LOSS OF THE TUMOR SUPPRESSOR, TP53, ENHANCES THE ANDROGEN RECEPTOR MEDIATED ONCOGENIC TRANSFORMATION AND TUMOR DEVELOPMENT IN THE MOUSE PROSTATE
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R. Cardiff | Zijie Sun | J. Geradts | Huiqing Wu | S. You | Erika Hooker | Yongfeng He | Julie Yang | Daniel T Johnson | Junhee Yoon | Dong-Hoon Lee | Won Kyung Kim | Joseph Aldahl | Vien Le | Eun-Jeong Yu
[1] Chris J. Stubben,et al. The Lineage‐Defining Transcription Factors SOX2 and NKX2–1 Determine Lung Cancer Cell Fate and Shape the Tumor Immune Microenvironment , 2018, Immunity.
[2] Joshua M. Stuart,et al. Clinical and Genomic Characterization of Treatment-Emergent Small-Cell Neuroendocrine Prostate Cancer: A Multi-institutional Prospective Study. , 2018, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[3] Henry W. Long,et al. A Somatically Acquired Enhancer of the Androgen Receptor Is a Noncoding Driver in Advanced Prostate Cancer , 2018, Cell.
[4] Joshua M. Stuart,et al. Genomic Hallmarks and Structural Variation in Metastatic Prostate Cancer , 2018, Cell.
[5] Menggang Yu,et al. Associations of Luminal and Basal Subtyping of Prostate Cancer With Prognosis and Response to Androgen Deprivation Therapy , 2017, JAMA oncology.
[6] M. Rubin,et al. SOX2 promotes lineage plasticity and antiandrogen resistance in TP53- and RB1-deficient prostate cancer , 2017, Science.
[7] E. Klein,et al. Integrated Classification of Prostate Cancer Reveals a Novel Luminal Subtype with Poor Outcome. , 2016, Cancer research.
[8] Måns Magnusson,et al. MultiQC: summarize analysis results for multiple tools and samples in a single report , 2016, Bioinform..
[9] P. V. van Diest,et al. Cytokeratin and protein expression patterns in squamous cell carcinoma of the oral cavity provide evidence for two distinct pathogenetic pathways , 2016, Oncology letters.
[10] J. Mesirov,et al. The Molecular Signatures Database Hallmark Gene Set Collection , 2015 .
[11] Joshua M. Stuart,et al. A basal stem cell signature identifies aggressive prostate cancer phenotypes , 2015, Proceedings of the National Academy of Sciences.
[12] Lawrence D. True,et al. Integrative Clinical Genomics of Advanced Prostate Cancer , 2015, Cell.
[13] M. Tupone,et al. SNAI2/Slug gene is silenced in prostate cancer and regulates neuroendocrine differentiation, metastasis-suppressor and pluripotency gene expression , 2015, Oncotarget.
[14] R. Luong,et al. Androgen Signaling Is a Confounding Factor for β-catenin-mediated Prostate Tumorigenesis , 2015, Oncogene.
[15] Samantha A. Morris,et al. CellNet: Network Biology Applied to Stem Cell Engineering , 2014, Cell.
[16] D. Hwang,et al. Identification of key regulators for the migration and invasion of rheumatoid synoviocytes through a systems approach , 2013, Proceedings of the National Academy of Sciences.
[17] Aaron R Cooper,et al. Prostate cancer originating in basal cells progresses to adenocarcinoma propagated by luminal-like cells , 2013, Proceedings of the National Academy of Sciences.
[18] D. Zheng,et al. ETS factors reprogram the androgen receptor cistrome and prime prostate tumorigenesis in response to PTEN loss , 2013, Nature Medicine.
[19] Gerald C. Chu,et al. Animal models of human prostate cancer: the consensus report of the New York meeting of the Mouse Models of Human Cancers Consortium Prostate Pathology Committee. , 2013, Cancer research.
[20] R. Luong,et al. Conditional Deletion of the Pten Gene in the Mouse Prostate Induces Prostatic Intraepithelial Neoplasms at Early Ages but a Slow Progression to Prostate Tumors , 2013, PloS one.
[21] K. Hochedlinger,et al. The sox family of transcription factors: versatile regulators of stem and progenitor cell fate. , 2013, Cell stem cell.
[22] Yuzhuo Wang,et al. Deletion of Leucine Zipper Tumor Suppressor 2 (Lzts2) Increases Susceptibility to Tumor Development* , 2012, The Journal of Biological Chemistry.
