Genetic analysis of polymorphisms in biologically relevant candidate genes in patients with abdominal aortic aneurysms.

[1]  G. Pals,et al.  Genome Scan for Familial Abdominal Aortic Aneurysm Using Sex and Family History as Covariates Suggests Genetic Heterogeneity and Identifies Linkage to Chromosome 19q13 , 2004, Circulation.

[2]  K. Kochanek,et al.  Deaths: preliminary data for 2002. , 2004, National vital statistics reports : from the Centers for Disease Control and Prevention, National Center for Health Statistics, National Vital Statistics System.

[3]  Gregory T. Jones,et al.  Functional matrix metalloproteinase-9 polymorphism (C-1562T) associated with abdominal aortic aneurysm. , 2003, Journal of vascular surgery.

[4]  C. Munaut,et al.  TIMP-2 and PAI-1 mRNA levels are lower in aneurysmal as compared to athero-occlusive abdominal aortas. , 2003, Cardiovascular research.

[5]  Robert W. Thompson,et al.  Prospects for the Medical Management of Abdominal Aortic Aneurysms , 2003, Vascular and endovascular surgery.

[6]  P. McKeigue,et al.  For Personal Use. Only Reproduce with Permission from the Lancet Publishing Group. Problems of Reporting Genetic Associations with Complex Outcomes , 2022 .

[7]  Gerard Tromp,et al.  Familial abdominal aortic aneurysms: collection of 233 multiplex families. , 2003, Journal of vascular surgery.

[8]  J. Strong,et al.  MMP13 promoter polymorphism is associated with atherosclerosis in the abdominal aorta of young black males. , 2002, Matrix biology : journal of the International Society for Matrix Biology.

[9]  H. Kuivaniemi,et al.  Primer-extension preamplified DNA is a reliable template for genotyping. , 2002, Clinical chemistry.

[10]  G. Pals,et al.  Familial abdominal aortic aneurysm: a systematic review of a genetic background. , 2002, European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery.

[11]  M. Thompson,et al.  Ubiquitous Elevation of Matrix Metalloproteinase-2 Expression in the Vasculature of Patients With Abdominal Aneurysms , 2001, Circulation.

[12]  S. Wilson,et al.  Abdominal aortic aneurysm in women. , 2001, Journal of vascular surgery.

[13]  D. Greaves,et al.  Identification of Novel, Functional Genetic Variants in the Human Matrix Metalloproteinase-2 Gene , 2001, The Journal of Biological Chemistry.

[14]  K. Angquist,et al.  Activity of matrix metalloproteinase-2 and -9 in abdominal aortic aneurysms. Relation to size and rupture. , 2000, European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery.

[15]  D. Hovsepian,et al.  Elevated plasma levels of matrix metalloproteinase-9 in patients with abdominal aortic aneurysms: a circulating marker of degenerative aneurysm disease. , 2000, Journal of vascular and interventional radiology : JVIR.

[16]  G. Pals,et al.  Familial Abdominal Aortic Aneurism , 2000 .

[17]  S. Shapiro,et al.  Targeted gene disruption of matrix metalloproteinase-9 (gelatinase B) suppresses development of experimental abdominal aortic aneurysms. , 2000, The Journal of clinical investigation.

[18]  J. Mužík,et al.  Identification of novel common polymorphisms in the promoter region of the TIMP-3 gene in Czech population. , 2000, Molecular and cellular probes.

[19]  A M Zeiher,et al.  Allele-specific regulation of matrix metalloproteinase-12 gene activity is associated with coronary artery luminal dimensions in diabetic patients with manifest coronary artery disease. , 2000, Circulation research.

[20]  H. Kuivaniemi,et al.  Genetic analysis of MMP3, MMP9, and PAI-1 in Finnish patients with abdominal aortic or intracranial aneurysms. , 1999, Biochemical and biophysical research communications.

[21]  A. Evans,et al.  Functional polymorphism in the regulatory region of gelatinase B gene in relation to severity of coronary atherosclerosis. , 1999, Circulation.

[22]  H. Kuivaniemi,et al.  Analysis of coding sequences for tissue inhibitor of metalloproteinases 1 (TIMP1) and 2 (TIMP2) in patients with aneurysms. , 1999, Matrix biology : journal of the International Society for Matrix Biology.

[23]  J. Gusella,et al.  A single nucleotide polymorphism in the matrix metalloproteinase-1 promoter creates an Ets binding site and augments transcription. , 1998, Cancer research.

[24]  W. Pearce,et al.  Expression of matrix metalloproteinases and their inhibitors in aneurysms and normal aorta. , 1997, Surgery.

[25]  P. Libby,et al.  Evidence for altered balance between matrix metalloproteinases and their inhibitors in human aortic diseases. , 1997, Circulation.

[26]  H. Kuivaniemi,et al.  Candidate Genes for Abdominal Aortic Aneurysms a , 1996, Annals of the New York Academy of Sciences.

[27]  E M Wijsman,et al.  Toward localization of the Werner syndrome gene by linkage disequilibrium and ancestral haplotyping: lessons learned from analysis of 35 chromosome 8p11.1-21.1 markers. , 1996, American journal of human genetics.

[28]  A. Henney,et al.  Progression of Coronary Atherosclerosis Is Associated with a Common Genetic Variant of the Human Stromelysin-1 Promoter Which Results in Reduced Gene Expression* , 1996, The Journal of Biological Chemistry.

[29]  N. Risch,et al.  A comparison of linkage disequilibrium measures for fine-scale mapping. , 1995, Genomics.

[30]  L. Koulischer,et al.  Aneurysms of the abdominal aorta: familial and genetic aspects in three hundred thirteen pedigrees. , 1995, Journal of vascular surgery.

[31]  D. Steed,et al.  Characterization of a dinucleotide repeat in the 92 kDa type IV collagenase gene (CLG4B), localization of CLG4B to chromosome 20 and the role of CLG4B in aortic aneurysmal disease , 1995, Annals of human genetics.

[32]  D. Curtis,et al.  Monte Carlo tests for associations between disease and alleles at highly polymorphic loci , 1995, Annals of human genetics.

[33]  J. Scholes,et al.  Cellular localization of matrix metalloproteinases in the abdominal aortic aneurysm wall. , 1994, Journal of vascular surgery.

[34]  J. Rosenbloom,et al.  A to G polymorphism in ELN gene. , 1991, Nucleic acids research.

[35]  W. Marks,et al.  Decreased tissue inhibitor of metalloproteinases (TIMP) in abdominal aortic aneurysm tissue: a preliminary report. , 1991, The Journal of surgical research.

[36]  Caren Kleinert,et al.  C to T polymorphism in exon 33 of the COL3A1 gene. , 1991, Nucleic acids research.

[37]  W. Humphreys,et al.  Aneurysms of the abdominal aorta. , 1979, British journal of hospital medicine.

[38]  Martin A. Clifton Familial abdominal aortic aneurysms , 1977, The British journal of surgery.

[39]  Pak Chung Sham,et al.  Genetic Power Calculator: design of linkage and association genetic mapping studies of complex traits , 2003, Bioinform..

[40]  Z. Werb,et al.  How matrix metalloproteinases regulate cell behavior. , 2001, Annual review of cell and developmental biology.

[41]  T. Spector,et al.  Genetic control of the circulating concentration of transforming growth factor type beta1. , 1999, Human molecular genetics.

[42]  D. Steed,et al.  On the inheritance of abdominal aortic aneurysm. , 1991, American journal of human genetics.