The anaphase-promoting complex: proteolysis in mitosis and beyond.
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[1] S. Prinz,et al. CDC20 and CDH1: a family of substrate-specific activators of APC-dependent proteolysis. , 1997, Science.
[2] J. Peters,et al. Three-dimensional structure of the anaphase-promoting complex. , 2001, Molecular cell.
[3] J. R. Daum,et al. Mammalian p55CDC Mediates Association of the Spindle Checkpoint Protein Mad2 with the Cyclosome/Anaphase-promoting Complex, and is Involved in Regulating Anaphase Onset and Late Mitotic Events , 1998, The Journal of cell biology.
[4] A. Murray,et al. A novel yeast screen for mitotic arrest mutants identifies DOC1, a new gene involved in cyclin proteolysis. , 1997, Molecular biology of the cell.
[5] Angelika Amon,et al. Separase, Polo Kinase, the Kinetochore Protein Slk19, and Spo12 Function in a Network that Controls Cdc14 Localization during Early Anaphase , 2002, Cell.
[6] Kim Nasmyth,et al. The Polo‐like kinase Cdc5p and the WD‐repeat protein Cdc20p/fizzy are regulators and substrates of the anaphase promoting complex in Saccharomyces cerevisiae , 1998, The EMBO journal.
[7] M. Mann,et al. The RING-H2 finger protein APC11 and the E2 enzyme UBC4 are sufficient to ubiquitinate substrates of the anaphase-promoting complex. , 2000, Proceedings of the National Academy of Sciences of the United States of America.
[8] J. Peters,et al. Ubiquitin and the Biology of the Cell , 1998, Springer US.
[9] Andrew W. Murray,et al. Phosphorylation by Cdc28 Activates the Cdc20-Dependent Activity of the Anaphase-Promoting Complex , 2000, The Journal of cell biology.
[10] Budding yeast Cdc20 , 1998 .
[11] S. Artavanis-Tsakonas,et al. The Drosophila cell cycle gene fizzy is required for normal degradation of cyclins A and B during mitosis and has homology to the CDC20 gene of Saccharomyces cerevisiae , 1995, The Journal of cell biology.
[12] M. Kirschner,et al. Identification of a cullin homology region in a subunit of the anaphase-promoting complex. , 1998, Science.
[13] M. Hoyt,et al. Cell cycle-dependent degradation of the Saccharomyces cerevisiae spindle motor Cin8p requires APC(Cdh1) and a bipartite destruction sequence. , 2001, Molecular biology of the cell.
[14] R. Bernards,et al. Distinct Initiation and Maintenance Mechanisms Cooperate to Induce G1 Cell Cycle Arrest in Response to DNA Damage , 2000, Cell.
[15] M. Kirschner,et al. A 20s complex containing CDC27 and CDC16 catalyzes the mitosis-specific conjugation of ubiquitin to cyclin B , 1995, Cell.
[16] J. Peters,et al. Cell Cycle Control by Ubiquitin-Dependent Proteolysis , 1998 .
[17] K. Helin,et al. Mad2 binding to Mad1 and Cdc20, rather than oligomerization, is required for the spindle checkpoint , 2001, The EMBO journal.
[18] Friedrich Lottspeich,et al. Sister-chromatid separation at anaphase onset is promoted by cleavage of the cohesin subunit Scc1 , 1999, Nature.
[19] Leslie Wilson,et al. Mammalian mad2 and bub1/bubR1 recognize distinct spindle-attachment and kinetochore-tension checkpoints , 2001, Proceedings of the National Academy of Sciences of the United States of America.
[20] J. Peters,et al. APC-Mediated Proteolysis of Ase1 and the Morphogenesis of the Mitotic Spindle , 1997, Science.
[21] O. Cohen-Fix,et al. The anaphase inhibitor Pds1 binds to the APC/C-associated protein Cdc20 in a destruction box-dependent manner , 2001, Current Biology.
[22] J. Peters,et al. A Conserved Cyclin-Binding Domain Determines Functional Interplay between Anaphase-Promoting Complex–Cdh1 and Cyclin A-Cdk2 during Cell Cycle Progression , 2001, Molecular and Cellular Biology.
