Emergence of G9 serotype rotavirus as a major cause of infectious gastroenteritis in southern Taiwan.

Infectious gastroenteritis is a common illness in children. This study investigated the etiology and clinical manifestations of hospitalized children with symptoms of infectious gastroenteritis in southern Taiwan. We studied 467 consecutive patients with infectious gastroenteritis aged from 2 days to 10 years hospitalized from April 2001 to March 2002. Rotavirus was the most common etiology (57%) of infectious gastroenteritis in these patients. Bacterial infection was noted in 57 cases (12%). Rotavirus was found in 92% of nosocomial infectious gastroenteritis (p < or = 0.001). Bloody stool was a presentation of bacterial infection in 74% of cases and rotavirus gastroenteritis in 8% of cases (p < or = 0.001). The G serotype of rotavirus was identified in 87 patients. Serotype G1 was the most common (51%), followed by G9 (31%). The emergence of serotype G9 strains in rotavirus infection has not been previously reported from Taiwan. Incorporation of G9 rotavirus into vaccines should be considered.

[1]  D. Bass,et al.  Astrovirus, Adenovirus, and Rotavirus in Hospitalized Children: Prevalence and Association With Gastroenteritis , 2002, Journal of pediatric gastroenterology and nutrition.

[2]  U. Heininger,et al.  International variation in disease burden of rotavirus gastroenteritis in children with community- and nosocomially acquired infection. , 2001, The Pediatric infectious disease journal.

[3]  W. Karmaus,et al.  A prospective evaluation of community acquired gastroenteritis in paediatric practices: impact and disease burden of rotavirus infection , 2001, Archives of disease in childhood.

[4]  R. Glass,et al.  Molecular characterization of serotype G9 rotavirus strains from a global collection. , 2000, Virology.

[5]  O. Nakagomi,et al.  Apparent Re‐Emergence of Serotype G9 in 1995 among Rotaviruses Recovered from Japanese Children Hospitalized with Acute Gastroenteritis , 2000, Microbiology and immunology.

[6]  C. Kao,et al.  Enteric adenovirus infection in children in Taipei. , 2000, Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi.

[7]  J. Aranda‐Michel,et al.  Acute diarrhea: a practical review , 1999, The American Journal of Medicine.

[8]  K. Cheng,et al.  Incidence and clinical manifestations of Campylobacter enteritis in central Taiwan. , 1998, Zhonghua yi xue za zhi = Chinese medical journal; Free China ed.

[9]  Tadataka Yamada,et al.  Textbook of Gastroenterology , 1995 .

[10]  R. Baltimore,et al.  Pediatric Infectious Diseases: Principles and Practice , 1995 .

[11]  B. Chen,et al.  Rotavirus gastroenteritis in children: a clinical study of 125 patients in Hsin-Tien area. , 1991, Zhonghua Minguo xiao er ke yi xue hui za zhi [Journal]. Zhonghua Minguo xiao er ke yi xue hui.

[12]  R. Glass,et al.  Polymerase chain reaction amplification and typing of rotavirus nucleic acid from stool specimens , 1990, Journal of clinical microbiology.

[13]  Chen Ts,et al.  Clinical observations of infants and children with rotavirus gastroenteritis in southern Taiwan , 1988 .

[14]  L. Tsai,et al.  [Clinical observations of infants and children with rotavirus gastroenteritis in southern Taiwan]. , 1988, Gaoxiong yi xue ke xue za zhi = The Kaohsiung journal of medical sciences.

[15]  D. Wingate.  Gastrointestinal disease: pathophysiology, diagnosis, management , 1984 .