Invasive pulmonary aspergillosis in an immunocompetent infant associated with short term steroid Đmmunkompetan bir infantta kisa süreli steroid tedavisi ile ilikili invaziv pulmoner aspergilloz

Summary Invasive aspergillosis occurs very rarely in immunocompetent hosts. We report a case of invasive fungal infection in an infant who was treated with short term of inhaled and systemic steroids although there was no detectable immune deficiency. This case was presented in order to demonstrate the potential risk for opportunistic fungal infections in children treated with short term systemic and inhaled corticosteroids.

[1]  A. Zaas,et al.  Plasminogen Alleles Influence Susceptibility to Invasive Aspergillosis , 2008, PLoS genetics.

[2]  J. Mainardi,et al.  Fulminant invasive pulmonary aspergillosis in immunocompetent patients--a two-case report. , 2003, Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases.

[3]  L. Wheat.  Rapid diagnosis of invasive aspergillosis by antigen detection , 2003, Transplant infectious disease : an official journal of the Transplantation Society.

[4]  C. Maslo,et al.  Epidemiology of invasive aspergillosis in France: a six-year multicentric survey in the Greater Paris area. , 2002, The Journal of hospital infection.

[5]  Sonia Vázquez,et al.  Probable aspergilosis pulmonar invasora y tratamiento con esteroides inhalados , 2002 .

[6]  D. Denning,et al.  Practice Guidelines for Diseases Caused by Aspergillus , 2000 .

[7]  J. Rello,et al.  Invasive pulmonary aspergillosis in patients with chronic obstructive pulmonary disease: report of eight cases and review. , 1998, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

[8]  J. Aucott.  Glucocorticoids and infection. , 1994, Endocrinology and metabolism clinics of North America.

[9]  D. Venzon,et al.  Prevention of corticosteroid-induced suppression of human polymorphonuclear leukocyte-induced damage of Aspergillus fumigatus hyphae by granulocyte colony-stimulating factor and gamma interferon , 1993, Infection and immunity.

[10]  M. J. Schiff,et al.  Corticosteroid treatment as a risk factor for invasive aspergillosis in patients with lung disease. , 1991, Thorax.

[11]  F. Griffin,et al.  Invasive pulmonary aspergillosis in nonimmunocompromised, nonneutropenic hosts. , 1986, Reviews of infectious diseases.

[12]  R. S. Gordon,et al.  Incidence of infection in systemic lupus erythematosus. , 1974, Arthritis and rheumatism.