[23] M. Kirschner,et al. Identification of multiple CDH1 homologues in vertebrates conferring different substrate specificities , 2001, Proceedings of the National Academy of Sciences of the United States of America.
[24] J. Wrana,et al. Smad3 recruits the anaphase-promoting complex for ubiquitination and degradation of SnoN. , 2001, Genes & development.
[25] A. Amon. The spindle checkpoint. , 1999, Current opinion in genetics & development.
[26] G. Chan,et al. Checkpoint inhibition of the APC/C in HeLa cells is mediated by a complex of BUBR1, BUB3, CDC20, and MAD2 , 2001, The Journal of cell biology.
[27] Kim Nasmyth,et al. Genes involved in sister chromatid separation are needed for b-type cyclin proteolysis in budding yeast , 1995, Cell.
[28] K. Nasmyth,et al. The anaphase-promoting complex is required in G1 arrested yeast cells to inhibit B-type cyclin accumulation and to prevent uncontrolled entry into S-phase. , 1997, Journal of cell science.
[29] Hongtao Yu,et al. The Mad2 spindle checkpoint protein undergoes similar major conformational changes upon binding to either Mad1 or Cdc20. , 2002, Molecular cell.
[30] R. Deshaies. SCF and Cullin/Ring H2-based ubiquitin ligases. , 1999, Annual review of cell and developmental biology.
[31] J. Peters,et al. Subunits and substrates of the anaphase-promoting complex. , 1999, Experimental cell research.
[32] A. Hershko,et al. Reversible phosphorylation controls the activity of cyclosome-associated cyclin-ubiquitin ligase. , 1995, Proceedings of the National Academy of Sciences of the United States of America.
[33] Angelika Amon,et al. The regulation of Cdc20 proteolysis reveals a role for the APC components Cdc23 and Cdc27 during S phase and early mitosis , 1998, Current Biology.
[34] Jiri Bartek,et al. Accumulation of cyclin B1 requires E2F and cyclin-A-dependent rearrangement of the anaphase-promoting complex , 1999, Nature.
[35] Kim Nasmyth,et al. Closing the cell cycle circle in yeast: G2 cyclin proteolysis initiated at mitosis persists until the activation of G1 cyclins in the next cycle , 1994, Cell.
[36] A. Murray,et al. Cyclin is degraded by the ubiquitin pathway , 1991, Nature.
[37] M. Kirschner,et al. The KEN box: an APC recognition signal distinct from the D box targeted by Cdh1. , 2000, Genes & development.
[38] Tim Hunt,et al. Anaphase-Promoting Complex/Cyclosome–Dependent Proteolysis of Human Cyclin a Starts at the Beginning of Mitosis and Is Not Subject to the Spindle Assembly Checkpoint , 2001, The Journal of cell biology.
[39] C. Rieder,et al. Anaphase onset in vertebrate somatic cells is controlled by a checkpoint that monitors sister kinetochore attachment to the spindle , 1994, The Journal of cell biology.
[40] R. Nicklas,et al. Mitotic forces control a cell-cycle checkpoint , 1995, Nature.
[41] David O. Morgan,et al. Regulation of the APC and the exit from mitosis , 1999, Nature Cell Biology.
[42] P. Jackson,et al. Emi1 regulates the anaphase-promoting complex by a different mechanism than Mad2 proteins. , 2001, Genes & development.
[43] T. Maeda,et al. Human p55(CDC)/Cdc20 associates with cyclin A and is phosphorylated by the cyclin A-Cdk2 complex. , 2000, Biochemical and biophysical research communications.
[44] Andrew W. Murray,et al. Anaphase is initiated by proteolysis rather than by the inactivation of maturation-promoting factor , 1993, Cell.
[45] A. Amon,et al. A Mechanism for Coupling Exit from Mitosis to Partitioning of the Nucleus , 2000, Cell.
[46] K. Kitamura,et al. Fission yeast Ste9, a homolog of Hct1/Cdh1 and Fizzy-related, is a novel negative regulator of cell cycle progression during G1-phase. , 1998, Molecular biology of the cell.
