Ossification in choroidal melanoma.

non-perfusion in the choroid as demonstrated on ICG.4 The lack of early masking on IVF and the sustained hypofluorescence of the lesions on ICG (which is highly protein bound and therefore stays in the circulatory system4), suggest that the lesions may represent areas of relative choroidal ischaemia. Previous authors have postulated that focal depigmented chorioretinal areas in sarcoidosis may correspond to subpigment epithelial granulomata similar to Dalen-Fuch's nodules (typically found in sympathetic ophthalmia).5 It has been suggested that these lesions may compress the choroidal vasculature rather than invade it. However, ocular postmortem examination of patients with fundal sarcoidosis has revealed non-caseating granulomata consisting mainly of epithelioid cells within the choroid, lymphocytic vascular cuffing was closely associated with these lesions.6 This may indicate a possible mechanism for the apparent vascular insufficiency of the choroid in the angiographic findings in our patient.