CHANGES OF URINARY DOPAMINE EXCRETION EARLY AFTER BALLOON MITRAL COMMISSUROTOMY IN MITRAL STENOSIS

1. In order to investigate the changes of reduced urinary free dopamine excretion (uDA) in heart failure, 15 patients with symptomatic mitral stenosis were investigated on their uDA, endogenous creatinine (Cr) clearance, urinary excretion of sodium (UNaV), fractional excretion of sodium (FENa), plasma noradrenaline (pNA) and plasma L‐dopa concentration before and early after percutaneous transvenous mitral commissurotomy (PTMC) by the clearance study. The delivery of L‐dopa to renal proximal tubules (plasma L‐dopa × Cr clearance), and the conversion ratio of plasma L‐dopa to urinary dopamine in the kidney [uDA/(plasma L‐dopa × Cr clearance)] were also estimated.

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