[47] A. Hershko,et al. Methylated ubiquitin inhibits cyclin degradation in clam embryo extracts. , 1991, The Journal of biological chemistry.
[48] S. Elledge,et al. Structure of the Cul1–Rbx1–Skp1–F boxSkp2 SCF ubiquitin ligase complex , 2002, Nature.
[49] A. Murray,et al. Budding yeast Cdc20: a target of the spindle checkpoint. , 1998, Science.
[50] J. Diffley,et al. CDK inactivation is the only essential function of the APC/C and the mitotic exit network proteins for origin resetting during mitosis. , 2000, Molecular cell.
[51] Michael R. Speicher,et al. Securin Is Required for Chromosomal Stability in Human Cells , 2001, Cell.
[52] C. Lehner,et al. Drosophila fizzy-related Down-Regulates Mitotic Cyclins and Is Required for Cell Proliferation Arrest and Entry into Endocycles , 1997, Cell.
[53] Alexandre V. Podtelejnikov,et al. Characterization of the DOC1/APC10 Subunit of the Yeast and the Human Anaphase-promoting Complex* , 1999, The Journal of Biological Chemistry.
[54] M. Brandeis,et al. Cdk1 is essential for mammalian cyclosome/APC regulation. , 2000, Experimental cell research.
[55] J. Peters,et al. Two Distinct Pathways Remove Mammalian Cohesin from Chromosome Arms in Prophase and from Centromeres in Anaphase , 2000, Cell.
[56] M. Mann,et al. Mitotic regulation of the APC activator proteins CDC20 and CDH1. , 2000, Molecular biology of the cell.
[57] M. Kirschner,et al. Inhibition of Cdh1-APC by the MAD2-related protein MAD2L2: a novel mechanism for regulating Cdh1. , 2001, Genes & development.
[58] Kim Nasmyth,et al. An ESP1/PDS1 Complex Regulates Loss of Sister Chromatid Cohesion at the Metaphase to Anaphase Transition in Yeast , 1998, Cell.
[59] M. Kitagawa,et al. Cell cycle-dependent expression of mammalian E2-C regulated by the anaphase-promoting complex/cyclosome. , 2000, Molecular biology of the cell.
[60] K Nasmyth,et al. Mass spectrometric analysis of the anaphase-promoting complex from yeast: identification of a subunit related to cullins. , 1998, Science.
[61] Y. Protopopov,et al. Phosphorylation of the cyclosome is required for its stimulation by Fizzy/cdc20. , 1999, Biochemical and biophysical research communications.
[62] J. Peters,et al. Expression of the CDH1-associated form of the anaphase-promoting complex in postmitotic neurons. , 1999, Proceedings of the National Academy of Sciences of the United States of America.
[63] A. Murray,et al. The Xenopus Chromokinesin Xkid Is Essential for Metaphase Chromosome Alignment and Must Be Degraded to Allow Anaphase Chromosome Movement , 2000, Cell.
[64] M. Kirschner,et al. Identification of a novel ubiquitin-conjugating enzyme involved in mitotic cyclin degradation , 1996, Current Biology.
[65] K. Nasmyth,et al. Whose end is destruction: cell division and the anaphase-promoting complex. , 1999, Genes & development.
[66] Kim Nasmyth,et al. Cleavage of Cohesin by the CD Clan Protease Separin Triggers Anaphase in Yeast , 2000, Cell.
[67] Anna Shevchenko,et al. Exit from Mitosis Is Triggered by Tem1-Dependent Release of the Protein Phosphatase Cdc14 from Nucleolar RENT Complex , 1999, Cell.
[68] M. Solomon,et al. D box and KEN box motifs in budding yeast Hsl1p are required for APC-mediated degradation and direct binding to Cdc20p and Cdh1p. , 2001, Genes & development.
[69] A. Amon,et al. MEN and SIN: what's the difference? , 2001, Nature Reviews Molecular Cell Biology.
[70] A. Fry,et al. APC/C‐mediated destruction of the centrosomal kinase Nek2A occurs in early mitosis and depends upon a cyclin A‐type D‐box , 2001, The EMBO journal.
