Design and synthesis of amphiphilic xanthone-based, membrane-targeting antimicrobials with improved membrane selectivity.
暂无分享,去创建一个
Lei Zhou | Rajamani Lakshminarayanan | Ai Ling Tan | Chandra Verma | Jianguo Li | H. Chan | D. Tan | C. Verma | R. Beuerman | S. Qiu | R. Lakshminarayanan | T. T. Aung | Lei Zhou | Donald T H Tan | Roger W Beuerman | Hanxun Zou | Jun-Jie Koh | Shengxiang Qiu | Thet Tun Aung | Huifen Lin | Xiaoping Dai | Charles Tang | Fang Hui Lim | Hardy Sze On Chan | Padmanabhan Saraswathi | Derong Cao | Shouping Liu | Shouping Liu | D. Cao | Jianguo Li | Jun-Jie Koh | Hanxun Zou | A. Tan | Fanghui Lim | Huifen Lin | X. Dai | Charles Tang | P. Saraswathi | Padmanabhan Saraswathi
[1] Sunil K. Vooturi,et al. Synthetic membrane-targeted antibiotics. , 2010, Current medicinal chemistry.
[2] Effect of structural parameters of peptides on dimer formation and highly oxidized side products in the oxidation of thiols of linear analogues of human β‐defensin 3 by DMSO , 2009, Journal of peptide science : an official publication of the European Peptide Society.
[3] J. Rolain,et al. Synthesis of new 3,20-bispolyaminosteroid squalamine analogues and evaluation of their antimicrobial activities. , 2011, Journal of medicinal chemistry.
[4] S. Vooturi,et al. Design, synthesis, and structure-activity relationships of benzophenone-based tetraamides as novel antibacterial agents. , 2009, Journal of medicinal chemistry.
[5] H. Nikaido. Molecular Basis of Bacterial Outer Membrane Permeability Revisited , 2003, Microbiology and Molecular Biology Reviews.
[6] H. Gold,et al. Antimicrobial resistance to linezolid. , 2004, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.
[7] Michael A Fischbach,et al. New antibiotics from bacterial natural products , 2006, Nature Biotechnology.
[8] H. Kauffmann,et al. Acute and repeat-dose toxicity studies of the (6-maleimidocaproyl)hydrazone derivative of doxorubicin (DOXO-EMCH), an albumin-binding prodrug of the anticancer agent doxorubicin , 2007, Human & experimental toxicology.
[9] G. Tew,et al. Antimicrobial activity of an abiotic host defense peptide mimic. , 2006, Biochimica et biophysica acta.
[10] P. Savage. Multidrug-resistant bacteria: overcoming antibiotic permeability barriers of Gram-negative bacteria , 2001, Annals of medicine.
[11] K. Schofield,et al. Heteroaromatic Nitrogen Compounds: The Azoles , 1967 .
[12] S. Yenugu,et al. The Androgen-Regulated Epididymal Sperm-Binding Protein, Human β-Defensin 118 (DEFB118) (Formerly ESC42), Is an Antimicrobial β-Defensin , 2004 .
[13] C. Verma,et al. Progressive Structuring of a Branched Antimicrobial Peptide on the Path to the Inner Membrane Target* , 2012, The Journal of Biological Chemistry.
[14] R. S. Coleman,et al. Synthesis of Secondary Amines , 2007 .
[15] M. Robbins,et al. Investigation of the Potential for Mutational Resistance to XF-73, Retapamulin, Mupirocin, Fusidic Acid, Daptomycin, and Vancomycin in Methicillin-Resistant Staphylococcus aureus Isolates during a 55-Passage Study , 2010, Antimicrobial Agents and Chemotherapy.
[16] P. Savage,et al. Activities of cholic acid-derived antimicrobial agents against multidrug-resistant bacteria. , 2001, The Journal of antimicrobial chemotherapy.
[17] A. Pini,et al. Characterization of the branched antimicrobial peptide M6 by analyzing its mechanism of action and in vivo toxicity , 2007, Journal of peptide science : an official publication of the European Peptide Society.
[18] K. Brogden. Antimicrobial peptides: pore formers or metabolic inhibitors in bacteria? , 2005, Nature Reviews Microbiology.
[19] Ping Shen,et al. Epidemiology and characteristics of antimicrobial resistance in China. , 2011, Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy.
[20] Robert Gurny,et al. Application of in vivo confocal microscopy to the objective evaluation of ocular irritation induced by surfactants. , 2000, International journal of pharmaceutics.
[21] R. Hancock,et al. Interaction of the Cyclic Antimicrobial Cationic Peptide Bactenecin with the Outer and Cytoplasmic Membrane* , 1999, The Journal of Biological Chemistry.
