Carotid body tumors: A report of three cases and current literature review

Carotid body tumors are rare, slow-growing, hypervascular neuroendocrine tumors. Although these tumors are benign neoplasm, they also have a tendency to malignant transformation. Complete surgical excision is the gold standard therapeutic modality for the treatment of carotid body tumors. Early surgical removal is recommended to prevent the development of larger and more advanced tumors, which are associated with higher morbidity and mortality. In this report, we presented three cases of carotid body tumor which were successfully treated with complete surgical excision, and reviewed the current literature. Furthermore, it was emphasized the necessity of early surgical management regardless of patient age and tumor size. Correspondence to: Dr. Ahmet Yuksel, Department of Cardiovascular Surgery, Bursa State Hospital, Tophane Street, 16041, Bursa, Turkey, Tel: +90-505-8460753; Fax: +90-224-2132993; E-mail: ahmetyuksel1982@mynet.com

[1]  L. Pacheco-Ojeda Carotid body tumors: Surgical experience in 215 cases. , 2017, Journal of cranio-maxillo-facial surgery : official publication of the European Association for Cranio-Maxillo-Facial Surgery.

[2]  S. Money,et al.  Current surgical management of carotid body tumors. , 2016, Journal of vascular surgery.

[3]  T. Kręcicki,et al.  Diagnostic and Therapeutic Difficulties in Carotid Body Paragangliomas, Based on Clinical Experience and a Review of the Literature. , 2016, Advances in clinical and experimental medicine : official organ Wroclaw Medical University.

[4]  A. Chowhan,et al.  A Case of Large Carotid Body Tumor: Surgical Challenge , 2016 .

[5]  T. Lairmore,et al.  Surgical Management of Carotid Body Tumors: A 15-Year Single Institution Experience Employing an Interdisciplinary Approach , 2016, Proceedings.

[6]  R. Serra,et al.  Surgical complications of carotid body tumors surgery: a review. , 2015, International angiology : a journal of the International Union of Angiology.

[7]  T. Padhya,et al.  The Effects of Preoperative Embolization on Carotid Body Paraganglioma Surgery , 2015, Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery.

[8]  F. Snider,et al.  Cervical paragangliomas: single centre experience with 44 cases , 2015, Acta otorhinolaryngologica Italica : organo ufficiale della Societa italiana di otorinolaringologia e chirurgia cervico-facciale.

[9]  W. Mendenhall,et al.  Radiotherapy for benign head and neck paragangliomas: A 45‐year experience , 2014, Cancer.

[10]  F. Toktaş,et al.  Protective surgical procedures for carotid body tumors: a case series. , 2014 .

[11]  S. Agarwal,et al.  Neurological complications in carotid body tumors: a 6-year single-center experience. , 2013, Journal of vascular surgery.

[12]  Y. Tong Role of duplex ultrasound in the diagnosis and assessment of carotid body tumour: A literature review. , 2012, Intractable & rare diseases research.

[13]  D. Zeitler,et al.  Preoperative Embolization in Carotid Body Tumor Surgery: Is it Required? , 2010, The Annals of otology, rhinology, and laryngology.

[14]  J. Hamming,et al.  Resection of Carotid Body Tumors: Results of an Evolving Surgical Technique , 2008, Annals of surgery.

[15]  J. Gluckman,et al.  A Multidisciplinary Approach to Carotid Paragangliomas , 2007, Vascular and endovascular surgery.

[16]  M. Sajid,et al.  A multicenter review of carotid body tumour management. , 2007, European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery.

[17]  S. Stringer,et al.  Malignant carotid body tumor , 2004, Head & neck.

[18]  D. Frank,et al.  Combined endovascular and surgical treatment of head and neck paragangliomas—A team approach , 2002, Head & neck.

[19]  A. V. D. van der Mey,et al.  Management of carotid body tumors. , 2001, Otolaryngologic clinics of North America.

[20]  S. Sheps,et al.  Carotid body tumor (chemodectoma). Clinicopathologic analysis of ninety cases. , 1971, American journal of surgery.

[21]  G. Gordon‐Taylor On carotid tumours , 1940 .

[22]  S. Tăban,et al.  An evaluation on multidisciplinary management of carotid body paragangliomas: a report of seven cases. , 2016, Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologie.

[23]  C. Suárez Nieto,et al.  [Head and neck paragangliomas: revision of 89 cases in 73 patients]. , 2007, Acta otorrinolaringologica espanola.

[24]  K. Luna-Ortiz,et al.  Does Shamblin’s classification predict postoperative morbidity in carotid body tumors? A proposal to modify Shamblin’s classification , 2006, European Archives of Oto-Rhino-Laryngology and Head & Neck.