[71] Stuart Tugendreich,et al. CDC27Hs colocalizes with CDC16Hs to the centrosome and mitotic spindle and is essential for the metaphase to anaphase transition , 1995, Cell.
[72] David Pellman,et al. Activity of the APCCdh1 form of the anaphase-promoting complex persists until S phase and prevents the premature expression of Cdc20p , 2001, The Journal of cell biology.
[73] J Deisenhofer,et al. APC2 Cullin protein and APC11 RING protein comprise the minimal ubiquitin ligase module of the anaphase-promoting complex. , 2001, Molecular biology of the cell.
[74] D. Barford,et al. Implications for the ubiquitination reaction of the anaphase-promoting complex from the crystal structure of the Doc1/Apc10 subunit. , 2002, Journal of molecular biology.
[75] I. Sumara,et al. The dissociation of cohesin from chromosomes in prophase is regulated by Polo-like kinase. , 2002, Molecular cell.
[76] T. Hirano,et al. Identification of Xenopus SMC protein complexes required for sister chromatid cohesion. , 1998, Genes & development.
[77] T. Toda,et al. Apc10 and Ste9/Srw1, two regulators of the APC–cyclosome, as well as the CDK inhibitor Rum1 are required for G1 cell‐cycle arrest in fission yeast , 1998, The EMBO journal.
[78] Andrew W. Murray,et al. Association of Spindle Assembly Checkpoint Component XMAD2 with Unattached Kinetochores , 1996, Science.
[79] D. Roof,et al. Degradation of the kinesin Kip1p at anaphase onset is mediated by the anaphase-promoting complex and Cdc20p , 2001, Proceedings of the National Academy of Sciences of the United States of America.
[80] Michael Schwab,et al. Yeast Hct1 Is a Regulator of Clb2 Cyclin Proteolysis , 1997, Cell.
[81] R. Benezra,et al. Mad2 transiently associates with an APC/p55Cdc complex during mitosis. , 1998, Proceedings of the National Academy of Sciences of the United States of America.
[82] M. Nakao,et al. Activation of Cdh1‐dependent APC is required for G1 cell cycle arrest and DNA damage‐induced G2 checkpoint in vertebrate cells , 2001, The EMBO journal.
[83] P. Nurse,et al. Fission yeast Fizzy‐related protein srw1p is a G1‐specific promoter of mitotic cyclin B degradation , 2000, The EMBO journal.
[84] Hongtao Yu,et al. Regulation of the Anaphase-promoting Complex by the Dual Specificity Phosphatase Human Cdc14a* , 2001, The Journal of Biological Chemistry.
[85] T. Hunt,et al. The proteolysis of mitotic cyclins in mammalian cells persists from the end of mitosis until the onset of S phase. , 1996, The EMBO journal.
[86] T. Toda,et al. Fission yeast TPR-family protein nuc2 is required for G1-arrest upon nitrogen starvation and is an inhibitor of septum formation. , 1995, Journal of cell science.
[87] Hongtao Yu,et al. Mad2-Independent inhibition of APCCdc20 by the mitotic checkpoint protein BubR1. , 2001, Developmental cell.
[88] S. Moreno,et al. APCste9/srw1 promotes degradation of mitotic cyclins in G1 and is inhibited by cdc2 phosphorylation , 2000, The EMBO journal.
[89] A. Murray,et al. Localization of Mad2 to Kinetochores Depends on Microtubule Attachment, Not Tension , 1998, The Journal of cell biology.
[90] Eric T. Rosenthal,et al. Cyclin: A protein specified by maternal mRNA in sea urchin eggs that is destroyed at each cleavage division , 1983, Cell.
[91] G. Braus,et al. Two different modes of cyclin Clb2 proteolysis during mitosis in Saccharomyces cerevisiae , 2000, FEBS letters.
[92] K Nasmyth,et al. Control of cyclin ubiquitination by CDK-regulated binding of Hct1 to the anaphase promoting complex. , 1998, Science.
