Development of bacterial cellulose based slow-release active films by incorporation of Scrophularia striata Boiss. extract.

Novel bacterial cellulose (BC) based monolayer and multilayer films, incorporating 5wt.% Scrophularia striata Boiss. extract (SE) were obtained. The effect of lamination and β-cyclodextrin (β-CD) inclusion complexation of SE on morphological, physical, antioxidant and release properties of films were investigated. FT-IR results reflected that some new interactions have occurred between BC and β-CD. The XRD analyses showed a decrease in diffraction intensities of BC by addition of free SE. SEM results indicated that the intrinsic compactness of the BC film was preserved by addition of SE/β-CD complex. Lamination and SE/β-CD addition enhanced the mechanical properties. SE loaded films exhibited a good antioxidant activity. Release studies indicated that the release rate and diffusion coefficient (D) of SE in 95% ethanol simulant were significantly decreased by lamination and complexation of SE with β-CD. Results suggest that SE loaded BC films may be used as controlled release antioxidant food active packaging.

[1]  R. Gavara,et al.  Preparation and characterization of chitosan/HP-β-cyclodextrins composites with high sorption capacity for carvacrol. , 2013, Carbohydrate polymers.

[2]  J. Marcy,et al.  Formation of natamycin:cyclodextrin inclusion complexes and their characterization. , 2003, Journal of agricultural and food chemistry.

[3]  M. Mahboubi,et al.  Total Phenolic, Total Flavonoids, Antioxidant and Antimicrobial Activities of Scrophularia Striata Boiss Extracts , 2013, Jundishapur journal of natural pharmaceutical products.

[4]  R. Auras,et al.  Release of α-Tocopherol from Poly(lactic acid) films, and its effect on the oxidative stability of soybean oil , 2011 .

[5]  K. Paknikar,et al.  Applications of bacterial cellulose and its composites in biomedicine , 2015, Applied Microbiology and Biotechnology.

[6]  Siyao Sui,et al.  Antimicrobial and mechanical properties of β-cyclodextrin inclusion with essential oils in chitosan films. , 2014, Journal of agricultural and food chemistry.

[7]  Rob Veraart.  Compliance Testing, Declaration of Compliance, and Supporting Documentation in the EU , 2010 .

[8]  J. Marcy,et al.  Controlled release of α-tocopherol, quercetin, and their cyclodextrin inclusion complexes from linear low-density polyethylene (LLDPE) films into a coconut oil model food system , 2010, Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment.

[9]  Baoguo Sun,et al.  Physicochemical and release characterisation of garlic oil-β-cyclodextrin inclusion complexes , 2011 .

[10]  Y. Wan,et al.  Introduction of broad spectrum antibacterial properties to bacterial cellulose nanofibers via immobilising ε-polylysine nanocoatings , 2014 .

[11]  S. Desobry,et al.  Release of synthetic phenolic antioxidants from extruded poly lactic acid (PLA) film , 2012 .

[12]  F. Jalilian,et al.  Antibacterial effects of Scrophularia striata seed aqueous extract on staphilococcus aureus , 2013 .

[13]  H. Almasi,et al.  Morphological, physical, antimicrobial and release properties of ZnO nanoparticles-loaded bacterial cellulose films. , 2016, Carbohydrate polymers.

[14]  Feng F. Hong,et al.  Preparation and evaluation of a kind of bacterial cellulose dry films with antibacterial properties , 2011 .

[15]  R. Auras,et al.  Release of butylated hydroxytoluene (BHT) from Poly(lactic acid) films , 2011 .

[16]  M. Khorramizadeh,et al.  Flavonoids, cinnamic acid and phenyl propanoid from aerial parts of Scrophularia striata , 2010, Pharmaceutical biology.

[17]  P. Schmidt,et al.  Phase solubility studies of pure (−)-α-bisabolol and camomile essential oil with β-cyclodextrin , 2003 .

[18]  Huaping Wang,et al.  Functionalized bacterial cellulose derivatives and nanocomposites. , 2014, Carbohydrate polymers.

[19]  Weili Zheng,et al.  Synthesis of flexible magnetic nanohybrid based on bacterial cellulose under ultrasonic irradiation. , 2013, Materials science & engineering. C, Materials for biological applications.

[20]  Rajeswari Challa,et al.  Cyclodextrins in drug delivery: An updated review , 2005, AAPS PharmSciTech.

