Candida albicans Hyphal Formation and the Expression of the Efg1-Regulated Proteinases Sap4 to Sap6 Are Required for the Invasion of Parenchymal Organs
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M. Schaller | T. Nichterlein | B. Hube | H. Korting | D. Sanglard | W. Schäfer | M. Kretschmar | A. Felk | A. Albrecht | S. Beinhauer | Antje Albrecht
[1] D. Soll,et al. A characterization of pH-regulated dimorphism in Candida albicans , 1984, Mycopathologia.
[2] A. Gillum,et al. Isolation of the Candida albicans gene for orotidine-5′-phosphate decarboxylase by complementation of S. cerevisiae ura3 and E. coli pyrF mutations , 2004, Molecular and General Genetics MGG.
[3] M. Schaller,et al. Individual acid aspartic proteinases (Saps) 1-6 of Candida albicans are not essential for invasion and colonization of the gastrointestinal tract in mice. , 2002, Microbial pathogenesis.
[4] B. Hube,et al. Candida albicans proteinases: resolving the mystery of a gene family. , 2001, Microbiology.
[5] Gerald R. Fink,et al. The glyoxylate cycle is required for fungal virulence , 2001, Nature.
[6] L. Hoyer,et al. The ALS gene family of Candida albicans. , 2001, Trends in microbiology.
[7] M. Whiteway,et al. Repression of Hyphal Proteinase Expression by the Mitogen-Activated Protein (MAP) Kinase Phosphatase Cpp1p ofCandida albicans Is Independent of the MAP Kinase Cek1p , 2000, Infection and Immunity.
[8] B. Hube,et al. Secreted lipases of Candida albicans: cloning, characterisation and expression analysis of a new gene family with at least ten members , 2000, Archives of Microbiology.
[9] J. Ernst. Transcription factors in Candida albicans - environmental control of morphogenesis. , 2000, Microbiology.
[10] S. Foundling,et al. Enzymic characteristics of secreted aspartic proteases of Candida albicans. , 2000, Biochimica et biophysica acta.
[11] S. Filler,et al. Role of Hyphal Formation in Interactions ofCandida albicans with Endothelial Cells , 2000, Infection and Immunity.
[12] T. Nichterlein,et al. Differential activation of a Candida albicans virulence gene family during infection. , 2000, Proceedings of the National Academy of Sciences of the United States of America.
[13] A. Brown,et al. CIp10, an efficient and convenient integrating vector for Candida albicans. , 2000, Yeast.
[14] T. Bertsch,et al. Germ Tubes and Proteinase Activity Contribute to Virulence of Candida albicans in Murine Peritonitis , 1999, Infection and Immunity.
[15] M. Schaller,et al. Secreted aspartic proteinase (Sap) activity contributes to tissue damage in a model of human oral candidosis , 1999, Molecular microbiology.
[16] P. Sundstrom,et al. Adhesins in Candida albicans. , 1999, Current opinion in microbiology.
[17] A. Brown,et al. Regulatory networks controlling Candida albicans morphogenesis. , 1999, Trends in microbiology.
[18] T. C. White,et al. In Vivo Analysis of Secreted Aspartyl Proteinase Expression in Human Oral Candidiasis , 1999, Infection and Immunity.
[19] D. Sanglard,et al. Evidence that members of the secretory aspartyl proteinase gene family, in particular SAP2, are virulence factors for Candida vaginitis. , 1999, The Journal of infectious diseases.
[20] J. Becker,et al. Altered Expression of Selectable Marker URA3 in Gene-Disrupted Candida albicans Strains Complicates Interpretation of Virulence Studies , 1998, Infection and Immunity.
[21] D. Hess,et al. Differential regulation of SAP8 and SAP9, which encode two new members of the secreted aspartic proteinase family in Candida albicans. , 1998, Microbiology.
[22] M. Schaller,et al. Differential expression of secreted aspartyl proteinases in a model of human oral candidosis and in patient samples from the oral cavity , 1998, Molecular microbiology.
[23] K. Boggian,et al. The expression of the secreted aspartyl proteinases Sap4 to Sap6 from Candida albicans in murine macrophages , 1998, Molecular microbiology.
[24] S. Kobayashi,et al. Candida albicans hyphal formation and virulence: is there a clearly defined role? , 1998, Trends in microbiology.
[25] J. Berman,et al. Linkage of adhesion, filamentous growth, and virulence in Candida albicans to a single gene, INT1. , 1998, Science.
[26] G. Fink,et al. Nonfilamentous C. albicans Mutants Are Avirulent , 1997, Cell.
