MicroRNA302-367-PI3K-PTEN-AKT-mTORC1 pathway promotes the development of cardiac hypertrophy through controlling autophagy
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J. Piao | Lian-hua Jin | Yan Zhou | Lizhi Han
[1] Jun Zhang,et al. MiR-129-5p inhibits autophagy and apoptosis of H9c2 cells induced by hydrogen peroxide via the PI3K/AKT/mTOR signaling pathway by targeting ATG14. , 2018, Biochemical and biophysical research communications.
[2] Saitian Zeng,et al. miRNA-145 inhibits myocardial infarction-induced apoptosis through autophagy via Akt3/mTOR signaling pathway in vitr and in vivo , 2018, International journal of molecular medicine.
[3] E. Morrisey,et al. Elevated Expression of miR302-367 in Endothelial Cells Inhibits Developmental Angiogenesis via CDC42/CCND1 Mediated Signaling Pathways , 2018, Theranostics.
[4] P. Carmeliet,et al. Inhibition of MicroRNA-146a and Overexpression of Its Target Dihydrolipoyl Succinyltransferase Protect Against Pressure Overload-Induced Cardiac Hypertrophy and Dysfunction , 2017, Circulation.
[5] Zuoren Yu,et al. miR-302/367/LATS2/YAP pathway is essential for prostate tumor-propagating cells and promotes the development of castration resistance , 2017, Oncogene.
[6] Xue-chao Wang,et al. MicroRNA-365 accelerates cardiac hypertrophy by inhibiting autophagy via the modulation of Skp2 expression. , 2017, Biochemical and biophysical research communications.
[7] Xiuzhen Han,et al. The role of autophagy in angiotensin II-induced pathological cardiac hypertrophy. , 2016, Journal of molecular endocrinology.
[8] Priyatansh Gurha. MicroRNAs in cardiovascular disease , 2016, Current opinion in cardiology.
[9] Y. Maejima,et al. Drp1-Dependent Mitochondrial Autophagy Plays a Protective Role Against Pressure Overload–Induced Mitochondrial Dysfunction and Heart Failure , 2016, Circulation.
[10] K. Poss,et al. Building and re-building the heart by cardiomyocyte proliferation , 2016, Development.
[11] Z. Gao,et al. The miR-302/367 cluster: a comprehensive update on its evolution and functions , 2015, Open Biology.
[12] Jian-Fu Chen,et al. MiR-302/367 regulate neural progenitor proliferation, differentiation timing, and survival in neurulation. , 2015, Developmental biology.
[13] Yan-li Zhou,et al. Non-coding RNAs in cardiac regeneration , 2015, Oncotarget.
[14] Yongkyu Park,et al. miR-206 Mediates YAP-Induced Cardiac Hypertrophy and Survival. , 2015, Circulation research.
[15] N. Hou,et al. miR-199a impairs autophagy and induces cardiac hypertrophy through mTOR activation , 2015, Cell Death and Differentiation.
[16] B. Groner,et al. Expression of the miR‐302/367 cluster in glioblastoma cells suppresses tumorigenic gene expression patterns and abolishes transformation related phenotypes , 2015, International journal of cancer.
[17] Tao Wang,et al. A microRNA-Hippo pathway that promotes cardiomyocyte proliferation and cardiac regeneration in mice , 2015, Science Translational Medicine.
[18] B. C. Bernardo,et al. Pathophysiology of cardiac hypertrophy and heart failure: signaling pathways and novel therapeutic targets , 2015, Archives of Toxicology.
[19] B. Rothermel,et al. Autophagy in cardiovascular biology. , 2015, The Journal of clinical investigation.
[20] Sharad Kumar,et al. Autophagy as a pro‐death pathway , 2015, Immunology and cell biology.
[21] Wen-Hsiung Li,et al. Functional evolution of cardiac microRNAs in heart development and functions. , 2014, Molecular biology and evolution.
[22] Zhonghan Li,et al. Therapeutic targeting of microRNAs: current status and future challenges , 2014, Nature Reviews Drug Discovery.
[23] Xinbing Sui,et al. JNK confers 5-fluorouracil resistance in p53-deficient and mutant p53-expressing colon cancer cells by inducing survival autophagy , 2014, Scientific Reports.
[24] Jing Ye,et al. miR-34a Modulates Angiotensin II-Induced Myocardial Hypertrophy by Direct Inhibition of ATG9A Expression and Autophagic Activity , 2014, PloS one.
[25] M. Volpe,et al. Mammalian target of rapamycin signaling in cardiac physiology and disease. , 2014, Circulation research.
[26] Z. Qian,et al. Dissecting the Roles of miR-302/367 Cluster in Cellular Reprogramming Using TALE-based Repressor and TALEN , 2013, Stem cell reports.
[27] M. Zile,et al. Ceramide synthase 5 mediates lipid-induced autophagy and hypertrophy in cardiomyocytes. , 2012, The Journal of clinical investigation.
[28] K. Chowdhury,et al. The miRNA-212/132 family regulates both cardiac hypertrophy and cardiomyocyte autophagy , 2012, Nature Communications.
[29] L. Leinwand,et al. Cellular mechanisms of cardiomyopathy , 2011, The Journal of cell biology.
[30] K. Krause,et al. The miR 302-367 cluster drastically affects self-renewal and infiltration properties of glioma-initiating cells through CXCR4 repression and consequent disruption of the SHH-GLI-NANOG network , 2011, Cell Death and Differentiation.
[31] D. Hailey,et al. Autophagy termination and lysosome reformation regulated by mTOR , 2010, Nature.
[32] R. Gottlieb,et al. Autophagy during cardiac stress: joys and frustrations of autophagy. , 2010, Annual review of physiology.
[33] E. Sontheimer,et al. Origins and Mechanisms of miRNAs and siRNAs , 2009, Cell.
[34] D. Bartel. MicroRNAs: Target Recognition and Regulatory Functions , 2009, Cell.
[35] Y. Pinto,et al. Conditional Dicer Gene Deletion in the Postnatal Myocardium Provokes Spontaneous Cardiac Remodeling , 2008, Circulation.
[36] Pier Paolo Pandolfi,et al. Tenets of PTEN Tumor Suppression , 2008, Cell.
[37] D. Mann. MicroRNAs and the failing heart. , 2007, The New England journal of medicine.
[38] C. Croce,et al. MicroRNA-133 controls cardiac hypertrophy , 2007, Nature Medicine.
[39] Yasushi Matsumura,et al. The role of autophagy in cardiomyocytes in the basal state and in response to hemodynamic stress , 2007, Nature Medicine.
[40] Xiaoxia Qi,et al. Control of Stress-Dependent Cardiac Growth and Gene Expression by a MicroRNA , 2007, Science.
[41] Y. Maejima,et al. Drp 1-Dependent Mitochondrial Autophagy Plays a Protective Role Against Pressure-Overload-Induced Mitochondrial Dysfunction and Heart Failure , 2016 .
[42] T. Lai,et al. miR-302 Attenuates Amyloid-β-Induced Neurotoxicity through Activation of Akt Signaling. , 2016, Journal of Alzheimer's disease : JAD.
[43] N. Cai,et al. The microRNA-302-367 cluster suppresses the proliferation of cervical carcinoma cells through the novel target AKT1. , 2013, RNA.
[44] T. Rana,et al. Illuminating the silence: understanding the structure and function of small RNAs , 2007, Nature Reviews Molecular Cell Biology.
[45] P. Anversa,et al. Cardiac regeneration. , 2006, Journal of the American College of Cardiology.