Use of Pervaporation-Bioreactor Hybrid Processes in Biotechnology

Pervaporation is a membrane separation process with considerable innovative possibilities in the area of biotechnology. Above all, the combination of bioreactor and pervaporation has potential in the longer term as an alternative to conventional batch processes. This article considers the state of the art pervaporation-bioreactor hybrid processes. The possible applications of such hybrid processes are discussed and compared with conventional processes. It becomes apparent that the use of pervaporation-bioreactor hybrid processes can avoid product inhibition and greatly enhance the productivity of biotechnological processes.

[1]  Frank Lipnizki,et al.  Pervaporation-based hybrid process: a review of process design, applications and economics , 1999 .

[2]  F. Widmer,et al.  Entwicklung membranunterstützter Reaktionsprozesse , 1996 .

[3]  I. Souchon,et al.  EXTRACTION OF BENZALDEHYDE FROM FERMENTATION BROTH BY PERVAPORATION , 1996 .

[4]  W. Koros,et al.  Terminology for membranes and membrane processes (IUPAC Recommendations 1996) , 1996 .

[5]  K. Schügerl,et al.  Integrierte biotechnologische Produktionsprozesse , 1994 .

[6]  T. Matsuura,et al.  A Study of Polydimethylsiloxane/Aromatic Polyamide Laminated Membranes for Separation of Acetic Acid/Water Mixtures by Pervaporation Process , 1994 .

[7]  Q Geng,et al.  Pervaporative butanol fermentation by Clostridium acetobutylicum B18 , 1994, Biotechnology and bioengineering.

[8]  H. Chmiel.  Integration von Membrantrennverfahren in kontinuierliche Bioprozesse , 1992 .

[9]  K. Ch. A. M. Luyben,et al.  Ethanol production in an integrated process of fermentation and ethanol recovery by pervaporation , 1992 .

[10]  N. Qureshi,et al.  Application of novel technology to the abe fermentation process , 1992 .

[11]  C Linder,et al.  Continuous ethanol production by immobilized yeast reactor coupled with membrane pervaporation unit , 1991, Biotechnology and bioengineering.

[12]  A. Friedl,et al.  Continuous acetone‐butanol‐ethanol (ABE) fermentation using immobilized cells of Clostridium acetobutylicum in a packed bed reactor and integration with product removal by pervaporation , 1991, Biotechnology and bioengineering.

[13]  K. Ch. A. M. Luyben,et al.  Integration of pervaporation and continuous butanol fermentation with immobilized cells: II: Mathematical modelling and simulations , 1991 .

[14]  K. Ch. A. M. Luyben,et al.  Integration of pervaporation and continuous butanol fermentation with immobilized cells. I: Experimental results , 1991 .

[15]  Y. Mori,et al.  Ethanol production from starch in a pervaporation membrane bioreactor using Clostridium thermohydrosulfuricum , 1990, Biotechnology and bioengineering.

[16]  H. Strathmann,et al.  Use of Pervaporation in the Continuous Fermentation of Acetone, Butanol, and Ethanol , 1989 .

[17]  Klaus Kimmerle,et al.  Entfernung von Lösungsmitteln aus Bioproduktionsprozessen , 1988 .

[18]  L. Puigjaner,et al.  Study of butanol extraction through pervaporation in acetobutylic fermentation. , 1987, Biotechnology and bioengineering.

[19]  Shoji Kimura,et al.  Continuous ethanol extraction by pervaporation from a membrane bioreactor , 1987 .

[20]  Edward L Cussler,et al.  Terminology for membranes and membrane processes (IUPAC Recommendations 1996) , 1996 .

[21]  K. Luyben,et al.  Ethanol production in an integrated fermentation/membrane system. Process simulations and economics , 1993 .

[22]  K. W. Böddeker,et al.  Recovery of 6-pentyl-alpha-pyrone from Trichoderma viride culture medium by perevaporation , 1992 .

[23]  K. Kimmerle,et al.  Recovery and concentration of high vapour pressure bioproducts by means of controlled membrane separation , 1988 .