Isolation and Structure Elucidation of a New Diterpene Glycoside from Stevia rebaudiana Bertoni

A new minor diterpene glycoside has been isolated from a commercial extract of the leaves of Stevia rebaudiana and its structure was identified as 13-[(2- O -β-D-glucopyranosyl-β-D-glucopyranosyl)oxy] ent -kaur-16-en-19-oic acid-[2- O -(2- O -β-D-glucopyranosyl)-β-D-glucopyranosyl-3- O -b-D-glucopyranosyl-β-D-glucopyranosyl] ester ( 1 ) based on extensive NMR (1D and 2D) and mass spectroscopic data, and hydrolysis studies.

[1]  S. Meneni,et al.  Isolation and Structural Characterization of a New Minor Steviol Glycoside of Stevia rebaudiana , 2016 .

[2]  V. S. Chaturvedula.  Isolation and Structural Characterization of a New Minor Penta β-D-Glucopyranosyl Diterpene from Stevia rebaudiana Bertoni , 2014 .

[3]  V. S. Chaturvedula,et al.  Isolation and Structural Characterization of a New Minor Diterpene Glycoside from Stevia rebaudiana , 2014, Natural product communications.

[4]  A. Starratt,et al.  Rebaudioside F, a diterpene glycoside from Stevia rebaudiana. , 2002, Phytochemistry.

[5]  M. C. Hoang,et al.  Oleanane saponins from Polyscias fruticosa. , 1998, Phytochemistry.

[6]  V. S. Chaturvedula,et al.  Reversed-Phase HPLC Analysis of Steviol Glycosides Isolated from Stevia rebaudiana Bertoni , 2014 .

[7]  R. Kasai,et al.  New sweet diterpene glucosides from Stevia rebaudiana , 1976 .

[8]  I. Prakash,et al.  Isolation, Characterization and Sensory Evaluation of a Hexa β-D-Glucopyranosyl Diterpene from Stevia rebaudiana , 2013, Natural product communications.

[9]  A. Starratt,et al.  Stevia rebaudiana: Its agricultural, biological, and chemical properties , 1998 .

[10]  J. Miller,et al.  New cytotoxic oleanane saponins from the infructescences of Polyscias amplifolia from the Madagascar rainforest. , 2003, Planta medica.

[11]  R. Kasai,et al.  Minor diterpene glycosides from sweet leaves of Rubus suavissimus , 1992 .

[12]  L. Walker,et al.  A new dammarane-type triterpene glycoside from Polyscias fulva. , 2001, Journal of natural products.

[13]  E. Mosettig,et al.  STEVIOSIDE. II. THE STRUCTURE OF THE AGLUCON , 1955 .

[14]  Masaru Kobayashi,et al.  Dulcosides A and B, new diterpene glycosides from Stevia rebaudiana , 1977 .

[15]  T. Ueda,et al.  Facile discrimination of aldose enantiomers by reversed-phase HPLC. , 2007, Chemical & pharmaceutical bulletin.

[16]  S. Meneni,et al.  A New Penta β -D-Glucopyranosyl Diterpene from Stevia rebaudiana , 2017 .

[17]  E. Mosettig,et al.  The Absolute Configuration of Steviol and Isosteviol , 1963 .