[93] F. M. Yeong,et al. Exit from mitosis in budding yeast: biphasic inactivation of the Cdc28-Clb2 mitotic kinase and the role of Cdc20. , 2000, Molecular cell.
[94] M. Kirschner,et al. Direct binding of CDC20 protein family members activates the anaphase-promoting complex in mitosis and G1. , 1998, Molecular cell.
[95] P. Hieter,et al. The APC11 RING-H2 finger mediates E2-dependent ubiquitination. , 2000, Molecular biology of the cell.
[96] V. Guacci,et al. Pds1p, an inhibitor of anaphase in budding yeast, plays a critical role in the APC and checkpoint pathway(s) , 1996, The Journal of cell biology.
[97] M. Kirschner,et al. The anaphase-promoting complex mediates TGF-beta signaling by targeting SnoN for destruction. , 2001, Molecular cell.
[98] T. T. Su. Cell cycle: How, when and why cells get rid of cyclin A , 2001, Current Biology.
[99] J. Pines,et al. Temporal and spatial control of cyclin B1 destruction in metaphase , 1999, Nature Cell Biology.
[100] S. Gygi,et al. Dual Inhibition of Sister Chromatid Separation at Metaphase , 2001, Cell.
[101] A. Murray,et al. Lack of tension at kinetochores activates the spindle checkpoint in budding yeast , 2001, Current Biology.
[102] S. Zipursky,et al. Control of G1 in the developing Drosophila eye: rca1 regulates Cyclin A. , 1997, Genes & development.
[103] J. Peters,et al. Cohesin Cleavage by Separase Required for Anaphase and Cytokinesis in Human Cells , 2001, Science.
[104] W. Seufert,et al. Yeast Hct1 recognizes the mitotic cyclin Clb2 and other substrates of the ubiquitin ligase APC , 2001, The EMBO journal.
[105] J. Peters,et al. Emi1 Is a Mitotic Regulator that Interacts with Cdc20 and Inhibits the Anaphase Promoting Complex , 2001, Cell.
[106] A. Hershko,et al. The cyclosome, a large complex containing cyclin-selective ubiquitin ligase activity, targets cyclins for destruction at the end of mitosis. , 1995, Molecular biology of the cell.
[107] David O. Morgan,et al. Inhibitory phosphorylation of the APC regulator Hct1 is controlled by the kinase Cdc28 and the phosphatase Cdc14 , 1999, Current Biology.
[108] J. Massagué,et al. TGFβ Signaling in Growth Control, Cancer, and Heritable Disorders , 2000, Cell.
[109] C. Lehner,et al. Fizzy is required for activation of the APC/cyclosome in Xenopus egg extracts , 1998, The EMBO journal.
[110] J. Pines,et al. Cyclin a Is Destroyed in Prometaphase and Can Delay Chromosome Alignment and Anaphase , 2001, The Journal of cell biology.
[111] S. Fang,et al. RING fingers mediate ubiquitin-conjugating enzyme (E2)-dependent ubiquitination. , 1999, Proceedings of the National Academy of Sciences of the United States of America.
[112] M. Kirschner,et al. Identification of BIME as a Subunit of the Anaphase-Promoting Complex , 1996, Science.
[113] M. Tyers,et al. The phosphatase Cdc14 triggers mitotic exit by reversal of Cdk-dependent phosphorylation. , 1998, Molecular cell.
[114] M. Kirschner,et al. Substrate recognition by the Cdc20 and Cdh1 components of the anaphase-promoting complex. , 2001, Genes & development.
[115] R. Huber,et al. Crystal structure of the APC10/DOC1 subunit of the human anaphase-promoting complex , 2001, Nature Structural Biology.
[116] C. Lehner,et al. Exit from mitosis is regulated by Drosophila fizzy and the sequential destruction of cyclins A, B and B3. , 1995, The EMBO journal.
[117] F. Sprenger,et al. Rca1 inhibits APC-Cdh1(Fzr) and is required to prevent cyclin degradation in G2. , 2002, Developmental cell.
[118] K. Nasmyth. THE GENOME : Joining , Resolving , and Separating Sister Chromatids During Mitosis and Meiosis , 2006 .