Deficiency in coatomer complex I causes aberrant activation of STING signalling
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Laura F. Dagley | K. Rogers | G. Hartmann | Michael J. Mlodzianoski | M. Geyer | S. Masters | D. De Nardo | Sophia Davidson | M. Gantier | S. Volpi | M. Gattorno | I. Prigione | L. Dagley | Pawat Laohamonthonkul | C. Harapas | Katja Hrovat-Schaale | A. Steiner | Chien-Hsiung Yu | T. Zillinger | R. R. J. Low | P. Laohamonthonkul | K. Hrovat-Schaale | R. R. Low
[1] J. Orange,et al. Combined immunodeficiency due to a mutation in the γ1 subunit of the coat protein I complex. , 2021, The Journal of clinical investigation.
[2] Takehiro Suzuki,et al. Homeostatic regulation of STING by retrograde membrane traffic to the ER , 2021, Nature communications.
[3] Shunying Zhao,et al. Effective sirolimus treatment of two COPA syndrome patients. , 2020, The journal of allergy and clinical immunology. In practice.
[4] M. Frémond,et al. COPA syndrome, 5 years after: where are we? , 2020, Joint bone spine.
[5] T. Molina,et al. Mutations in COPA lead to abnormal trafficking of STING to the Golgi and interferon signaling , 2020, The Journal of experimental medicine.
[6] J. Enghild,et al. STEEP mediates STING ER exit and activation of signaling , 2020, Nature Immunology.
[7] J. Klumperman,et al. A paralog-specific role of COPI vesicles in the neuronal differentiation of mouse pluripotent cells , 2020, Life Science Alliance.
[8] H. Funabiki,et al. Regulation and Consequences of cGAS Activation by Self-DNA. , 2020, Trends in cell biology.
[9] Christopher S. Law,et al. A defect in COPI-mediated transport of STING causes immune dysregulation in COPA syndrome , 2020, bioRxiv.
[10] A. Smith,et al. TBK1 and IKKε Act Redundantly to Mediate STING-Induced NF-κB Responses in Myeloid Cells. , 2020, Cell reports.
[11] E. Lim,et al. SV40 Large T Antigen Is Not Responsible for the Loss of STING in 293T Cells but Can Inhibit cGAS-STING Interferon Induction , 2020, Viruses.
[12] S. K. Campos,et al. Attenuation of cGAS/STING activity during mitosis , 2019, Life Science Alliance.
[13] G. Horneff,et al. Baricitinib in therapy of COPA syndrome in a 15-year-old girl. , 2020, European journal of rheumatology.
[14] Anup D Shah,et al. LFQ-Analyst: An easy-to-use interactive web-platform to analyze and visualize label-free proteomics data preprocessed with MaxQuant. , 2020, Journal of proteome research.
[15] Y. Crow,et al. Use of ruxolitinib in COPA syndrome manifesting as life-threatening alveolar haemorrhage , 2019, Thorax.
[16] Yan-Yi Wang,et al. YIPF5 Is Essential for Innate Immunity to DNA Virus and Facilitates COPII-Dependent STING Trafficking , 2019, The Journal of Immunology.
[17] Zhijian J. Chen,et al. Autophagy Induction via STING Trafficking Is a Primordial Function of the cGAS Pathway , 2019, Nature.
[18] T. Weiss,et al. STING Polymer Structure Reveals Mechanisms for Activation, Hyperactivation, and Inhibition , 2019, Cell.
[19] F. Wieland,et al. Proteomic Profiling of Mammalian COPII and COPI Vesicles. , 2019, Cell reports.
[20] Martin Eisenacher,et al. The PRIDE database and related tools and resources in 2019: improving support for quantification data , 2018, Nucleic Acids Res..
[21] Ellen F. Macnamara,et al. Expanding the phenotype of COPA syndrome: a kindred with typical and atypical features , 2018, Journal of Medical Genetics.
[22] Laura F. Dagley,et al. Therapeutic blockade of activin-A improves NK cell function and antitumor immunity , 2019, Science Signaling.
[23] Zhengfan Jiang,et al. STING directly activates autophagy to tune the innate immune response , 2018, Cell Death & Differentiation.
