Computational study of particle deposition in patient specific geometries

The present work focuses on the study of particle deposition in segments of the cardiovascular system. In particular, the geometry of an iliac bifurcation is reconstructed from medical imaging data and the flow fields of both blood and particles are obtained using Computational Fluid Particle Dynamics techniques. Particle convection, diffusion and inertia are taken into account in the simulations. The numerical experiments indicate that diffusion dominates deposition and only 10% of the injected particles deposit in the bifurcation. Both blood flow field and the characteristics of the patient specific geometry influence the particle deposition sites. Overall, the proposed methodology could become a useful tool for the design and optimization of biomedical applications.

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