[22] P. Savage,et al. Correlation of the antibacterial activities of cationic peptide antibiotics and cationic steroid antibiotics. , 2002, Journal of medicinal chemistry.
[23] T. Beveridge,et al. Daptomycin Exerts Bactericidal Activity without Lysis of Staphylococcus aureus , 2008, Antimicrobial Agents and Chemotherapy.
[24] M. Nakamura,et al. Effects of antimicrobials on corneal epithelial migration. , 1993, Current eye research.
[25] R. Beuerman,et al. The effect of collagen shields on epithelial wound healing in rabbits. , 1989, American journal of ophthalmology.
[26] W. DeGrado,et al. Orientation, dynamics, and lipid interaction of an antimicrobial arylamide investigated by 19F and 31P solid-state NMR spectroscopy. , 2010, Journal of the American Chemical Society.
[27] Y. Sakagami,et al. Antibacterial activity of xanthones from Garcinia mangostana (L.) and their structure–activity relationship studies , 2013, Natural product research.
[28] G. Tew,et al. Influence of lipid composition on membrane activity of antimicrobial phenylene ethynylene oligomers. , 2008, The journal of physical chemistry. B.
[29] M. Yamada,et al. Corneal ulcer associated with deposits of norfloxacin. , 1998, American journal of ophthalmology.
[30] S. Cosgrove,et al. The Impact of Methicillin Resistance in Staphylococcus aureus Bacteremia on Patient Outcomes: Mortality, Length of Stay, and Hospital Charges , 2005, Infection Control & Hospital Epidemiology.
[31] S. Levy,et al. Antibacterial resistance worldwide: causes, challenges and responses , 2004, Nature Medicine.
[32] C. Verma,et al. Linear Analogues of Human β‐Defensin 3: Concepts for Design of Antimicrobial Peptides with Reduced Cytotoxicity to Mammalian Cells , 2008, Chembiochem : a European journal of chemical biology.
[33] J. Reidy,et al. Effect of topical beta blockers on corneal epithelial wound healing in the rabbit. , 1994, British Journal of Ophthalmology.
[34] Y. Ishitsuka,et al. Amphiphilic poly(phenyleneethynylene)s can mimic antimicrobial peptide membrane disordering effect by membrane insertion. , 2006, Journal of the American Chemical Society.
[35] Y. Pouliquen,et al. Antibiotics and corneal epithelial wound healing. , 1983, Archives of ophthalmology.
[36] C. Coopersmith,et al. Epithelial cells , 1991 .
[37] J. Etter,et al. Biopharmaceutical test of ocular irritation in the mouse. , 1985, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.
[38] P. Savage,et al. Antimicrobial Activities of Ceragenins against Clinical Isolates of Resistant Staphylococcus aureus , 2007, Antimicrobial Agents and Chemotherapy.
[39] L. Gutmann,et al. In Vitro Bactericidal Activities of Linezolid in Combination with Vancomycin, Gentamicin, Ciprofloxacin, Fusidic Acid, and Rifampin against Staphylococcus aureus , 2003, Antimicrobial Agents and Chemotherapy.
[40] William J. Allen,et al. Practical Considerations for Building GROMOS-Compatible Small-Molecule Topologies , 2010, J. Chem. Inf. Model..
[41] A. Kinghorn,et al. Antioxidant xanthones from the pericarp of Garcinia mangostana (Mangosteen). , 2006, Journal of agricultural and food chemistry.
[42] H. Taylor,et al. Increased incidence of corneal perforation after topical fluoroquinolone treatment for microbial keratitis. , 2001, American journal of ophthalmology.
[43] M. Vaara,et al. Agents that increase the permeability of the outer membrane. , 1992, Microbiological reviews.
[44] Ramesh Rathinakumar,et al. Broad-spectrum antimicrobial peptides by rational combinatorial design and high-throughput screening: the importance of interfacial activity. , 2009, Journal of the American Chemical Society.
[45] V. Adhami,et al. α-Mangostin, a xanthone from mangosteen fruit, promotes cell cycle arrest in prostate cancer and decreases xenograft tumor growth. , 2012, Carcinogenesis.
[46] P. Barie,et al. Increased mortality associated with methicillin-resistant Staphylococcus aureus (MRSA) infection in the intensive care unit: results from the EPIC II study. , 2011, International journal of antimicrobial agents.
[47] F. Tenover,et al. Methicillin-resistant Staphylococcus aureus clinical strain with reduced vancomycin susceptibility. , 1997, The Journal of antimicrobial chemotherapy.