[23] Hui Zhou,et al. ChIPBase: a database for decoding the transcriptional regulation of long non-coding RNA and microRNA genes from ChIP-Seq data , 2012, Nucleic Acids Res..
[24] Benjamin E. Gross,et al. The cBio cancer genomics portal: an open platform for exploring multidimensional cancer genomics data. , 2012, Cancer discovery.
[25] Scott C. Williams,et al. Radioimmunotherapy of Non-Hodgkin’s Lymphoma: From the ‘Magic Bullets’ to ‘Radioactive Magic Bullets’ , 2011, The Yale journal of biology and medicine.
[26] J. McKenney,et al. Conditional Expression of the Androgen Receptor Induces Oncogenic Transformation of the Mouse Prostate* , 2011, The Journal of Biological Chemistry.
[27] Helga Thorvaldsdóttir,et al. Molecular signatures database (MSigDB) 3.0 , 2011, Bioinform..
[28] Li Chen,et al. hmChIP: a database and web server for exploring publicly available human and mouse ChIP-seq and ChIP-chip data , 2011, Bioinform..
[29] Avi Ma'ayan,et al. ChEA: transcription factor regulation inferred from integrating genome-wide ChIP-X experiments , 2010, Bioinform..
[30] Yuchen Bai,et al. Research Resource: The androgen receptor modulates expression of genes with critical roles in muscle development and function. , 2010, Molecular endocrinology.
[31] M. Robinson,et al. A scaling normalization method for differential expression analysis of RNA-seq data , 2010, Genome Biology.
[32] J. Mirosevich,et al. Prostate epithelial cell fate. , 2008, Differentiation; research in biological diversity.
[33] R. Shamir,et al. Transcription factor and microRNA motif discovery: the Amadeus platform and a compendium of metazoan target sets. , 2008, Genome research.
[34] G. Martin,et al. A Cre transgene active in developing endodermal organs, heart, limb, and extra‐ocular muscle , 2008, Genesis.
[35] Jane Lee,et al. The novel PIAS-like protein hZimp10 is a transcriptional co-activator of the p53 tumor suppressor , 2007, Nucleic acids research.
[36] A. Flesken-Nikitin,et al. Prostate cancer associated with p53 and Rb deficiency arises from the stem/progenitor cell-enriched proximal region of prostatic ducts. , 2007, Cancer research.
[37] David C. Corney,et al. Synergy of p53 and Rb deficiency in a conditional mouse model for metastatic prostate cancer. , 2006, Cancer research.
[38] Pablo Tamayo,et al. Gene set enrichment analysis: A knowledge-based approach for interpreting genome-wide expression profiles , 2005, Proceedings of the National Academy of Sciences of the United States of America.
[39] T. Ratliff. Molecular Determinants of Resistance to Antiandrogen Therapy , 2004 .
[40] C. Heinlein,et al. Androgen receptor in prostate cancer. , 2004, Endocrine reviews.
[41] P. Nelson,et al. Prostate-specific deletion of the murine Pten tumor suppressor gene leads to metastatic prostate cancer. , 2003, Cancer cell.
[42] John D. Storey. A direct approach to false discovery rates , 2002 .
[43] C. Huggins,et al. Studies on prostatic cancer. I. The effect of castration, of estrogen and of androgen injection on serum phosphatases in metastatic carcinoma of the prostate. 1941. , 2002, The Journal of urology.
[44] J Isola,et al. Androgen receptor gene amplification: a possible molecular mechanism for androgen deprivation therapy failure in prostate cancer. , 1997, Cancer research.
[45] C. Prives,et al. p53: puzzle and paradigm. , 1996, Genes & development.
[46] E. Gelmann,et al. p53 oncogene mutations in human prostate cancer specimens. , 1994, The Journal of urology.
[47] S. Hilsenbeck,et al. p53 is mutated in a subset of advanced-stage prostate cancers. , 1993, Cancer research.
[48] N. Kyprianou,et al. Activation of programmed cell death in the rat ventral prostate after castration. , 1988, Endocrinology.
[49] J. Mesirov,et al. The Molecular Signatures Database (MSigDB) hallmark gene set collection. , 2015, Cell systems.
[50] R. Vessella,et al. Molecular determinants of resistance to antiandrogen therapy , 2004, Nature Medicine.
[51] P. Kleihues,et al. Tumors associated with p53 germline mutations: a synopsis of 91 families. , 1997, The American journal of pathology.