C8-substituted pyrido[3,4-d]pyrimidin-4(3H)-ones: Studies towards the identification of potent, cell penetrant Jumonji C domain containing histone lysine demethylase 4 subfamily (KDM4) inhibitors, compound profiling in cell-based target engagement assays
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G. F. Ruda | O. Fedorov | O. Rossanese | R. V. van Montfort | Y. Le Bihan | P. Brennan | F. Raynaud | A. Hayes | A. Tumber | R. Lanigan | J. Blagg | C. McAndrew | J. Bennett | B. Atrash | F. Jeganathan | K. England | V. Bavetsias | R. Burke | Harry Saville | Erald Shehu | S. Velupillai | M. G. McLaughlin | N. Mok | Adam Donovan | F. Wood | Paul Eve | L. Carmichael | Kathy Tomlin | Andrew G Malcolm | Andrew G. Malcolm