[24] H. Shu,et al. TMED2 Potentiates Cellular IFN Responses to DNA Viruses by Reinforcing MITA Dimerization and Facilitating Its Trafficking. , 2018, Cell reports.
[25] Jian-hua Zhou,et al. Type III Interferons in Viral Infection and Antiviral Immunity , 2018, Cellular Physiology and Biochemistry.
[26] Kota Saito,et al. The binding of TBK1 to STING requires exocytic membrane traffic from the ER. , 2018, Biochemical and biophysical research communications.
[27] V. Rao,et al. Interleukin-1 receptor–associated kinase 4 (IRAK4) plays a dual role in myddosome formation and Toll-like receptor signaling , 2018, The Journal of Biological Chemistry.
[28] Zhijian J. Chen,et al. DNA-induced liquid phase condensation of cGAS activates innate immune signaling , 2018, Science.
[29] N. Hacohen,et al. The Chaperone UNC93B1 Regulates Toll‐like Receptor Stability Independently of Endosomal TLR Transport , 2018, Immunity.
[30] Zhijian J. Chen,et al. The cGAS–cGAMP–STING pathway connects DNA damage to inflammation, senescence, and cancer , 2018, The Journal of experimental medicine.
[31] S. Volpi,et al. Type I interferon pathway activation in COPA syndrome. , 2017, Clinical immunology.
[32] E. Latz,et al. Immortalization of Murine Bone Marrow-Derived Macrophages. , 2018, Methods in molecular biology.
[33] P. Baker,et al. Generation of Genetic Knockouts in Myeloid Cell Lines Using a Lentiviral CRISPR/Cas9 System. , 2018, Methods in molecular biology.
[34] Nan Yan,et al. Trafficking-Mediated STING Degradation Requires Sorting to Acidified Endolysosomes and Can Be Targeted to Enhance Anti-tumor Response. , 2017, Cell reports.
[35] Gudmundur A. Thorisson,et al. COPA syndrome in an Icelandic family caused by a recurrent missense mutation in COPA , 2017, BMC Medical Genetics.
[36] C. Verma,et al. A New Generation of Arachidonic Acid Analogues as Potential Neurological Agent Targeting Cytosolic Phospholipase A2 , 2017, Scientific Reports.
[37] K. Sund,et al. Copb2 is essential for embryogenesis and hypomorphic mutations cause human microcephaly , 2017, bioRxiv.
[38] F. Rieux-Laucat,et al. Disease‐associated mutations identify a novel region in human STING necessary for the control of type I interferon signaling , 2017, The Journal of allergy and clinical immunology.
[39] O. Nureki,et al. Cyclic GMP-AMP as an Endogenous Second Messenger in Innate Immune Signaling by Cytosolic DNA. , 2017, Annual review of biochemistry.
[40] E. Kiss-Toth,et al. Regulating STING in health and disease , 2017, Journal of Inflammation.
[41] Laura F. Dagley,et al. Suppressor of cytokine signaling (SOCS)5 ameliorates influenza infection via inhibition of EGFR signaling , 2017, eLife.
[42] Taoyong Chen,et al. The tyrosine kinase Src promotes phosphorylation of the kinase TBK1 to facilitate type I interferon production after viral infection , 2017, Science Signaling.
[43] Nan Yan,et al. Methods of Assessing STING Activation and Trafficking. , 2017, Methods in molecular biology.
[44] K. Shirahige,et al. ARCN1 Mutations Cause a Recognizable Craniofacial Syndrome Due to COPI-Mediated Transport Defects. , 2016, American journal of human genetics.
[45] Laura F. Dagley,et al. CIS is a potent checkpoint in NK cell–mediated tumor immunity , 2016, Nature Immunology.
[46] V. Hornung,et al. Cre-dependent DNA recombination activates a STING-dependent innate immune response , 2016, Nucleic acids research.
[47] Hariprakash Haragopal,et al. Intracellular zinc distribution in mitochondria, ER and the Golgi apparatus. , 2016, International journal of physiology, pathophysiology and pharmacology.
