IN-SITU SENSOR-BASED DAMAGE DETECTION OF COMPOSITE MATERIALS FOR STRUCTURAL HEALTH MONITORING

Compounds having kappa opioid agonist activity, compositions containing them and method of using them as analgesics and anti-pruritic agents are provided. The compounds of formular I, II, III and IV have the structure: (I) (II)X5, X7, X9; R1, R2, R3, R4; and Y, Z and n are as described in the specification.

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