The neurobiology of blindsight

Some patients can respond to visual stimuli presented within their clinically absolute visual field defects that have been caused by partial destruction of striate cortex. This puzzling phenomenon of looking, pointing, detecting and discriminating without seeing has been called blindsight, and has fascinated philosophers and neuroscientists alike as a spotlight on the nature of unconscious or covert awareness, and the means it provides of studying the visual information carried by pathways other than the major route through the striate cortex.

[1]  K. Yoshida,et al.  The afferent and efferent organization of the lateral geniculo‐prestriate pathways in the macaque monkey , 1981, The Journal of comparative neurology.

[2]  H. Vanegas,et al.  Comparative neurology of the optic tectum , 1984 .

[3]  Donald J. Lyle,et al.  The Retinal Ganglion Cell Layer , 1964 .

[4]  A. Cowey Atrophy of Retinal Ganglion Cells after Removal of Striate Cortex in a Rhesus Monkey , 1974, Perception.

[5]  J. Simpson The accessory optic system. , 1984, Annual review of neuroscience.

[6]  M. Perenin,et al.  Visual function within the hemianopic field following early cerebral hemidecortication in man—I. Spatial localization , 1978, Neuropsychologia.

[7]  J. Bullier,et al.  Visual activity in area V2 during reversible inactivation of area 17 in the macaque monkey. , 1989, Journal of neurophysiology.

[8]  Ernst Pöppel,et al.  Signal detection analysis of residual vision in a field defect due to a post-geniculate lesion , 1985, Neuropsychologia.

[9]  A. Hendrickson,et al.  Hypertrophy of neurons in dorsal lateral geniculate nucleus following striate cortex lesions in infant monkeys , 1982, Neuroscience Letters.

[10]  R H Wurtz,et al.  Role of striate cortex and superior colliculus in visual guidance of saccadic eye movements in monkeys. , 1977, Journal of neurophysiology.

[11]  R. Harwerth,et al.  Red-Green Cone Interactions in the Increment-Threshold Spectral Sensitivity of Primates , 1971, Science.

[12]  D. Hubel,et al.  Segregation of form, color, movement, and depth: anatomy, physiology, and perception. , 1988, Science.

[13]  J. M. Buren Trans-synaptic retrograde degeneration in the visual system of primates , 1963, Journal of neurology, neurosurgery, and psychiatry.

[14]  K H Ruddock,et al.  Residual vision in patients with retrogeniculate lesions of the visual pathways. , 1987, Brain : a journal of neurology.

[15]  D. Ferrier The Functions of the Brain , 1887, Edinburgh Medical Journal.

[16]  L. Mihailović,et al.  Changes in the numbers of neurons and glial cells in the lateral geniculate nucleus of the monkey during retrograde cell degeneration , 1971, The Journal of comparative neurology.

[17]  A. Cowey,et al.  Transneuronal retrograde degeneration of retinal ganglion cells after damage to striate cortex in macaque monkeys: Selective loss of Pβ cells , 1989, Neuroscience.

[18]  Charles J. Campbell,et al.  The Retinal Ganglion Cell Layer. , 1965 .

[19]  J. Kaas,et al.  Parameters affecting the loss of ganglion cells of the retina following ablations of striate cortex in primates , 1989, Visual Neuroscience.

[20]  C. A. Marzi,et al.  Spatial summation across the vertical meridian in hemianopics: A test of blindsight , 1986, Neuropsychologia.

[21]  R. Held,et al.  Residual Visual Function after Brain Wounds involving the Central Visual Pathways in Man , 1973, Nature.

[22]  D. C. Harrison Progress in Physiology , 1959, Nature.

[23]  D. Burman,et al.  Opponent-color responses in macaque extrageniculate visual pathways: the lateral pulvinar , 1983, Brain Research.

[24]  A. Cowey,et al.  Residual target detection as a function of stimulus size. , 1989, Brain : a journal of neurology.

[25]  Alan Cowey,et al.  Wavelength sensitivity in blindsight , 1989, Nature.

[26]  L. Weiskrantz Blindsight : a case study and implications , 1986 .

[27]  K H Ruddock,et al.  Human visual responses in the absence of the geniculo-calcarine projection. , 1980, Brain : a journal of neurology.