[48] R. Voituriez,et al. ESCRT III repairs nuclear envelope ruptures during cell migration to limit DNA damage and cell death , 2016, Science.
[49] Á. Simonyi,et al. Cytosolic phospholipase A2 plays a crucial role in ROS/NO signaling during microglial activation through the lipoxygenase pathway , 2015, Journal of Neuroinflammation.
[50] Elizabeth E Gray,et al. DNA tumor virus oncogenes antagonize the cGAS-STING DNA-sensing pathway , 2015, Science.
[51] Nan Yan,et al. STING Activation by Translocation from the ER Is Associated with Infection and Autoinflammatory Disease. , 2015, Cell host & microbe.
[52] Mark S. Anderson,et al. COPA mutations impair ER-Golgi transport and cause hereditary autoimmune-mediated lung disease and arthritis , 2015, Nature Genetics.
[53] N. Grishin,et al. Phosphorylation of innate immune adaptor proteins MAVS, STING, and TRIF induces IRF3 activation , 2015, Science.
[54] Stephen Wilcox,et al. An inducible lentiviral guide RNA platform enables the identification of tumor-essential genes and tumor-promoting mutations in vivo. , 2015, Cell reports.
[55] T. Taniguchi,et al. Apoptotic Caspases Prevent the Induction of Type I Interferons by Mitochondrial DNA , 2014, Cell.
[56] Matthew E. Ritchie,et al. Apoptotic Caspases Suppress mtDNA-Induced STING-Mediated Type I IFN Production , 2014, Cell.
[57] V. Hornung,et al. Cytosolic RNA:DNA hybrids activate the cGAS–STING axis , 2014, The EMBO journal.
[58] Ha Won Kim,et al. Activated STING in a vascular and pulmonary syndrome. , 2014, The New England journal of medicine.
[59] Neville E. Sanjana,et al. Improved vectors and genome-wide libraries for CRISPR screening , 2014, Nature Methods.
[60] Neville E. Sanjana,et al. Genome-Scale CRISPR-Cas9 Knockout Screening in Human Cells , 2014, Science.
[61] V. Hornung,et al. cGAS produces a 2′-5′-linked cyclic dinucleotide second messenger that activates STING , 2013, Nature.
[62] Y. Liu,et al. Transmembrane Protein 214 (TMEM214) Mediates Endoplasmic Reticulum Stress-induced Caspase 4 Enzyme Activation and Apoptosis* , 2013, The Journal of Biological Chemistry.
[63] Zhijian J. Chen,et al. Cyclic GMP-AMP Synthase Is a Cytosolic DNA Sensor That Activates the Type I Interferon Pathway , 2013, Science.
[64] Zhijian J. Chen,et al. STING Specifies IRF3 Phosphorylation by TBK1 in the Cytosolic DNA Signaling Pathway , 2012, Science Signaling.
[65] B. Rothermel,et al. Endoplasmic reticulum: ER stress regulates mitochondrial bioenergetics. , 2012, The international journal of biochemistry & cell biology.
[66] F. Wieland,et al. COPI budding within the Golgi stack. , 2011, Cold Spring Harbor perspectives in biology.
[67] E. Sztul,et al. COPII and COPI traffic at the ER-Golgi interface. , 2011, Physiology.
[68] R. Kaufman,et al. ER stress and its functional link to mitochondria: role in cell survival and death. , 2011, Cold Spring Harbor perspectives in biology.
[69] J. Rathmell,et al. ER stress modulates cellular metabolism. , 2011, The Biochemical journal.
[70] M. Mann,et al. Andromeda: a peptide search engine integrated into the MaxQuant environment. , 2011, Journal of proteome research.
[71] R. Kaufman,et al. ERStressandItsFunctionalLinktoMitochondria: Role in Cell Survival and Death , 2011 .
[72] Atsushi B. Tsuji,et al. Knockdown of COPA, identified by loss-of-function screen, induces apoptosis and suppresses tumor growth in mesothelioma mouse model. , 2010, Genomics.
[73] K. Ishii,et al. Atg9a controls dsDNA-driven dynamic translocation of STING and the innate immune response , 2009, Proceedings of the National Academy of Sciences.