[48] W. Bocian,et al. Genistein binding mode to doubly nicked dumbbell DNA. Dynamic and diffusion ordered NMR study. , 2011, Journal of medicinal chemistry.
[49] I. Vattulainen,et al. Role of phosphatidylglycerols in the stability of bacterial membranes. , 2008, Biochimie.
[50] A. Resch,et al. The cost of resistance: incremental cost of methicillin-resistant Staphylococcus aureus (MRSA) in German hospitals , 2009, The European Journal of Health Economics.
[51] S. Gad,et al. Acute toxicology testing , 1997 .
[52] D. Tan,et al. Rapid bactericidal action of alpha-mangostin against MRSA as an outcome of membrane targeting. , 2013, Biochimica et biophysica acta.
[53] S. Klyce,et al. Epithelial wound closure in the rabbit cornea. A biphasic process. , 1986, Investigative ophthalmology & visual science.
[54] I. Chopra,et al. Targeting bacterial membrane function: an underexploited mechanism for treating persistent infections , 2010, Nature Reviews Microbiology.
[55] Stefan Weigand,et al. Antibacterial natural products in medicinal chemistry--exodus or revival? , 2006, Angewandte Chemie.
[56] D. Weibel,et al. DCAP: A Broad‐spectrum Antibiotic that Targets the Cytoplasmic Membrane of Bacteria , 2012, Journal of the American Chemical Society.
[57] R. Nordquist,et al. Ciprofloxacin microprecipitates and macroprecipitates in the human corneal epithelium. , 2001, Journal of cataract and refractive surgery.
[58] R. Gennaro,et al. Cathelicidin peptides as candidates for a novel class of antimicrobials. , 2002, Current pharmaceutical design.
[59] Y. Shai,et al. Mode of action of membrane active antimicrobial peptides. , 2002, Biopolymers.
[60] William C Wimley,et al. Describing the mechanism of antimicrobial peptide action with the interfacial activity model. , 2010, ACS chemical biology.
[61] T. Tan,et al. Six cases of daptomycin-non-susceptible Staphylococcus aureus bacteraemia in Singapore. , 2010, Journal of medical microbiology.
[62] R. Beuerman,et al. Human recombinant epidermal growth factor in experimental corneal wound healing. , 1991, Investigative ophthalmology & visual science.
[63] S. Yenugu,et al. The androgen-regulated epididymal sperm-binding protein, human beta-defensin 118 (DEFB118) (formerly ESC42), is an antimicrobial beta-defensin. , 2004, Endocrinology.
[64] M. Poot,et al. Bacterial viability and antibiotic susceptibility testing with SYTOX green nucleic acid stain , 1997, Applied and environmental microbiology.
[65] Pramod C. Nair,et al. An Automated Force Field Topology Builder (ATB) and Repository: Version 1.0. , 2011, Journal of chemical theory and computation.
[66] L. Guo,et al. The structural parameters for antimicrobial activity, human epithelial cell cytotoxicity and killing mechanism of synthetic monomer and dimer analogues derived from hBD3 C-terminal region , 2010, Amino Acids.
[67] D. Albert,et al. In vitro toxicity of gentamicin to corneal epithelial cells. , 1990, Cornea.
[68] H. Vogel,et al. Diversity of antimicrobial peptides and their mechanisms of action. , 1999, Biochimica et biophysica acta.
[69] M. Maia,et al. Retinal and Ocular Toxicity in Ocular Application of Drugs and Chemicals – Part II: Retinal Toxicity of Current and New Drugs , 2010, Ophthalmic Research.
[70] A. Hidrón,et al. Antimicrobial-Resistant Pathogens Associated With Healthcare-Associated Infections: Annual Summary of Data Reported to the National Healthcare Safety Network at the Centers for Disease Control and Prevention, 2006–2007 , 2008, Infection Control & Hospital Epidemiology.
[71] H. Hall,et al. Correlation of the Base Strengths of Amines1 , 1957 .
[72] R. Hancock. Host defence (cationic) peptides: what is their future clinical potential? , 1999, Drugs.
[73] B. Levin,et al. Fitness Costs of Fluoroquinolone Resistance in Streptococcus pneumoniae , 2006, Antimicrobial Agents and Chemotherapy.
[74] M. Havelková,et al. Antimicrobial activity of small beta-peptidomimetics based on the pharmacophore model of short cationic antimicrobial peptides. , 2010, Journal of medicinal chemistry.
[75] M. Zasloff. Antimicrobial peptides of multicellular organisms , 2002, Nature.
[76] B. Brandsdal,et al. A synthetic antimicrobial peptidomimetic (LTX 109): stereochemical impact on membrane disruption. , 2011, Journal of medicinal chemistry.