Milling is widely used to machine the structures with low-rigidity in astronautic and aeronautic industries, while chatter vibration, which is a great limitation and a serious problem, is easy to occur in this kind of process due to the weak stiffness of the structures. To solve the machining problems caused by chatter, prediction and suppression are two important methods that are commonly used by researchers and industry engineers. This article reviews the study progresses on the prediction and suppression of the chatter occurring in milling process of the low-rigidity structure. The dynamic model, acquisition of dynamic parameters, and suppression techniques are introduced. Besides, the problems and the outlooks of the future coming research are also given in the conclusions.