[74] G. Barber,et al. STING regulates intracellular DNA-mediated, type I interferon-dependent innate immunity , 2009, Nature.
[75] R. Beck,et al. The COPI system: Molecular mechanisms and function , 2009, FEBS letters.
[76] C. Leslie,et al. Group IV Phospholipase A2α Controls the Formation of Inter-Cisternal Continuities Involved in Intra-Golgi Transport , 2009, PLoS biology.
[77] Peter Walter,et al. Supporting Online Material for An ER-Mitochondria Tethering Complex Revealed by a Synthetic Biology Screen , 2009 .
[78] Xiaoping Zhou,et al. ERIS, an endoplasmic reticulum IFN stimulator, activates innate immune signaling through dimerization , 2009, Proceedings of the National Academy of Sciences.
[79] S. Tooze,et al. Early endosomes and endosomal coatomer are required for autophagy , 2009, The Journal of cell biology.
[80] C. Eyers. Universal sample preparation method for proteome analysis , 2009 .
[81] Y. Li,et al. The adaptor protein MITA links virus-sensing receptors to IRF3 transcription factor activation. , 2008, Immunity.
[82] L. Glimcher,et al. The endoplasmic reticulum stress response in immunity and autoimmunity , 2008, Nature Reviews Immunology.
[83] C. M. Short,et al. MPYS, a Novel Membrane Tetraspanner, Is Associated with Major Histocompatibility Complex Class II and Mediates Transduction of Apoptotic Signals , 2008, Molecular and Cellular Biology.
[84] R. Russell,et al. Differential localization of coatomer complex isoforms within the Golgi apparatus , 2007, Proceedings of the National Academy of Sciences.
[85] S. Paludan,et al. IFN-lambda: novel antiviral cytokines. , 2006, Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research.
[86] F. Wieland,et al. Novel Isotypic γ/ζ Subunits Reveal Three Coatomer Complexes in Mammals , 2004, Molecular and Cellular Biology.
[87] M. Buttmann,et al. Interferon-beta induces transient systemic IP-10/CXCL10 chemokine release in patients with multiple sclerosis. , 2004, Journal of neuroimmunology.
[88] L. Glimcher,et al. XBP-1 Regulates a Subset of Endoplasmic Reticulum Resident Chaperone Genes in the Unfolded Protein Response , 2003, Molecular and Cellular Biology.
[89] A. Lewis-Antes,et al. IFN-λs mediate antiviral protection through a distinct class II cytokine receptor complex , 2003, Nature Immunology.
[90] D. Ron,et al. Translational control in the endoplasmic reticulum stress response. , 2002, The Journal of clinical investigation.
[91] K. Nakayama,et al. Identification and characterization of novel isoforms of COP I subunits. , 2000, Journal of biochemistry.
[92] R. Duden,et al. COP I domains required for coatomer integrity, and novel interactions with ARF and ARF‐GAP , 2000, The EMBO journal.
[93] H. Ropers,et al. gamma2-COP, a novel imprinted gene on chromosome 7q32, defines a new imprinting cluster in the human genome. , 1999, Human molecular genetics.
[94] J. Darnell. Studies of IFN-induced transcriptional activation uncover the Jak-Stat pathway. , 1998, Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research.
[95] J. Katzenellenbogen,et al. Evidence that phospholipase A2 activity is required for Golgi complex and trans Golgi network membrane tubulation. , 1998, Proceedings of the National Academy of Sciences of the United States of America.
[96] R. Schekman,et al. ϵ‐COP is a structural component of coatomer that functions to stabilize α‐COP , 1998, The EMBO journal.
[97] J. Vance. Phospholipid synthesis in a membrane fraction associated with mitochondria. , 1990, The Journal of biological chemistry.
[98] J. Lippincott-Schwartz,et al. Rapid redistribution of Golgi proteins into the ER in cells treated with brefeldin A: Evidence for membrane cycling from Golgi to ER , 1989, Cell.
[99] S. Munro,et al. A C-terminal signal prevents secretion of luminal ER proteins , 1987, Cell.