[21]  Yudong Zheng,et al.  In situ synthesis of silver-nanoparticles/bacterial cellulose composites for slow-released antimicrobial wound dressing. , 2014, Carbohydrate polymers.

[22]  F. Domingues,et al.  Characterization and antimicrobial activity of cellulose derivatives films incorporated with a resveratrol inclusion complex , 2016 .

[23]  Kaili Song,et al.  Preparation of multi-functional cellulose containing huge conjugated system and its UV-protective and antibacterial property. , 2014, Carbohydrate polymers.

[24]  R. Gavara,et al.  Antimicrobial packaging of chicken fillets based on the release of carvacrol from chitosan/cyclodextrin films. , 2014, International journal of food microbiology.

[25]  H. Almasi,et al.  Chitosan films incorporated with nettle (Urtica dioica L.) extract-loaded nanoliposomes: I. Physicochemical characterisation and antimicrobial properties , 2016, Journal of microencapsulation.

[26]  Hong Liu,et al.  Preparation of cellulose fiber–TiO2 nanobelt–silver nanoparticle hierarchically structured hybrid paper and its photocatalytic and antibacterial properties , 2013 .

[27]  A. Afshari,et al.  Suppression of nitric oxide production in activated murine peritoneal macrophages in vitro and ex vivo by Scrophularia striata ethanolic extract. , 2009 .

[28]  T. Dobre,et al.  Ultrasound influence upon calcium carbonate precipitation on bacterial cellulose membranes. , 2012, Ultrasonics sonochemistry.

[29]  Younes Messaddeq,et al.  Self-supported silver nanoparticles containing bacterial cellulose membranes , 2008 .

[30]  N. A. Rahman,et al.  Overview of Bacterial Cellulose Production and Application , 2014 .

[31]  Mazhar Ul-Islam,et al.  Overview of bacterial cellulose composites: a multipurpose advanced material. , 2013, Carbohydrate polymers.

[32]  M. Gidley,et al.  Potential of a nisin-containing bacterial cellulose film to inhibit Listeria monocytogenes on processed meats. , 2008, Food microbiology.

[33]  A. Stoica-Guzun,et al.  Controlled release of sorbic acid from bacterial cellulose based mono and multilayer antimicrobial films , 2012 .

[34]  Ericka Ford,et al.  X-ray Diffraction of Cotton Treated with Neutralized Vegetable Oil-based Macromolecular Crosslinkers , 2010 .

[35]  H. Almasi,et al.  Chitosan films incorporated with nettle (Urtica Dioica L.) extract-loaded nanoliposomes: II. Antioxidant activity and release properties , 2016, Journal of microencapsulation.

[36]  H. Almasi,et al.  Development of a novel controlled-release nanocomposite based on poly(lactic acid) to increase the oxidative stability of soybean oil , 2014, Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment.

[37]  M. Azadbakht,et al.  Antioxidant and Neuroprotective Effects of Scrophularia striata Extract Against Oxidative Stress-Induced Neurotoxicity , 2013, Cellular and Molecular Neurobiology.

[38]  H. Almasi,et al.  Heterogeneous modification of softwoods cellulose nanofibers with oleic acid: Effect of reaction time and oleic acid concentration , 2015, Fibers and Polymers.

[39]  B. Liu,et al.  Cellulose sulfate based film with slow-release antimicrobial properties prepared by incorporation of mustard essential oil and β-cyclodextrin , 2016 .

[40]  John Crank,et al.  The Mathematics Of Diffusion , 1956 .

[41]  A. Stoica-Guzun,et al.  Vanillin release from poly(vinyl alcohol)-bacterial cellulose mono and multilayer films , 2013 .

[42]  A. Chiralt,et al.  Influence of nanoliposomes incorporation on properties of film forming dispersions and films based on corn starch and sodium caseinate , 2014 .

[43]  S. Ostad,et al.  Neuroprotective Effect of Total and Sequential Extract of Scrophularia striata Boiss. in Rat Cerebellar Granule Neurons Following Glutamate- Induced Neurotoxicity: An In-vitro Study , 2013, Iranian journal of pharmaceutical research : IJPR.

[44]  Yue Zhang,et al.  Utilization of bacterial cellulose in food , 2014 .

[45]  E. Peralta,et al.  Migration of α-tocopherol from LDPE films to corn oil and its effect on the oxidative stability , 2010 .