The association between hypertension and glucose tolerance among adults with prediabetes in Hail City, Saudi Arabia.

OBJECTIVE As a worldwide epidemic, the frequency of prediabetes is rapidly increasing. As a result, the present study investigated pre-diabetes synergistic factors in the Saudi population. PATIENTS AND METHODS This descriptive study used samples from 31 Hail-area primary health clinics (PHCs). Participants were chosen at random from December 2021 to June 2022. RESULTS There were 164 participants in this study, of which 86 males (52.4%) and 78 females (47.6%). The GTT revealed that none of the study participants had diabetes, but an A1C test revealed that all of them had A1C levels above 6.5%. Approximately 16/86 (18.6%) of the 86 men were overweight, whereas 53/86 (61.6%) were obese. CONCLUSIONS Saudi Arabia's prediabetes rate has increased due to obesity/overweight, family history of diabetes, heart rate variability, and poor sleep quality. HbA1c screening should replace GTT to prevent progression to T2DM.

[1]  Yuli Zhang,et al.  Progression from prediabetes to type 2 diabetes mellitus induced by overnutrition , 2022, Hormones.

[2]  I. J. Goldberg,et al.  Management of Dyslipidemia and Atherosclerotic Cardiovascular Risk in Prediabetes. , 2022, Diabetes research and clinical practice.

[3]  Rasha A Almubark,et al.  Gender Differences in the Attitudes and Management of People with Obesity in Saudi Arabia: Data from the ACTION-IO Study , 2022, Risk management and healthcare policy.

[4]  K. Ha,et al.  Association of prediabetes with death and diabetic complications in older adults: the pros and cons of active screening for prediabetes. , 2022, Age and ageing.

[5]  Karla I. Galaviz,et al.  Interventions for Reversing Prediabetes: A Systematic Review and Meta-Analysis. , 2022, American journal of preventive medicine.

[6]  Shuohua Chen,et al.  Prediabetes and risk of stroke and its subtypes by hypertension status , 2022, Diabetes/metabolism research and reviews.

[7]  K. Khunti,et al.  Behavioural interventions to promote physical activity in a multiethnic population at high risk of diabetes: PROPELS three-arm RCT. , 2021, Health technology assessment.

[8]  W. Rathmann,et al.  Prediabetes and risk of mortality, diabetes-related complications and comorbidities: umbrella review of meta-analyses of prospective studies , 2021, Diabetologia.

[9]  H. Al-Hazzaa,et al.  Obesity, Lifestyle Behaviors, and Dietary Habits of Saudi Adolescents Living in Riyadh (ATLS-2 Project): Revisited after a Ten-Year Period , 2021, Life.

[10]  C. Holzapfel,et al.  Obesity, Nutrition and Heart Rate Variability , 2021, International journal of molecular sciences.

[11]  A. R. Aladro-Gonzalvo,et al.  Impact of Work and Recreational Physical Activity on Prediabetes Condition among U.S. Adults: NHANES 2015–2016 , 2021, International journal of environmental research and public health.

[12]  K. Lo,et al.  Prediabetes and risk for all-cause and cardiovascular mortality based on hypertension status , 2020, Annals of translational medicine.

[13]  E. Halperin,et al.  The causal effect of obesity on prediabetes and insulin resistance reveals the important role of adipose tissue in insulin resistance , 2020, PLoS genetics.

[14]  H. Crijns,et al.  Both Prediabetes and Type 2 Diabetes Are Associated With Lower Heart Rate Variability: The Maastricht Study , 2020, Diabetes Care.

[15]  Li Li,et al.  Associations between poor sleep and glucose intolerance in prediabetes , 2019, Psychoneuroendocrinology.

[16]  M. Batais,et al.  Prevalence of Prediabetes, Diabetes, and Its Associated Risk Factors among Males in Saudi Arabia: A Population-Based Survey , 2018, Journal of diabetes research.

[17]  F. Kronenberg,et al.  Family history of diabetes is associated with higher risk for prediabetes: a multicentre analysis from the German Center for Diabetes Research , 2013, Diabetologia.

[18]  堀内 光.  Prediabetes , 1964, Advances in Experimental Medicine and Biology.