[28]  Fbederick P. Gault Progress in Physiological Psychology , 1967, The Yale Journal of Biology and Medicine.

[29]  N. Logothetis,et al.  Neuronal correlates of subjective visual perception. , 1989, Science.

[30]  R W Guillery,et al.  Patterns of synaptic interconnections in the dorsal lateral geniculate nucleus of cat and monkey: a brief review. , 1971, Vision research.

[31]  A. Marcel Conscious and unconscious perception: An approach to the relations between phenomenal experience and perceptual processes , 1983, Cognitive Psychology.

[32]  L Weiskrantz,et al.  Residual vision in a scotoma. A follow-up study of 'form' discrimination. , 1987, Brain : a journal of neurology.

[33]  G. Holmes DISTURBANCES OF VISION BY CEREBRAL LESIONS , 1918, The British journal of ophthalmology.

[34]  D. Whitteridge,et al.  Arborisation pattern and postsynaptic targets of physiologically identified thalamocortical afferents in striate cortex of the macaque monkey , 1989, The Journal of comparative neurology.

[35]  J. Sprague,et al.  Progress in physiological psychology , 1966 .

[36]  A. Cowey,et al.  Retinal ganglion cells that project to the superior colliculus and pretectum in the macaque monkey , 1984, Neuroscience.

[37]  A. Hendrickson,et al.  Age correlated differences in the amount of retinal degeneration after striate cortex lesions in monkeys. , 1981, Investigative ophthalmology & visual science.

[38]  S. Kadoya,et al.  Collicular unit responses to monochromatic stimulation in squirrel monkey. , 1971, Brain research.

[39]  K. H. Ruddock,et al.  Visual discrimination of target displacement remains after damage to the striate cortex in humans , 1986, Nature.

[40]  P. Schiller,et al.  Properties and tectal projections of monkey retinal ganglion cells. , 1977, Journal of neurophysiology.

[41]  C. Gross,et al.  Afferent basis of visual response properties in area MT of the macaque. II. Effects of superior colliculus removal , 1990, The Journal of neuroscience : the official journal of the Society for Neuroscience.

[42]  A. M. V. Vliet,et al.  Visual reactions in a case of long-lasting cortical blindness , 1971 .

[43]  Richard Latto,et al.  Is blindsight an effect of scattered light, spared cortex, and near-threshold vision? , 1983, Behavioral and Brain Sciences.

[44]  A. Marcel Conscious and unconscious perception: Experiments on visual masking and word recognition , 1983, Cognitive Psychology.

[45]  G. Blasdel,et al.  Termination of afferent axons in macaque striate cortex , 1983, The Journal of neuroscience : the official journal of the Society for Neuroscience.

[46]  M. Yukie,et al.  Direct projection from the dorsal lateral geniculate nucleus to the prestriate cortex in macaque monkeys , 1981, The Journal of comparative neurology.

[47]  D. B. Bender,et al.  Visual activation of neurons in inferotemporal cortex depends on striate cortex and forebrain commissures. , 1975, Journal of neurophysiology.

[48]  P. Stoerig,et al.  Chromaticity and achromaticity. Evidence for a functional differentiation in visual field defects. , 1987, Brain : a journal of neurology.

[49]  M. Perenin Visual function within the hemianopic field following early cerebral hemidecortication in man — II. Pattern discrimination , 1978, Neuropsychologia.

[50]  Ernst Pöppel,et al.  Long-range colour-generating interactions across the retina , 1986, Nature.

[51]  M. Ptito,et al.  Visual discrimination in hemispherectomized patients , 1987, Neuropsychologia.

[52]  D. B. Bender Electrophysiological and behavioral experiments on the primate pulvinar. , 1988, Progress in brain research.

[53]  C. Gross,et al.  Afferent basis of visual response properties in area MT of the macaque. I. Effects of striate cortex removal , 1989, The Journal of neuroscience : the official journal of the Society for Neuroscience.

[54]  L Weiskrantz,et al.  Visual capacity in the hemianopic field following a restricted occipital ablation. , 1974, Brain : a journal of neurology.

[55]  A. Cowey,et al.  Retinal ganglion cells that project to the dorsal lateral geniculate nucleus in the macaque monkey , 1984, Neuroscience.