Prediction of hip fractures from pelvic radiographs: The study of osteoporotic fractures

To determine whether simple measurements made on conventional radiographs of the hip could predict hip fractures, we obtained pelvic radiographs on 9704 white women age 65 or older. We analyzed the radiographs of all 162 women who subsequently suffered a hip fracture and 162 randomly selected women who did not. Adjusting for age, four measurements independently predicted hip fracture: reduced thickness of the femoral shaft cortex (odds ratio 1.7 per standard deviation; 95% confidence interval 1.2, 2.3) and of the femoral neck cortex (1.4 per standard deviation; 1.0, 1.9), reduction in an index of tensile trabeculae (2.0 per unit; 1.4, 2.9), and wider trochanteric region (1.4 per standard deviation; 1.0, 2.0). The combination of these four measurements predicted hip fracture at least as strongly as did measurement of bone density of the femoral neck (areas of the receiver‐operating characteristic curve = 0.81 and 0.80, respectively). We conclude that simple measurements made on pelvic radiographs predict hip fractures as well as bone density of the hip.

[1]  C C Glüer,et al.  Simple measurement of femoral geometry predicts hip fracture: The study of osteoporotic fractures , 1993, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

[2]  S. Cummings,et al.  Bone density at various sites for prediction of hip fractures , 1993, The Lancet.

[3]  S. Cummings,et al.  The accuracy of self-report of fractures in elderly women: evidence from a prospective study. , 1992, American journal of epidemiology.

[4]  H. Uhthoff,et al.  Pattern of bone loss of the proximal femur: A radiologic, densitometric, and histomorphometric study , 1991, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.

[5]  M. Fukunaga,et al.  Assessment of bone mass by image analysis of metacarpal bone roentgenograms: a quantitative digital image processing (DIP) method. , 1990, Radiation medicine.

[6]  Harry K. Genant,et al.  Appendicular Bone Density and Age Predict Hip Fracture in Women , 1990 .

[7]  H K Genant,et al.  Appendicular bone density and age predict hip fracture in women. The Study of Osteoporotic Fractures Research Group. , 1990, JAMA.

[8]  C. Slemenda,et al.  Baseline measurement of bone mass predicts fracture in white women. , 1989, Annals of internal medicine.

[9]  C. Cooper,et al.  Osteoporosis, falls, and age in fracture of the proximal femur. , 1987, British medical journal.

[10]  P. Ross,et al.  Prediction of postmenopausal fracture risk with use of bone mineral measurements. , 1985, American journal of obstetrics and gynecology.

[11]  H. Bohr,et al.  Bone mineral content of femoral bone and the lumbar spine measured in women with fracture of the femoral neck by dual photon absorptiometry. , 1983, Clinical orthopaedics and related research.

[12]  J. Hanley,et al.  A method of comparing the areas under receiver operating characteristic curves derived from the same cases. , 1983, Radiology.

[13]  B. Vernon‐roberts,et al.  Absence of metabolic bone disease in the proximal femur in patients with fracture of the femoral neck. , 1982, The Journal of bone and joint surgery. British volume.

[14]  C. Miller,et al.  Survival and ambulation following hip fracture. , 1978, The Journal of bone and joint surgery. American volume.

[15]  B. Nilsson,et al.  Cortical Index of the Femoral Neck , 1977, Acta radiologica: diagnosis.

[16]  C. Johnston,et al.  Femoral trabecular-pattern index and bone mineral content measurement by photon absorption in senile osteoporosis. , 1976, The Journal of bone and joint surgery. American volume.

[17]  J. F. Williams,et al.  Prediction of the strength of the neck of femur from its radiological appearance. , 1975, Biomedical engineering.

[18]  B. Riggs,et al.  Femoral trabecular-pattern index for evaluation of spinal osteoporosis. , 1972, Annals of internal medicine.

[19]  M. Singh,et al.  Changes in trabecular pattern of the upper end of the femur as an index of osteoporosis. , 1970, The Journal of bone and joint surgery. American volume.

[20]  P. Virtama,et al.  Bone pattern of the femoral neck as a measure of bone density and susceptibility to hip fractures. , 1969, Annals of clinical research.

[21]  B E NORDIN,et al.  The radiological diagnosis of osteoporosis: a new approach. , 1960, Clinical radiology.

[22]  C. Cooper,et al.  Evaluation of the Singh index and femoral calcar width as epidemiological methods for measuring bone mass in the femoral neck. , 1986, Clinical radiology.

[23]  J. Dequeker,et al.  Femoral trabecular patterns in asymptomatic spinal osteoporosis and femoral neck fracture. , 1974, Clinical radiology.