New susceptibility alleles associated with severe coronary artery stenosis in the Lebanese population

[1]  Ji-Guang Wang,et al.  Genome-Wide Association Studies of Hypertension and Several Other Cardiovascular Diseases , 2019, Pulse.

[2]  Xia Li,et al.  DiseaseEnhancer: a resource of human disease-associated enhancer catalog , 2017, Nucleic Acids Res..

[3]  R. Hajar.  Risk Factors for Coronary Artery Disease: Historical Perspectives , 2017, Heart views : the official journal of the Gulf Heart Association.

[4]  Deanne M. Taylor,et al.  Genome-Wide Association Studies and Meta-Analyses for Congenital Heart Defects , 2017, Circulation. Cardiovascular genetics.

[5]  Diana Malaeb,et al.  The Prevalence and Awareness of Cardiovascular Diseases Risk Factors among the Lebanese Population: A Prospective Study Comparing Urban to Rural Populations , 2017, Cardiology research and practice.

[6]  Xiao Liu,et al.  Vascular smooth muscle cell glycocalyx mediates shear stress-induced contractile responses via a Rho kinase (ROCK)-myosin light chain phosphatase (MLCP) pathway , 2017, Scientific Reports.

[7]  M. Taggart,et al.  Altered Expression of Human Smooth Muscle Myosin Phosphatase Targeting (MYPT) Isovariants with Pregnancy and Labor , 2016, PloS one.

[8]  M. T. Dorak.  Genetic Association Studies: Background, Conduct, Analysis, Interpretation , 2016 .

[9]  R. Durbin,et al.  Evaluation of GRCh38 and de novo haploid genome assemblies demonstrates the enduring quality of the reference assembly , 2016, bioRxiv.

[10]  M. Goumans,et al.  WT1 in Cardiac Development and Disease , 2016 .

[11]  P. Noy,et al.  TspanC8 Tetraspanins and A Disintegrin and Metalloprotease 10 (ADAM10) Interact via Their Extracellular Regions , 2015, The Journal of Biological Chemistry.

[12]  Mitchell J. Machiela,et al.  LDlink: a web-based application for exploring population-specific haplotype structure and linking correlated alleles of possible functional variants , 2015, Bioinform..

[13]  Gabor T. Marth,et al.  A global reference for human genetic variation , 2015, Nature.

[14]  J. Danesh,et al.  A comprehensive 1000 Genomes-based genome-wide association meta-analysis of coronary artery disease , 2016 .

[15]  Kouichi Ozaki,et al.  Molecular genetics of coronary artery disease , 2015, Journal of Human Genetics.

[16]  R. Rosenthal.  The 50% coronary stenosis. , 2015, The American journal of cardiology.

[17]  Xiangyin Kong,et al.  Uncovering the Rare Variants of DLC1 Isoform 1 and Their Functional Effects in a Chinese Sporadic Congenital Heart Disease Cohort , 2014, PloS one.

[18]  J. Nielsen,et al.  Analysis of the Human Tissue-specific Expression by Genome-wide Integration of Transcriptomics and Antibody-based Proteomics* , 2013, Molecular & Cellular Proteomics.

[19]  Pavlos Pavlidis,et al.  1000 Genomes Selection Browser 1.0: a genome browser dedicated to signatures of natural selection in modern humans , 2013, Nucleic Acids Res..

[20]  R. Korstanje,et al.  Proprotein convertases in high-density lipoprotein metabolism , 2013, Biomarker Research.

[21]  Jung-Chien Cheng,et al.  ROS-mediated downregulation of MYPT1 in smooth muscle cells: a potential mechanism for the aberrant contractility in atherosclerosis , 2013, Laboratory Investigation.

[22]  Mary Goldman,et al.  The UCSC Genome Browser database: extensions and updates 2013 , 2012, Nucleic Acids Res..

[23]  Jean-Baptiste Cazier,et al.  Genome-Wide Association Study in a Lebanese Cohort Confirms PHACTR1 as a Major Determinant of Coronary Artery Stenosis , 2012, PloS one.

[24]  Jean-Baptiste Cazier,et al.  Large Scale Association Analysis Identifies Three Susceptibility Loci for Coronary Artery Disease , 2011, PloS one.

[25]  Mary Goldman,et al.  The UCSC Genome Browser database: extensions and updates 2011 , 2011, Nucleic Acids Res..

[26]  Yoshihiro Fukumoto,et al.  Rho-kinase: important new therapeutic target in cardiovascular diseases. , 2011, American journal of physiology. Heart and circulatory physiology.

[27]  Samir Alam,et al.  Parental consanguinity and family history of coronary artery disease strongly predict early stenosis. , 2010, Atherosclerosis.

[28]  Tanya M. Teslovich,et al.  Biological, Clinical, and Population Relevance of 95 Loci for Blood Lipids , 2010, Nature.

[29]  P. Salameh,et al.  CONSANGUINITY IN LEBANON: PREVALENCE, DISTRIBUTION AND DETERMINANTS , 2009, Journal of Biosocial Science.

[30]  R. J. Herrera,et al.  Y-Chromosomal Diversity in Lebanon Is Structured by Recent Historical Events , 2008, American journal of human genetics.

[31]  Manuel A. R. Ferreira,et al.  PLINK: a tool set for whole-genome association and population-based linkage analyses. , 2007, American journal of human genetics.

[32]  C. Gieger,et al.  Genomewide association analysis of coronary artery disease. , 2007, The New England journal of medicine.

[33]  Simon C. Potter,et al.  Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls , 2007, Nature.

[34]  Jonathan C. Cohen,et al.  A Common Allele on Chromosome 9 Associated with Coronary Heart Disease , 2007, Science.

[35]  Christopher G Sobey,et al.  Targeting Rho and Rho-kinase in the treatment of cardiovascular disease. , 2006, Trends in pharmacological sciences.

[36]  Qing Wang.  Molecular genetics of coronary artery disease , 2005, Current opinion in cardiology.

[37]  A. Gotto,et al.  Primary prevention of acute coronary events with lovastatin in men and women with average cholesterol levels: results of AFCAPS/TexCAPS. Air Force/Texas Coronary Atherosclerosis Prevention Study. , 1998, JAMA.

[38]  P. Elliott,et al.  Cardiovascular Genetics and Genomics , 2018, Springer International Publishing.

[39]  R. Praagh.  Definition of Conotruncal Anomalies , 2016 .

[40]  R. Roberts.  Genetics of coronary artery disease: an update. , 2014, Methodist DeBakey cardiovascular journal.

[41]  R Core Team,et al.  R: A language and environment for statistical computing. , 2014 .

[42]  D. Holmes,et al.  Coronary artery disease , 2012 .

[43]  Vienna Lecture,et al.  ON THE EUROPEAN UNION , 2010 .

[44]  Hilde van der Togt,et al.  Publisher's Note , 2003, J. Netw. Comput. Appl..

[45]  F. Sebening,et al.  [Coronary artery disease]. , 1980, Verhandlungen der Deutschen Gesellschaft fur Herz- und Kreislaufforschung.