Using the split plot and multi-quadric regressive orthogonal cross-course rotary combination design, corn variety Denghai 6's yield and yield components, important colony quality and physiological index, microclimate index in field and technical planting for high yield were studied. Cultivation for high yield showed that Denghai 6 had the great potential of increase yield. The average yield of two years was 12510kg/ha for 13.85ha, the highest grain yield (754.7m2) was 15477kg/ha. The climatic conditions can meet the needs for high yield during the whole growth stage of corn in the mountain area of Northwest Guizhou.