[27] N. Gow,et al. A triple deletion of the secreted aspartyl proteinase genes SAP4, SAP5, and SAP6 of Candida albicans causes attenuated virulence , 1997, Infection and immunity.
[28] A. Brown,et al. Disruption of each of the secreted aspartyl proteinase genes SAP1, SAP2, and SAP3 of Candida albicans attenuates virulence , 1997, Infection and immunity.
[29] J. Ernst,et al. Efg1p, an essential regulator of morphogenesis of the human pathogen Candida albicans, is a member of a conserved class of bHLH proteins regulating morphogenetic processes in fungi , 1997, The EMBO journal.
[30] D. Soll. Gene regulation during high-frequency switching in Candida albicans. , 1997, Microbiology.
[31] D. Gozalbo,et al. Molecular cloning and characterization of a Candida albicans gene (EFB1) coding for the elongation factor EF-1β , 1996 .
[32] J. Ernst,et al. Migration of the fungal pathogen Candida albicans across endothelial monolayers , 1996, Infection and immunity.
[33] D. Gozalbo,et al. Molecular cloning and characterization of a Candida albicans gene (EFB1) coding for the elongation factor EF-1 beta. , 1996, FEMS Microbiology Letters.
[34] T. C. White,et al. Candida albicans secreted aspartyl proteinases: isoenzyme pattern is determined by cell type, and levels are determined by environmental factors , 1995, Journal of bacteriology.
[35] M. Ghannoum,et al. Evidence implicating phospholipase as a virulence factor of Candida albicans , 1995, Infection and immunity.
[36] A. Brown,et al. Expression of seven members of the gene family encoding secretory aspartyl proteinases in Candida albicans , 1994, Molecular microbiology.
[37] B. Hube,et al. Multiplicity of genes encoding secreted aspartic proteinases in Candida species , 1994, Molecular microbiology.
[38] D. Irwin,et al. Isogenic strain construction and gene mapping in Candida albicans. , 1993, Genetics.
[39] N. Gow,et al. Contact sensing in Candida albicans: a possible aid to epithelial penetration. , 1992, Journal of medical and veterinary mycology : bi-monthly publication of the International Society for Human and Animal Mycology.
[40] J. Cutler,et al. Putative virulence factors of Candida albicans. , 1991, Annual review of microbiology.
[41] N. Gow,et al. Growth kinetics and morphology of colonies of the filamentous form of Candida albicans. , 1982, Journal of general microbiology.
[42] F. Macdonald,et al. Purified Candida albicans proteinase in the serological diagnosis of systemic candidosis. , 1980, JAMA.
[43] F. Odds,et al. Candida and candidosis , 1979 .
[44] D. Soll,et al. A characterization of pH-regulated dimorphism in Candida albicans , 1984, Mycopathologia.
[45] A. Gillum,et al. Isolation of the Candida albicans gene for orotidine-5′-phosphate decarboxylase by complementation of S. cerevisiae ura3 and E. coli pyrF mutations , 2004, Molecular and General Genetics MGG.
[46] M. Schaller,et al. Individual acid aspartic proteinases (Saps) 1-6 of Candida albicans are not essential for invasion and colonization of the gastrointestinal tract in mice. , 2002, Microbial pathogenesis.
[47] B. Hube,et al. Candida albicans proteinases: resolving the mystery of a gene family. , 2001, Microbiology.
[48] Gerald R. Fink,et al. The glyoxylate cycle is required for fungal virulence , 2001, Nature.
[49] L. Hoyer,et al. The ALS gene family of Candida albicans. , 2001, Trends in microbiology.
[50] M. Whiteway,et al. Repression of Hyphal Proteinase Expression by the Mitogen-Activated Protein (MAP) Kinase Phosphatase Cpp1p ofCandida albicans Is Independent of the MAP Kinase Cek1p , 2000, Infection and Immunity.
[51] B. Hube,et al. Secreted lipases of Candida albicans: cloning, characterisation and expression analysis of a new gene family with at least ten members , 2000, Archives of Microbiology.
[52] J. Ernst. Transcription factors in Candida albicans - environmental control of morphogenesis. , 2000, Microbiology.
[53] S. Foundling,et al. Enzymic characteristics of secreted aspartic proteases of Candida albicans. , 2000, Biochimica et biophysica acta.
[54] S. Filler,et al. Role of Hyphal Formation in Interactions ofCandida albicans with Endothelial Cells , 2000, Infection and Immunity.
[55] T. Nichterlein,et al. Differential activation of a Candida albicans virulence gene family during infection. , 2000, Proceedings of the National Academy of Sciences of the United States of America.
[56] A. Brown,et al. CIp10, an efficient and convenient integrating vector for Candida albicans. , 2000, Yeast.
