life Science Systems and Applications Workshop.

[4]  Donghui Zhang,et al.  Wavelet Approach for ECG Baseline Wander Correction and Noise Reduction , 2005, 2005 IEEE Engineering in Medicine and Biology 27th Annual Conference.

[5]  Jie Zhao,et al.  Derivation of Respiratory Signals from Single-Lead ECG , 2008, 2008 International Seminar on Future BioMedical Information Engineering.

[6]  Rangaraj M. Rangayyan,et al.  Biomedical Signal Analysis , 2015 .

[7]  Willis J. Tompkins,et al.  A Real-Time QRS Detection Algorithm , 1985, IEEE Transactions on Biomedical Engineering.

[8]  Shivaram P. Arunachalam,et al.  Real-time estimation of the ECG-derived respiration (EDR) signal using a new algorithm for baseline wander noise removal , 2009, 2009 Annual International Conference of the IEEE Engineering in Medicine and Biology Society.

[9]  George B. Moody,et al.  Derivation of Respiratory Signals from Multi-lead ECGs , 2008 .

[10]  James D. Broesch Digital Signal Processing Demystified , 1997 .

[11]  E. W. Hancock,et al.  Recommendations for the standardization and interpretation of the electrocardiogram: part II: Electrocardiography diagnostic statement list: a scientific statement from the American Heart Association Electrocardiography and Arrhythmias Committee, Council on Clinical Cardiology; the American College , 2007, Circulation.