Automatic Segmentation of the Pelvic Bones from CT Data Based on a Statistical Shape Model

We present an algorithm for automatic segmentation of the human pelvic bones from CT datasets that is based on the application of a statistical shape model. The proposed method is divided into three steps: 1) The averaged shape of the pelvis model is initially placed within the CT data using the Generalized Hough Transform, 2) the statistical shape model is then adapted to the image data by a transformation and variation of its shape modes, and 3) a final free-form deformation step based on optimal graph searching is applied to overcome the restrictive character of the statistical shape representation. We thoroughly evaluated the method on 50 manually segmented CT datasets by performing a leave-one-out study. The Generalized Hough Transform proved to be a reliable method for an automatic initial placement of the shape model within the CT data. Compared to the manual gold standard segmentations, our automatic segmentation approach produced an average surface distance of 1.2 ± 0.3mm after the adaptation of the statistical shape model, which could be reduced to 0.7±0.3mm using a final free-form deformation step. Together with an average segmentation time of less than 5 minutes, the results of our study indicate that our method meets the requirements of clinical routine.

[1]  Vladimir Kolmogorov,et al.  An experimental comparison of min-cut/max- flow algorithms for energy minimization in vision , 2001, IEEE Transactions on Pattern Analysis and Machine Intelligence.

[2]  B Haas,et al.  Automatic segmentation of thoracic and pelvic CT images for radiotherapy planning using implicit anatomic knowledge and organ-specific segmentation strategies , 2008, Physics in medicine and biology.

[3]  B. Ginneken,et al.  3D Segmentation in the Clinic: A Grand Challenge , 2007 .

[4]  Kourosh Khoshelham,et al.  Extending generalized hough transform to detect 3D objects in laser range data , 2007 .

[5]  W A Kalender,et al.  Technical advances in multi-slice spiral CT. , 2000, European journal of radiology.

[6]  Vladimir Kolmogorov,et al.  An Experimental Comparison of Min-Cut/Max-Flow Algorithms for Energy Minimization in Vision , 2004, IEEE Trans. Pattern Anal. Mach. Intell..

[7]  H Handels,et al.  Atlas-based Recognition of Anatomical Structures and Landmarks and the Automatic Computation of Orthopedic Parameters , 2004, Methods of Information in Medicine.

[8]  Russell H. Taylor,et al.  Statistical Atlases of Bone Anatomy: Construction, Iterative Improvement and Validation , 2007, MICCAI.

[9]  Hans-Christian Hege,et al.  Coupling Deformable Models for Multi-object Segmentation , 2008, ISBMS.

[10]  Hans-Christian Hege,et al.  A 3D statistical shape model of the pelvic bone for segmentation , 2004, SPIE Medical Imaging.

[11]  Hans Knutsson,et al.  Automatic Hip Bone Segmentation Using Non-Rigid Registration , 2006, 18th International Conference on Pattern Recognition (ICPR'06).

[12]  Hans-Christian Hege,et al.  3D Reconstruction of Individual Anatomy from Medical Image Data: Segmentation and Geometry Processing , 2007 .

[13]  Xiaodong Wu,et al.  Optimal Surface Segmentation in Volumetric Images-A Graph-Theoretic Approach , 2006, IEEE Transactions on Pattern Analysis and Machine Intelligence.

[14]  Vladimir Pekar,et al.  Automated model-based organ delineation for radiotherapy planning in prostatic region. , 2004, International journal of radiation oncology, biology, physics.

[15]  Dana H. Ballard,et al.  Generalizing the Hough transform to detect arbitrary shapes , 1981, Pattern Recognit..