[57] T. Bertsch,et al. Germ Tubes and Proteinase Activity Contribute to Virulence of Candida albicans in Murine Peritonitis , 1999, Infection and Immunity.
[58] M. Schaller,et al. Secreted aspartic proteinase (Sap) activity contributes to tissue damage in a model of human oral candidosis , 1999, Molecular microbiology.
[59] P. Sundstrom,et al. Adhesins in Candida albicans. , 1999, Current opinion in microbiology.
[60] A. Brown,et al. Regulatory networks controlling Candida albicans morphogenesis. , 1999, Trends in microbiology.
[61] T. C. White,et al. In Vivo Analysis of Secreted Aspartyl Proteinase Expression in Human Oral Candidiasis , 1999, Infection and Immunity.
[62] D. Sanglard,et al. Evidence that members of the secretory aspartyl proteinase gene family, in particular SAP2, are virulence factors for Candida vaginitis. , 1999, The Journal of infectious diseases.
[63] J. Becker,et al. Altered Expression of Selectable Marker URA3 in Gene-Disrupted Candida albicans Strains Complicates Interpretation of Virulence Studies , 1998, Infection and Immunity.
[64] D. Hess,et al. Differential regulation of SAP8 and SAP9, which encode two new members of the secreted aspartic proteinase family in Candida albicans. , 1998, Microbiology.
[65] M. Schaller,et al. Differential expression of secreted aspartyl proteinases in a model of human oral candidosis and in patient samples from the oral cavity , 1998, Molecular microbiology.
[66] K. Boggian,et al. The expression of the secreted aspartyl proteinases Sap4 to Sap6 from Candida albicans in murine macrophages , 1998, Molecular microbiology.
[67] S. Kobayashi,et al. Candida albicans hyphal formation and virulence: is there a clearly defined role? , 1998, Trends in microbiology.
[68] J. Berman,et al. Linkage of adhesion, filamentous growth, and virulence in Candida albicans to a single gene, INT1. , 1998, Science.
[69] G. Fink,et al. Nonfilamentous C. albicans Mutants Are Avirulent , 1997, Cell.
[70] N. Gow,et al. A triple deletion of the secreted aspartyl proteinase genes SAP4, SAP5, and SAP6 of Candida albicans causes attenuated virulence , 1997, Infection and immunity.
[71] J. Ernst,et al. Efg1p, an essential regulator of morphogenesis of the human pathogen Candida albicans, is a member of a conserved class of bHLH proteins regulating morphogenetic processes in fungi , 1997, The EMBO journal.
[72] D. Soll. Gene regulation during high-frequency switching in Candida albicans. , 1997, Microbiology.
[73] A. Brown,et al. Disruption of each of the secreted aspartyl proteinase genes SAP1, SAP2, and SAP3 of Candida albicans attenuates virulence , 1997, Infection and immunity.
[74] J. Ernst,et al. Migration of the fungal pathogen Candida albicans across endothelial monolayers , 1996, Infection and immunity.
[75] D. Gozalbo,et al. Molecular cloning and characterization of a Candida albicans gene (EFB1) coding for the elongation factor EF-1 beta. , 1996, FEMS Microbiology Letters.
[76] T. C. White,et al. Candida albicans secreted aspartyl proteinases: isoenzyme pattern is determined by cell type, and levels are determined by environmental factors , 1995, Journal of bacteriology.
[77] M. Ghannoum,et al. Evidence implicating phospholipase as a virulence factor of Candida albicans , 1995, Infection and immunity.
[78] A. Brown,et al. Expression of seven members of the gene family encoding secretory aspartyl proteinases in Candida albicans , 1994, Molecular microbiology.
[79] B. Hube,et al. Multiplicity of genes encoding secreted aspartic proteinases in Candida species , 1994, Molecular microbiology.
[80] D. Irwin,et al. Isogenic strain construction and gene mapping in Candida albicans. , 1993, Genetics.
[81] N. Gow,et al. Contact sensing in Candida albicans: a possible aid to epithelial penetration. , 1992, Journal of medical and veterinary mycology : bi-monthly publication of the International Society for Human and Animal Mycology.
[82] J. Cutler,et al. Putative virulence factors of Candida albicans. , 1991, Annual review of microbiology.
[83] F. Odds. Candida and candidosis: a review and bibliography. 2nd edition. , 1988 .
[84] N. Gow,et al. Growth kinetics and morphology of colonies of the filamentous form of Candida albicans. , 1982, Journal of general microbiology.
[85] F. Macdonald,et al. Purified Candida albicans proteinase in the serological diagnosis of systemic candidosis. , 1980, JAMA.
[86] F. Odds,et al. Candida and candidosis , 1979 .