The cellular mechanism of Aire control of T cell tolerance.
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[1] Yi-Tao Yu,et al. Incorporation of 5-fluorouracil into U2 snRNA blocks pseudouridylation and pre-mRNA splicing in vivo , 2006, Nucleic acids research.
[2] C. Benoist,et al. Chromosomal clustering of genes controlled by the aire transcription factor. , 2005, Proceedings of the National Academy of Sciences of the United States of America.
[3] B. Simon,et al. NMR Structure of the First PHD Finger of Autoimmune Regulator Protein (AIRE1) , 2005, Journal of Biological Chemistry.
[4] J. Drijfhout,et al. Cross-presentation by intercellular peptide transfer through gap junctions , 2005, Nature.
[5] A. Rudensky,et al. Regulatory T cell lineage specification by the forkhead transcription factor foxp3. , 2005, Immunity.
[6] T. Nomura,et al. Development of Autoimmunity against Transcriptionally Unrepressed Target Antigen in the Thymus of Aire-Deficient Mice1 , 2005, The Journal of Immunology.
[7] C. Benoist,et al. Number of T Reg Cells That Differentiate Does Not Increase upon Encounter of Agonist Ligand on Thymic Epithelial Cells , 2004, The Journal of experimental medicine.
[8] Michael J. Bevan,et al. Central Tolerance to Tissue-specific Antigens Mediated by Direct and Indirect Antigen Presentation , 2004, The Journal of experimental medicine.
[9] L. Peltonen,et al. Gene Dosage–limiting Role of Aire in Thymic Expression, Clonal Deletion, and Organ-specific Autoimmunity , 2004, The Journal of experimental medicine.
[10] K. Paulsson,et al. Evolutionary and functional perspectives of the major histocompatibility complex class I antigen-processing machinery , 2004, Cellular and Molecular Life Sciences CMLS.
[11] C. Benoist,et al. Back to central tolerance. , 2004, Immunity.
[12] N. Killeen,et al. CCR7 Directs the Migration of Thymocytes into the Thymic Medulla1 , 2004, The Journal of Immunology.
[13] S. Sakaguchi. Naturally arising CD4+ regulatory t cells for immunologic self-tolerance and negative control of immune responses. , 2004, Annual review of immunology.
[14] N. Shimizu,et al. AIRE Functions As an E3 Ubiquitin Ligase , 2004, The Journal of experimental medicine.
[15] P. Ohashi,et al. Negative selection and autoimmunity. , 2003, Current opinion in immunology.
[16] A. Rudensky,et al. Foxp3 programs the development and function of CD4+CD25+ regulatory T cells , 2003, Nature Immunology.
[17] Brigitta Stockinger,et al. T Cell Regulation as a Side Effect of Homeostasis and Competition , 2003, The Journal of experimental medicine.
[18] Mark S. Anderson,et al. Projection of an Immunological Self Shadow Within the Thymus by the Aire Protein , 2002, Science.
[19] L. Klein,et al. Promiscuous gene expression and central T-cell tolerance: more than meets the eye. , 2002, Trends in immunology.
[20] A. Arnold,et al. Sex differences in sex chromosome gene expression in mouse brain. , 2002, Human molecular genetics.
[21] L. Peltonen,et al. Aire deficient mice develop multiple features of APECED phenotype and show altered immune response. , 2002, Human molecular genetics.
[22] F. Momburg,et al. HLA-DM, HLA-DO and tapasin: functional similarities and differences. , 2002, Current opinion in immunology.
[23] L. Klein,et al. Promiscuous gene expression in medullary thymic epithelial cells mirrors the peripheral self , 2001, Nature Immunology.
[24] A. Naji,et al. Thymic selection of CD4+CD25+ regulatory T cells induced by an agonist self-peptide , 2001, Nature Immunology.
[25] S. Sakaguchi. Policing the regulators , 2001, Nature Immunology.
[26] A. Winoto,et al. The TNF Receptor Family Member CD30 Is Not Essential for Negative Selection1 , 2000, The Journal of Immunology.
[27] L. Klein,et al. CD4 T Cell Tolerance to Human C-reactive Protein, an Inducible Serum Protein, Is Mediated by Medullary Thymic Epithelium , 1998, The Journal of experimental medicine.
[28] C. Bishop,et al. Long-term T cell memory requires the surface expression of self-peptide/major histocompatibility complex molecules. , 1998, Proceedings of the National Academy of Sciences of the United States of America.
[29] A. Fisher,et al. How Many Thymocytes Audition for Selection? , 1997, The Journal of experimental medicine.
[30] Kathleen M. Smith,et al. Pancreatic gene expression in rare cells of thymic medulla: evidence for functional contribution to T cell tolerance. , 1997, International immunology.
[31] C. Benoist,et al. Targeted complementation of MHC class II deficiency by intrathymic delivery of recombinant adenoviruses. , 1997, Immunity.
[32] J. Miller,et al. Constitutive class I-restricted exogenous presentation of self antigens in vivo , 1996, The Journal of experimental medicine.
[33] M. Toda,et al. Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor alpha-chains (CD25). Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases. , 1995, Journal of immunology.
[34] A. Coutinho,et al. Lymphocytes selected in allogeneic thymic epithelium mediate dominant tolerance toward tissue grafts of the thymic epithelium haplotype. , 1995, Proceedings of the National Academy of Sciences of the United States of America.
[35] S. Rodda,et al. Peptide antagonists that promote positive selection are inefficient at T cell activation and thymocyte deletion , 1994, European journal of immunology.
[36] D. Hanahan,et al. T-cell tolerance toward a transgenic beta-cell antigen and transcription of endogenous pancreatic genes in thymus. , 1994, Proceedings of the National Academy of Sciences of the United States of America.
[37] T. Wilson,et al. The thymic microenvironment. , 1993, Immunology today.
[38] Polly Matzinger,et al. Does T-cell tolerance require a dedicated antigen-presenting cell? , 1989, Nature.
[39] H. Boehmer,et al. Positive selection of antigen-specific T cells in thymus by restricting MHC molecules , 1988, Nature.
[40] H. Boehmer,et al. Tolerance in T-cell-receptor transgenic mice involves deletion of nonmature CD4+8+ thymocytes , 1988, Nature.
[41] N. Shimizu,et al. AIRE Functions As an E 3 Ubiquitin Ligase , 2004 .
[42] A. Rudensky,et al. Foxp 3 programs the development and function of CD 4 + CD 25 + regulatory T cells , 2003 .
[43] L. Peltonen,et al. Aire regulates negative selection of organ-specific T cells , 2003, Nature Immunology.
[44] E. Schmitt,et al. The Regulatory T Cell Family: Distinct Subsets and their Interrelations , 2003 .
[45] A. Abbas,et al. The enemy within: keeping self-reactive T cells at bay in the periphery , 2002, Nature Reviews Immunology.
[46] Ray H. Baughman,et al. Supporting Online Material , 2003 .